CAS 5591-45-7

Tiotixeno

Descripción:

Tiotixeno es un medicamento antipsicótico utilizado principalmente en el tratamiento de la esquizofrenia y otros trastornos psicóticos. Pertenece a la clase de fármacos llamados tioxantenos y actúa como un antagonista de los receptores de dopamina, dirigiéndose particularmente a los receptores D2 en el cerebro. Esta acción ayuda a aliviar síntomas como alucinaciones y delirios. Tiotixeno se caracteriza por su estructura química, que incluye un núcleo de tioxanteno, contribuyendo a sus propiedades farmacológicas. La sustancia se administra típicamente en forma oral y es conocida por sus posibles efectos secundarios, que pueden incluir sedación, aumento de peso y síntomas extrapiramidales. Es importante monitorear a los pacientes por estos efectos durante el tratamiento. Además, Tiotixeno tiene una vida media relativamente larga, lo que permite una dosificación una o dos veces al día. Al igual que con todos los medicamentos antipsicóticos, es esencial considerar cuidadosamente el perfil de riesgo-beneficio, y debe ser prescrito bajo la guía de un profesional de salud calificado.

Fórmula: C₂₃H₂₉N₃O₂S₂

InChI: InChI=1/C23H29N3O2S2/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26/h4-5,7-11,17H,6,12-16H2,1-3H3/b19-8+

Clave InChI: InChIKey=GFBKORZTTCHDGY-UHFFFAOYSA-N

SMILES: C(CCN1CCN(C)CC1)=C2C=3C(SC=4C2=CC=CC4)=CC=C(S(N(C)C)(=O)=O)C3

Sinónimos:

• 2-(Dimethylsulfamoyl)-[9-(4-methyl-1-piperazinyl)propylidene]thioxanthene
• Cp 12252-1
• N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-9H-thioxanthene-2-sulfonamide
• N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]thioxanthene-2-sulfonamide
• N,N-Dimethyl-9-[3-(4-methylpiperazin-1-yl)propyliden]-9H-thioxanthen-2-sulfonamid
• N,N-dimethyl-9-[3-(4-methylpiperazin-1-yl)propylidene]-9H-thioxanthene-2-sulphonamide
• N,N-dimethyl-9-[3-(4-methylpiperazine-1-yl)propylidene]-9H-thioxanthene-2-sulfonamide
• N,N-dimetil-9-[3-(4-metilpiperazin-1-il)propiliden]-9H-tioxanteno-2-sulfonamida
• Navan
• Navane
• Navaron
• Nsc 108165
• Orbinamon
• P 4657B
• Thiothixene
• Thioxanthene-2-sulfonamide, N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-
• Thixit
• Tiotixene
• cis-Thiothixene
• 9H-Thioxanthene-2-sulfonamide, N,N-dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-
• N,N-dimethyl-9-[3-(4-methylpiperazin-1-yl)propylidene]thioxanthene-2-sulfonamide
• (9E)-N,N-dimethyl-9-[3-(4-methylpiperazin-1-yl)propylidene]-9H-thioxanthene-2-sulfonamide
• N,N-dimethyl-9-[3-(4-methylpiperazin-1-yl)propylidene]-9H-thioxanthene-2-sulfonamide
• n,n-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)thiaxanthene-2-sulfona
• N,N-Dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)thiaxanthene-2-sulfonamide
• 9H-Thioxanthene-2-sulfonamide, N,N-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)-, (Z)-
• 9h-thioxanthene-2-sulfonamide,n,n-dimethyl-9-(3-(4-methyl-1-piperazinyl)propyl
• n,n-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)thioxanthene-2-sulfona
• TIOTIXENE/THIOTHIXENE
• THIOTHIXENE,USP
• THIOTHIXENE MEETS USP TESTING SPECIFICA
• CP-12,252-1 base
• (Z)-N,N-dimethyl-9-(3-(4-methylpiperazin-1-yl)
• Thiothixine
• n,n-dimethyl-9-(3-(4-methyl-1-piperazinyl)propylidene)thioxanthene-2-sulfonami
• Thiothixene (Navane)
• (9Z)-N,N-Dimethyl-9-[3-(4-methyl-1-piperazinyl)propylidene]-9H-thioxanthene-2-sulfonamide
• cp12252-1

Thiothixene

CAS: 5591-45-7

Thiothixene has a wide range of applications in life science related research.

Fórmula: C₂₃H₂₉N₃O₂S₂

Forma y color: Solid

Peso molecular: 443.62

Ref: TM-T38200

Thiothixene-13C-d3

CAS: 5591-45-7

Fórmula: C₂₂₁₃CH₂₆D₃N₃O₂S₂

Peso molecular: 447.63

Ref: 4Z-T-228002

(Z)-Thiothixene-d8

Producto controlado

CAS: 5591-45-7

Fórmula: C₂₃H₂₁D₈N₃O₂S₂

Forma y color: Neat

Peso molecular: 451.67

Ref: TR-T375283

Thiothixene-d8

Producto controlado

CAS: 5591-45-7

Thiothixene is a drug used to treat schizophrenia that belongs to the class of antipsychotics. It is a serotonin reuptake inhibitor and has been shown to be effective in treating chronic schizophrenia. Thiothixene also has anti-nervous system activities, which are due to its ability to inhibit the release of acetylcholine. This drug binds with high affinity to α7 nicotinic acetylcholine receptors and blocks the flow of chloride ions across the cell membrane, leading to an accumulation of negatively charged ions inside the cell. The drug also inhibits mineralization and has been shown to prevent structural heart disease in animals. Thiothixene may be harmful if taken with pyrite or salinity because it can cause oxidative damage in redox potential environments. The drug can also cause plasma mass spectrometry profiles that show changes in carboniferous content, which may be related to the development of nervous system diseases.

Fórmula: C₂₃H₂₁D₈N₃O₂S₂

Pureza: Min. 95%

Peso molecular: 451.67 g/mol

Ref: 3D-FAA59145