CAS 58-46-8

(±)-Tetrabenazina

Descripción:

(±)-Tetrabenazina es un compuesto químico que se utiliza principalmente como medicamento para el tratamiento de trastornos del movimiento, particularmente en condiciones como la enfermedad de Huntington y la discinesia tardía. Se clasifica como un agente que depleta monoaminas, dirigido específicamente a la depleción de neurotransmisores como la dopamina. El compuesto tiene una estructura compleja que presenta un núcleo de tetrabenazina, que contribuye a su actividad farmacológica. Es conocido por su capacidad para reducir los movimientos involuntarios al modular la actividad dopaminérgica en el cerebro. La sustancia se administra típicamente en su forma de sal hidrocloruro y se caracteriza por su relativamente baja solubilidad en agua, lo que influye en su biodisponibilidad. Los efectos secundarios pueden incluir sedación, depresión y trastornos gastrointestinales, lo que requiere un monitoreo cuidadoso durante el tratamiento. Debido a sus efectos sobre los niveles de neurotransmisores, (±)-Tetrabenazina se clasifica como una sustancia controlada en algunas jurisdicciones, reflejando su potencial de abuso y la necesidad de un uso regulado en entornos clínicos.

Fórmula: C₁₉H₂₇NO₃

InChI: InChI=1/C19H27NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16H,5-7,10-11H2,1-4H3/t14-,16-/s2

Clave InChI: InChIKey=MKJIEFSOBYUXJB-VTLFJGNJNA-N

SMILES: O(C)C=1C=C2[C@]3(N(C[C@H](CC(C)C)C(=O)C3)CCC2=CC1OC)[H]

Sinónimos:

• 2-Oxo-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo[a]quinolizine
• 2H-Benzo[A]Quinolizin-2-One, 1,3,4,6,7,11B-Hexahydro-9,10-Dimethoxy-3-(2-Methylpropyl)-, (3R,11Br)-Rel-
• 2H-Benzo[a]quinolizin-2-one, 1,3,4,6,7,11b-hexahydro-3-isobutyl-9,10-dimethoxy-
• 2H-Benzo[a]quinolizin-2-one, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-, cis-
• 2H-benzo[a]quinolizin-2-one, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-
• 3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one
• 9,10-Dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isochinolin-2-on
• 9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one
• Nsc 169886
• Nsc 172187
• Ro 1-9569
• Rubigen
• Tetrabenazin
• Tetrabenazina
• Xenazine
• cis-2-Oxo-3-isobutyl-9,10-dimethoxy-1,2,3,4,6,7-hexahydro-11bH-benzo[a]quinolizine

Tetrabenazine

CAS: 58-46-8

Fórmula: C₁₉H₂₇NO₃

Pureza: >99.0%(T)(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 317.43

Ref: 3B-T2839

Tetrabenazine ((3RS,11bRS)-3-Isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one)

CAS: 58-46-8

Drugs primarily affecting the central nervous system, not elsewhere specified or included

Fórmula: C₁₉H₂₇NO₃

Forma y color: White Crystalline Powder

Peso molecular: 317.19909

Ref: 45-1649801

TETRABENAZINE

CAS: 58-46-8

Fórmula: C₁₉H₂₇NO₃

Pureza: 98%

Forma y color: Solid

Peso molecular: 317.4226

Ref: IN-DA003UMF

Tetrabenazine

CAS: 58-46-8

Tetrabenazine (Ro 1-9569) is a drug formerly used as an antipsychotic and treatment of various movement disorders.

Fórmula: C₁₉H₂₇NO₃

Pureza: 98% - 99.91%

Forma y color: White To Off-White White To Off-White Solid

Peso molecular: 317.42

Ref: TM-T0719

Tetrabenazine-d7

CAS: 58-46-8

Fórmula: C₁₉H₂₀D₇NO₃

Forma y color: White To Off-White Solid

Peso molecular: 324.47

Ref: 4Z-T-782

Tetrabenazine

CAS: 58-46-8

Fórmula: C₁₉H₂₇NO₃

Forma y color: White To Off-White Solid

Peso molecular: 317.43

Ref: 4Z-T-781

Tetrabenazine

CAS: 58-46-8

Tetrabenazine

Pureza: 99%

Peso molecular: 317.42g/mol

Ref: 54-OR1028221

Tetrabenazine

CAS: 58-46-8

Tetrabenazine

Pureza: ≥98%

Peso molecular: 317.42g/mol

Ref: 54-BUP15812

Tetrabenazine

CAS: 58-46-8

Fórmula: C₁₉H₂₇NO₃

Peso molecular: 317.42

Ref: 7W-GK0293

Tetrabenazine

CAS: 58-46-8

Fórmula: C₁₉H₂₇NO₃

Forma y color: Neat

Peso molecular: 317.42

Ref: 86-MM1633.01

3-ISOBUTYL-9,10-DIMETHOXY-3,4,6,7-TETRAHYDRO-1H-PYRIDO[2,1-A]ISOQUINOLIN-2(11BH)-ONE

CAS: 58-46-8

Pureza: 97.0%

Forma y color: Solid

Peso molecular: 317.4289855957031

Ref: 10-F301460

Tetrabenazine - Bio-X ™

Producto controlado

CAS: 58-46-8

Tetrabenazine is a drug that has been used for the treatment of Parkinson's disease. It acts by inhibiting dopamine release and reducing the activity of nerve cells in the brain. Tetrabenazine Bio-X is used to treat dyskinesias, that are abnormal and involuntary muscle movements by inhibiting the monoamine transporter (VMAT2).
Tetrabenazine is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use."

Fórmula: C₁₉H₂₇NO₃

Pureza: Min. 99 Area-%

Forma y color: White Powder

Peso molecular: 317.42 g/mol

Ref: 3D-BT164463

Tetrabenazine

Producto controlado

CAS: 58-46-8

Applications Dopamine depleting agent. An antidyskinetic; antipsychotic.
References Schwartz, et al.: Biochem. Pharmacol., 15, 645 (1966), Janovic, J., et al.: Ann. Neurol., 11, 41 (1982), Janovic, J., et al.: Neurology, 38, 391 (1988),

Fórmula: C₁₉H₂₇NO₃

Forma y color: Neat

Peso molecular: 317.42

Ref: TR-T284000

Tetrabenazine

Producto controlado

CAS: 58-46-8

Tetrabenazine is a drug that has been used for the treatment of Parkinson's disease. It acts by inhibiting dopamine release and reducing the activity of nerve cells in the brain. Tetrabenazine Bio-X is used to treat dyskinesias, that are abnormal and involuntary muscle movements by inhibiting the monoamine transporter (VMAT2).

Fórmula: C₁₉H₂₇NO₃

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 317.42 g/mol

Ref: 3D-FT28060