CAS 56354-06-4

11-Nor-9-carboxi-Δ9-tetrahidrocannabinol

Descripción:

11-Nor-9-carboxi-Δ9-tetrahidrocannabinol, comúnmente conocido como THC-COOH, es un metabolito del tetrahidrocannabinol (THC), el principal componente psicoactivo del cannabis. Este compuesto se caracteriza por su grupo funcional ácido carboxílico, que lo distingue de su compuesto padre, el THC. El THC-COOH es típicamente no psicoactivo y a menudo se utiliza como un biomarcador en pruebas de drogas para indicar el uso de cannabis, ya que puede ser detectado en la orina durante un período prolongado después del consumo. La sustancia es lipofílica, lo que le permite acumularse en tejidos grasos, lo que contribuye a su presencia prolongada en el cuerpo. Su estructura molecular incluye un marco bicíclico típico de los cannabinoides, y exhibe una alta afinidad por los receptores cannabinoides, aunque con una actividad reducida en comparación con el THC. El compuesto es de interés en farmacología y toxicología, particularmente en estudios relacionados con el metabolismo del cannabis y los efectos del cannabis en la salud humana. Comprender sus características es crucial para interpretar pruebas de drogas y evaluar las implicaciones del uso de cannabis.

Fórmula: C₂₁H₂₈O₄

InChI: InChI=1S/C21H28O4/c1-4-5-6-7-13-10-17(22)19-15-12-14(20(23)24)8-9-16(15)21(2,3)25-18(19)11-13/h10-12,15-16,22H,4-9H2,1-3H3,(H,23,24)/t15-,16-/m1/s1

Clave InChI: InChIKey=YOVRGSHRZRJTLZ-HZPDHXFCSA-N

SMILES: OC1=C2[C@]3([C@](C(C)(C)OC2=CC(CCCCC)=C1)(CCC(C(O)=O)=C3)[H])[H]

Sinónimos:

• (-)-11-Nor-9-carboxy-Δ⁹-THC
• (6aR,10aR)-1-hydroxy-6,6-dimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromene-9-carboxylic acid
• (6aR,10aR)-6a,7,8,10a-Tetrahydro-1-hydroxy-6,6-dimethyl-3-pentyl-6H-dibenzo[b,d]pyran-9-carboxylic acid
• (±)11-Nor-9-carboxy-D9-THC
• 11-Nor-9-carboxy-⁹Δ-tetrahydrocannabinol
• 11-Nor-9-carboxy-THC
• 11-Nor-9-carboxy-Δ⁹-tetrahydrocannabinol
• 11-Nor-Δ⁹-tetrahydrocannabinol-9-carboxylic acid
• 11-nor-D9-tetrahydrocannabinol-9-*carboxylic acid
• 6H-Dibenzo[b,d]pyran-9-carboxylic acid, 6a,7,8,10a-tetrahydro-1-hydroxy-6,6-dimethyl-3-pentyl-, (6aR,10aR)-
• 6H-Dibenzo[b,d]pyran-9-carboxylic acid, 6a,7,8,10a-tetrahydro-1-hydroxy-6,6-dimethyl-3-pentyl-, (6aR-trans)-
• 9-Carboxy-11-nor-Δ⁹-tetrahydrocannabinol
• Tetrahydrocannabinol-7-oic acid
• l-11-Nor-9-carboxy-Δ⁹-tetrahydrocannabinol
• Δ¹-Tetrahydrocannabinol-7-oic acid
• Δ⁹-Tetrahydrocannabinol-11-oic acid
• Δ1-Tetrahydrocannabinol-7-oic acid

(-)-11-Nor-9-carboxy-δ9-THC 0.1 mg/ml in Methanol

Producto controlado

CAS: 56354-06-4

Forma y color: Single Solution

Ref: 61-AMP1088.06-02

(-)-11-Nor-9-carboxy-δ9-THC 1.0 mg/ml in Methanol

Producto controlado

CAS: 56354-06-4

Forma y color: Single Solution

Ref: 61-AMP1088.06-01

(-)-11-Nor-δ-9-THC carboxylic acid, 1mg/ml in Methanol

CAS: 56354-06-4

Forma y color: Single Solution

Ref: LP-THC-316-1LM

(-)-11-Nor-δ-9-THC carboxylic acid, 0.1mg/ml in Methanol

CAS: 56354-06-4

Forma y color: Single Solution

Ref: LP-THC-316-0.1LM

(-)-11-Nor-δ-9-THC carboxylic acid

CAS: 56354-06-4

Forma y color: Neat

Ref: LP-THC-316-10

(-)-11-Nor-9-carboxy-delta9-THC solution

Producto controlado

CAS: 56354-06-4

11-Nor-9-carboxy-9-THC is a metabolite of Δ9-tetrahydrocannabinol that is produced by the action of glucuronide conjugate. It can be found in human serum, urine, and blood as well as wastewater treatment plants. 11-Nor-9-carboxy-9-THC can be used to detect cannabis use in humans. The concentration of 11-nor - 9 - carboxy - 9 - THC in urine is proportional to the amount of cannabis consumed and its metabolites are detectable for up to 8 days after last use. 11 - Nor - 9 - carboxy - 9 - THC can also be detected in saliva, but not as reliably as in urine or blood. 11 - Nor - 9 - carboxy - 9 - THC has been shown to have pharmacokinetic properties that are similar to those of Δ9 tetrahydrocannabinol and other cannabinoids. These properties include

Fórmula: C₂₁H₂₈O₄

Pureza: Min. 95%

Forma y color: Clear Liquid

Peso molecular: 344.45 g/mol

Ref: 3D-GCA35406