CAS 566-28-9

7-Cetocolesterol

Descripción:

7-Cetocolesterol es un derivado oxidado del colesterol, caracterizado por la presencia de un grupo cetona en la posición C7 del núcleo esteroide. Su fórmula molecular es C27H46O y tiene un peso molecular de aproximadamente 402.65 g/mol. Este compuesto es un esteroide y se sabe que juega un papel en varios procesos biológicos, incluyendo la señalización celular y la fluidez de la membrana. 7-Cetocolesterol se estudia a menudo en el contexto de sus posibles implicaciones en la salud y la enfermedad, particularmente en relación con la aterosclerosis y los trastornos neurodegenerativos, ya que puede influir en el metabolismo del colesterol y la función celular. También se reconoce por su capacidad para inducir estrés oxidativo e inflamación en las células. En términos de propiedades físicas, 7-Cetocolesterol es típicamente un sólido blanco a blanco sucio, y es soluble en disolventes orgánicos pero tiene una solubilidad limitada en agua. Su reactividad e interacciones con otras biomoléculas lo convierten en un compuesto significativo tanto en bioquímica como en farmacología.

Fórmula: C₂₇H₄₄O₂

InChI: InChI=1/C27H44O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18,20-23,25,28H,6-15H2,1-5H3/t18?,20-,21+,22?,23?,25?,26-,27+/m0/s1

Clave InChI: InChIKey=YIKKMWSQVKJCOP-ABXCMAEBSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3=O)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@H](CCCC(C)C)C)[H])[H]

Sinónimos:

• (3Beta)-3-Hydroxycholest-5-En-7-One
• (3S,10R,13R,17R)-17-(1,5-dimethylhexyl)-3-hydroxy-10,13-dimethyl-1,2,3,4,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-7-one
• (3β)-3-Hydroxycholest-5-en-7-one
• (5Beta,7Alpha)-7-Hydroxy-3-Oxocholan-24-Oic Acid
• 3-Beta-Hydroxycholest-5-En-7-One
• 3β-Hydroxy-cholest-5-ene-7-one
• 3β-Hydroxycholest-5-en-7-one
• 5-cholesten-3B-ol-7-one
• 7-Ketocholesterol
• 7-Oxocholesterol
• Cholest-5-en-3β-ol-7-one
• Cholest-5-en-7-one, 3-hydroxy-, (3β)-
• Cholest-5-en-7-one, 3β-hydroxy-
• Sc 4722
• Δ5-Cholesten-3β-ol-7-one
• Δ⁵-Cholesten-3β-ol-7-one
• 5-CHOLESTEN-3BETA-OL-7-ONE
• 7-KetoC
• 5A-CHOLESTAN-3B-OL-7-ONE
• Ketocholesterol
• (3-beta)-cholest-5-en-7-on
• 7-Keto Cholesterol (~98%)
• 3BETA-HYDROXY-5-CHOLESTEN-7-ONE
• 3β-Hydroxy-5-cholesten-7-one, 7-Ketocholesterol
• 3-beta-hydroxy-cholest-5-en-7-on
• (3)-3-Hydroxycholest-5-en-7-one
• 3-hydroxy-5-cholestene-7-one
• 7-Ketocholesterolk
• Cholest-5-en-3-ol-7-one
• 7-Ketocholesterol (Solution)
• sc4722
• Cholesterol 7-Keto
• (3S,8S,9S,10R,13R,14S,17R)-17-[(1R)-1,5-dimethylhexyl]-3-hydroxy-10,13-dimethyl-1,2,3,4,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-7-one
• 7-oxo-cholestero
• Cholest-5-en-7-one, 3-hydroxy-, (3.beta.)-
• 3-Hydroxycholest-5-en-7-one
• 3β-hydroxy-5-cholesten-7-one
• (3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,3,4,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-7-one
• 3-HYDROXY-5-CHOLESTENE-7-ONE;7-KETOCHOLESTEROL
• 3-hydroxy-10,13-dimethyl-17-(6-methylheptan-2-yl)-1,2,3,4,8,9,11,12,14,15,1 6,17-dodecahydrocyclopenta[a]phenanthren-7-one

7-Ketocholesterol

CAS: 566-28-9

Fórmula: C₂₇H₄₄O₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 400.6371

Ref: IN-DA00E9IF

7-Keto-Cholesterol

CAS: 566-28-9

Fórmula: C₂₇H₄₄O₂

Peso molecular: 400.65

Ref: 4Z-C-5322

5-Cholesten-3Β-Ol-7-One

CAS: 566-28-9

5-Cholesten-3Β-Ol-7-One

Pureza: 98%

Peso molecular: 400.64g/mol

Ref: 54-OR1022895

7-Ketocholesterol

CAS: 566-28-9

7-Ketocholesterol

Pureza: ≥95%

Peso molecular: 400.65g/mol

Ref: 54-BUP06665

5-Cholesten-3β-ol-7-one

CAS: 566-28-9

Fórmula: C₂₇H₄₄O₂

Pureza: ≥ 98.0%

Forma y color: White to off-white powder

Peso molecular: 400.64

Ref: 7W-GL2633

7-Ketocholesterol

CAS: 566-28-9

Fórmula: C₂₇H₄₄O₂

Pureza: 95%~99%

Peso molecular: 400.647

Ref: BP-BP4652

7-Ketocholesterol

CAS: 566-28-9

7-Ketocholesterol is a metabolite of Cholesterol

Fórmula: C₂₇H₄₄O₂

Pureza: 97.59% - 98.84%

Forma y color: Solid

Peso molecular: 400.65

Ref: TM-TN6715

7-Keto Cholesterol

Producto controlado

CAS: 566-28-9

Applications 7-Keto Cholesterol is a metabolite of Cholesterol.
References Wang, J., et al.: Biochemistry, 43, 1010 (2004), Lemaire-Ewing, S., et al.: Cell Biol. Toxicol., 21, 97 (2005), Fuda, H., et al.: J. Lipid Res., 48, 1343 ( 2007), Sasaki, H., et al.: Metabolism, 56, 357 (2007),

Fórmula: C₂₇H₄₄O₂

Pureza: ~98%

Forma y color: Neat

Peso molecular: 400.64

Ref: TR-K185050

7-Ketocholesterol

Producto controlado

CAS: 566-28-9

7-Ketocholesterol is a reactive molecule that can induce inflammation and has been shown to be associated with eye disorders. 7-Ketocholesterol is an intermediate in the biosynthesis of cholesterol and is converted to 7-keto-cholesterol by the enzyme HMG-CoA reductase. This compound has also been shown to be a potent inducer of autophagy, which is a process that degrades intracellular components. 7-Ketocholesterol binds to cell nuclei and alters their shape, which may lead to cancerous cell growth. For example, this molecule induces apoptosis in cultured human retinal pigment epithelial cells. The mechanism of action for 7-ketocholesterol involves mitochondrial membrane potential, ATP binding cassette transporters, and DNA polymerase chain reaction (PCR).

Fórmula: C₂₇H₄₄O₂

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 400.64 g/mol

Ref: 3D-FK24766

7-Ketocholesterol

CAS: 566-28-9

Fórmula: C₂₇H₄₄O₂

Peso molecular: 400.6

Ref: ST-EA-CP-C71028