CAS 58288-50-9

Hidroxocobalamina hidrocloruro

Descripción:

Hidroxocobalamina hidrocloruro es una forma de vitamina B12, específicamente un compuesto de cobalamina, caracterizado por su color rojo debido a la presencia de cobalto. Es una vitamina soluble en agua que desempeña un papel crucial en varios procesos biológicos, incluida la síntesis de ADN, la formación de glóbulos rojos y la función neurológica. La hidroxocobalamina se utiliza a menudo en entornos clínicos como tratamiento para la deficiencia de vitamina B12 y como antídoto para el envenenamiento por cianuro debido a su capacidad para unirse a los iones de cianuro, formando un complejo no tóxico. El compuesto se administra típicamente por vías intramusculares o intravenosas, y su farmacocinética implica almacenamiento en el hígado, donde puede liberarse según sea necesario. Hidroxocobalamina hidrocloruro generalmente es bien tolerado, con efectos secundarios que son raros pero pueden incluir reacciones alérgicas o reacciones en el sitio de inyección. Su estabilidad y eficacia lo convierten en un agente terapéutico valioso tanto en la suplementación nutricional como en la medicina de emergencia.

Fórmula: C₆₂H₈₉CoN₁₃O₁₅P·xClH

InChI: InChI=1S/C62H90N13O14P.ClH.Co.H2O/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H;;1H2/q;;+3;/p-3

Clave InChI: InChIKey=KEHNCSYXYMMUCO-UHFFFAOYSA-K

SMILES: [OH-][Co+3]1234[N]=5C6(C)C7[N-]1C(C(C)(C7CC(N)=O)CCC(=O)NCC(C)OP(=O)([O-])OC8C(O)C(N9C=[N]2C=%10C9=CC(C)=C(C)C%10)OC8CO)=C(C)C%11=[N]3C(=CC%12=[N]4C(=C(C)C5C(CCC(N)=O)C6(CC(N)=O)C)C(CC(N)=O)(C)C%12CCC(N)=O)C(C)(C)C%11CCC(N)=O.Cl

Sinónimos:

• Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3′-ester with (5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole-κN³), hydrochloride
• Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3′-ester with (5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole-κN³), hydrochloride (1:?)
• Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono(inner salt), 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole, hydrochloride
• Hydroxocobalamin Chloride
• Hydroxocobalamine Hydrochloride
• Vitamin B12A Hydrochloride
• hydroxocobalamin HCl
• hydroxy-[(1R,2R,3R,4Z,7S,9Z,12S,13S,14Z,17S,18S,19R)-2,13,18-tris(2-amino-2-oxo-ethyl)-7,12,17-tris(3-amino-3-oxo-propyl)-3-[3-[[(2R)-2-[[(2R,3S,4R,5S)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl]oxy-oxido-phosphoryl]oxypropyl]amino]-3-oxo-propyl]-3,5,8,8,13,15,18,19-octamethyl-2,7,12,17-tetrahydro-1H-corrin-21-yl]cobalt(1+) hydrochloride
• Hydroxocobalamin hydrochloride
• Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3′-ester with (5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3), hydrochloride
• Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3′-ester with (5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3), hydrochloride (1:?)

HYDROXOCOBALAMIN CRS

CAS: 58288-50-9

HYDROXOCOBALAMIN CRS

Ref: 41-H1428000

Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3'-esterwith (5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole-kN3),hydrochloride

CAS: 58288-50-9

Fórmula: C₆₂H₉₀ClCoN₁₃O₁₅P

Pureza: 98%

Forma y color: Solid

Peso molecular: 1382.8161

Ref: IN-DA00E91P

Vitamin B12a hydrochloride

CAS: 58288-50-9

Vitamin B12a monohydrochloride (Hydroxocobalamin) is an essential water-soluble vitamin.a cyanide detoxifier and nutritional supplement, injection, inhalation.

Fórmula: C₆₂H₈₉CoN₁₃O₁₅P·xHCl

Forma y color: Solid

Ref: TM-T204095

Hydroxocobalamin hydrochloride

CAS: 58288-50-9

Fórmula: C₆₂H₈₉CoN₁₃O₁₅P·HCl

Pureza: 96.0 - 102.0 %

Forma y color: Off-white to dark red or brown crystalline powder

Peso molecular: 1382.82

Ref: 7W-GE2054

Hydroxocobalamin Xhydrochloride

CAS: 58288-50-9

Hydroxocobalamin Xhydrochloride

Pureza: 98%

Peso molecular: 1,382.82g/mol

Ref: 54-OR1013543

Vitamin B12a

CAS: 58288-50-9

Fórmula: C₆₂H₉₀ClCoN₁₃O₁₅P

Peso molecular: 1382.82

Ref: 7W-GL8242

Hydroxocobalamin HCl

CAS: 58288-50-9

Hydroxocobalamin HCl is a vitamin that is required for the formation of coenzyme B12. It is used to treat megaloblastic anemia, pernicious anemia, and other conditions in which vitamin B12 is deficient. Hydroxocobalamin HCl also has been shown to have physiological effects, including the inhibition of enzyme activities such as nitrite reductase and sephadex g-100. This drug binds to a number of enzymes, including group P2 enzymes (e.g., nitrate reductase) and thermolytic enzymes (e.g., hydroxylases). Hydroxocobalamin HCl has a redox potential that allows it to act as a hydrogen donor in reactions with electron acceptors such as nitrite ion or oxygen. The mechanism of action of hydroxocobalamin includes its ability to reduce intramolecular hydrogen molecules, which can be transferred to other molecules in the reaction system such as

Fórmula: C₆₂H₈₉CoN₁₃O₁₅P•(HCl)x

Pureza: Min. 90 Area-%

Forma y color: Powder

Peso molecular: 1,346.35 g/mol

Ref: 3D-FH45888

Hydroxocobalamin Hydrochloride (>85%)

CAS: 58288-50-9

Applications Hydroxocobalamin Hydrochloride acts as a spin trap for radical polymerization in water when reduced with ascorbic acid.
References Ng, Y., et al.: Macromol. Res., 20, 473-476 (2012)

Fórmula: C₆₂H₈₉CoN₁₃O₁₅P·ClH

Forma y color: Neat

Peso molecular: 1382.82

Ref: TR-H862823

Cyanocobalamin EP Impurity H Chloride (Hydroxocobalamin Chloride)

CAS: 58288-50-9

Fórmula: C₆₂H₈₉CoN₁₃O₁₅P·HCl

Peso molecular: 1382.82 36.46

Ref: 4Z-C-165020