CAS 581-05-5

hormona alfa-estimulante de melanocitos

Descripción:

La hormona estimulante de melanocitos alfa (α-MSH) es una hormona peptídica que desempeña un papel crucial en la regulación de varios procesos fisiológicos, incluida la pigmentación, el apetito y la homeostasis energética. Se deriva del precursor pro-opiomelanocortina (POMC) y consiste en una secuencia de 13 aminoácidos. La función principal de α-MSH es estimular la melanogénesis, la producción de melanina en los melanocitos, lo que afecta la pigmentación de la piel y el cabello. Además, se ha implicado a α-MSH en la modulación de las respuestas inflamatorias y la regulación del apetito, influyendo en el peso corporal y el metabolismo. La sustancia se caracteriza por su capacidad para unirse a los receptores de melanocortina, particularmente MC1R, que media sus efectos sobre la pigmentación. α-MSH también está involucrada en el sistema nervioso central, donde puede afectar el comportamiento y el equilibrio energético. Debido a sus diversos roles, α-MSH es de interés en la investigación relacionada con trastornos de la piel, obesidad y enfermedades metabólicas. Su número CAS, 581-05-5, se utiliza para la identificación en bases de datos químicas y contextos regulatorios.

Fórmula: C₇₇H₁₀₉N₂₁O₁₉S

InChI: InChI=1/C77H109N21O19S/c1-42(2)64(65(79)106)97-75(116)61-20-13-30-98(61)76(117)54(18-10-11-28-78)88-62(103)38-85-66(107)57(34-46-36-84-50-17-9-8-16-49(46)50)94-67(108)51(19-12-29-83-77(80)81)89-70(111)55(32-44-14-6-5-7-15-44)92-72(113)58(35-47-37-82-41-86-47)95-68(109)52(25-26-63(104)105)90-69(110)53(27-31-118-4)91-74(115)60(40-100)96-71(112)56(33-45-21-23-48(102)24-22-45)93-73(114)59(39-99)87-43(3)101/h5-9,14-17,21-24,36-37,41-42,51-61,64,84,99-100,102H,10-13,18-20,25-35,38-40,78H2,1-4H3,(H2,79,106)(H,82,86)(H,85,107)(H,87,101)(H,88,103)(H,89,111)(H,90,110)(H,91,115)(H,92,113)(H,93,114)(H,94,108)(H,95,109)(H,96,112)(H,97,116)(H,104,105)(H4,80,81,83)/t51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,64-/m0/s1

SMILES: CC(C)[C@@H](C(=N)O)N=C([C@@H]1CCCN1C(=O)[C@H](CCCCN)N=C(CN=C([C@H](Cc1c[nH]c2ccccc12)N=C([C@H](CCCNC(=N)N)N=C([C@H](Cc1ccccc1)N=C([C@H](Cc1cnc[nH]1)N=C([C@H](CCC(=O)O)N=C([C@H](CCSC)N=C([C@H](CO)N=C([C@H](Cc1ccc(cc1)O)N=C([C@H](CO)N=C(C)O)O)O)O)O)O)O)O)O)O)O)O

Sinónimos:

• .alpha.-MSH
• Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
• N-acetyl-L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valinamide
• melanotan,α-MSH,PT-141

α-Melanocyte Stimulating Hormone amide

CAS: 581-05-5

alpha-Melanocyte Stimulating Hormone amide; An endogenous melanocortin receptor agonist. Anti-inflammatory peptide; antagonizes proinflammatory mediators, including TNF-, IL-6 and NO and induces anti-inflammatory cytokine IL-10.

Fórmula: C₇₇H₁₀₉N₂₁O₁₉S

Peso molecular: 1664.88

Ref: 02-J64310

α-MSH

CAS: 581-05-5

α-Melanotropin, also known as α-melanocyte-stimulating hormone (α-MSH), is a 13-amino acid peptide originally characterized as a neuropeptide derived from the pituitary gland. α-MSH is synthesized from pro-opiomelanocortin (POMC) by the action of specific prohormone convertases and is involved in the regulation of important physiological functions including food intake, energy homeostasis, modulation of immune responses and photoprotection.

Fórmula: C₇₇H₁₀₉N₂₁O₁₉S

Pureza: 98.2%

Forma y color: White Lyophilisate

Peso molecular: 1664.91

Ref: 01-4008476

N-Acetyl-L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valinamide

CAS: 581-05-5

Fórmula: C₇₇H₁₀₉N₂₁O₁₉S

Pureza: 99%

Forma y color: Solid

Peso molecular: 1664.8837

Ref: IN-DA00E8UA

α-MSH

CAS: 581-05-5

α-MSH (MSH, amide) is amide stimulates melanocortin 1 receptor that results in the activation of adenylyl cyclase.

Fórmula: C₇₇H₁₀₉N₂₁O₁₉S

Pureza: 99.10% - 99.67%

Forma y color: White Powder

Peso molecular: 1664.89

Ref: TM-T7813

a-MSH, amide

CAS: 581-05-5

Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool

Fórmula: C₁₁₈H₁₇₄N₃₄O₃₅S

Peso molecular: 1,664.91 g/mol

Ref: 3D-PP50839

α-MSH (Human, Porcine, Bovine, Rat, Mouse)

CAS: 581-05-5

Alpha-MSH is a peptide that binds to the Melanocortin 1 receptor. Alpha-MSH is a peptide hormone and neurotransmitter that is involved in the regulation of numerous physiological processes, including appetite, sexual desire, immune response, and skin pigmentation. In addition to its role as a natural hormone, it has been studied as a potential drug for the treatment of obesity and other diseases. The product can also be used as an antibody probe for Western blotting or immunohistochemistry.  The product is produced synthetically.

Fórmula: C₇₇H₁₀₉N₂₁O₁₉S

Pureza: Min. 95%

Peso molecular: 1,664.9 g/mol

Ref: 3D-PMR-4057-V

α-MSH

CAS: 581-05-5

Custom research peptide; min purity 95%.

Fórmula: C₇₇H₁₀₉N₂₁O₁₉S

Pureza: Min. 95%

Peso molecular: 1,664.9 g/mol

Ref: 3D-PM17126