CAS 57710-57-3

ácido (2′S,5aS,6R,9aS)-1,5a,6,7,8,9a-hexahidro-6-(1-metiletil)-1-oxospiro[2-benzoxepina-9(3H),2′-oxirano]-4-carboxílico

Fórmula: C₁₅H₂₀O₅

InChI: InChI=1S/C15H20O5/c1-8(2)10-3-4-15(7-20-15)12-11(10)5-9(13(16)17)6-19-14(12)18/h5,8,10-12H,3-4,6-7H2,1-2H3,(H,16,17)/t10-,11-,12-,15-/m1/s1

Clave InChI: InChIKey=JESMSCGUTIEROV-RTWAVKEYSA-N

SMILES: O=C1[C@@]2([C@]3(CO3)CC[C@H](C(C)C)[C@]2(C=C(C(O)=O)CO1)[H])[H]

Sinónimos:

• (2′S,5aS,6R,9aS)-1,5a,6,7,8,9a-Hexahydro-6-(1-methylethyl)-1-oxospiro[2-benzoxepin-9(3H),2′-oxirane]-4-carboxylic acid
• Avocettin
• Heptelidic acid
• Spiro[2-benzoxepin-9(3H),2′-oxirane]-4-carboxylic acid, 1,5a,6,7,8,9a-hexahydro-6-(1-methylethyl)-1-oxo-, [5aS-(5aα,6α,9β,9aβ)]-
• Spiro[2-benzoxepin-9(3H),2′-oxirane]-4-carboxylic acid, 1,5a,6,7,8,9a-hexahydro-6-(1-methylethyl)-1-oxo-, (2′S,5aS,6R,9aS)-

Heptelidic acid

CAS: 57710-57-3

Fórmula: C₁₅H₂₀O₅

Pureza: 97%

Peso molecular: 280.3163

Ref: IN-DA00EWSJ

Heptelidic acid

CAS: 57710-57-3

Heptelidic acid

Pureza: ≥95%

Peso molecular: 280.32g/mol

Ref: 54-BUP21665

Heptelidic acid

CAS: 57710-57-3

Heptelidic acid (Koningic acid) is a selective GAPDH inhibitor that suppresses etoposide-induced apoptosis in HL-60 cells.

Fórmula: C₁₅H₂₀O₅

Forma y color: Solid

Peso molecular: 280.32

Ref: TM-T41305

Heptelidic acid

CAS: 57710-57-3

Fórmula: C₁₅H₂₀O₅

Pureza: ≥ 97.0%

Forma y color: White to off-white powder or solid

Peso molecular: 280.3

Ref: 7W-GL6923

Heptelidic acid

CAS: 57710-57-3

Heptelidic acid is a natural compound derived from the bark of the tree, "Heptelia verna". It is a type of sesquiterpene lactone that has been found to have anti-cancer properties. Heptelidic acid induces caspase-independent cell death by inhibiting mitochondrial membrane potential and controlling the expression of genes that are involved in energy metabolism. This compound also inhibits autophagy, which may be due to its ability to inhibit the transcriptional regulation of genes involved in this process.

Fórmula: C₁₅H₂₀O₅

Pureza: Min. 95%

Peso molecular: 280.32 g/mol

Ref: 3D-HCA71057