CAS 58546-56-8

Schisantherin A

Descripción:

Schisantherin A es un compuesto natural clasificado como un lignano, derivado principalmente de la especie vegetal Schisandra chinensis, conocida por sus propiedades medicinales. Este compuesto exhibe una estructura molecular compleja caracterizada por múltiples anillos aromáticos y grupos hidroxilo, lo que contribuye a su actividad biológica. Schisantherin A es reconocido por sus propiedades antioxidantes, que ayudan a eliminar radicales libres y reducir el estrés oxidativo. Además, se ha estudiado por sus posibles efectos neuroprotectores, actividades antiinflamatorias y capacidad para modular diversas vías de señalización en las células. El perfil farmacológico del compuesto sugiere aplicaciones potenciales en la medicina tradicional, particularmente en la mejora de la función hepática y la promoción de la salud en general. Su solubilidad y estabilidad en varios disolventes lo hacen adecuado para investigaciones y desarrollos adicionales en los campos de la farmacología y la química de productos naturales. Al igual que con muchos compuestos naturales, los estudios en curso son esenciales para elucidar completamente sus mecanismos de acción y potencial terapéutico.

Fórmula: C₃₀H₃₂O₉

InChI: InChI=1S/C30H32O9/c1-16-12-18-13-21-25(38-15-37-21)26(35-5)22(18)23-19(14-20(33-3)24(34-4)27(23)36-6)28(30(16,2)32)39-29(31)17-10-8-7-9-11-17/h7-11,13-14,16,28,32H,12,15H2,1-6H3

Clave InChI: InChIKey=UFCGDBKFOKKVAC-UHFFFAOYSA-N

SMILES: O(C)C1=C2C=3C(=CC4=C(C3OC)OCO4)CC(C)C(C)(O)C(OC(=O)C5=CC=CC=C5)C2=CC(OC)=C1OC

Sinónimos:

• (5R,6S,7S)-6-hydroxy-1,2,3,13-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-5-yl benzoate
• (5S,6S,7S)-6-hydroxy-1,2,3,13-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-5-yl benzoate
• (5S-(5alpha,6beta,7beta))-5,6,7,8-Tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethylbenzo(3,4)cycloocta(1,2-f)(1,3)benzodioxole-5,6-diol 5-benzoate
• 6-Hydroxy-1,2,3,13-Tetramethoxy-6,7-Dimethyl-5,6,7,8-Tetrahydrobenzo[3',4']Cycloocta[1',2':4,5]Benzo[1,2-D][1,3]Dioxol-5-Yl Benzoate
• Benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxole-5,6-diol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, 5-benzoate, (5S-(5alpha,6beta,7beta))-
• Benzo[3,4]cycloocta[1,2-f][1,3]benzodioxole-5,6-diol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, 5-benzoate, (5S,6S,7S,13aS)-
• Benzo[3,4]cycloocta[1,2-f][1,3]benzodioxole-5,6-diol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, 5-benzoate, stereoisomer
• Gomisin C
• Schizantherin A
• Wuweizi ester A
• Schisantherin A

Schisantherin A

CAS: 58546-56-8

Fórmula: C₃₀H₃₂O₉

Pureza: 98%

Forma y color: Solid

Peso molecular: 536.5697

Ref: IN-DA00E96C

Schizantherin A

CAS: 58546-56-8

Fórmula: C₃₀H₃₂O₉

Peso molecular: 536.58

Ref: 7W-GY0185

Schisantherin A

CAS: 58546-56-8

Schisantherin A

Pureza: ≥98%

Peso molecular: 536.57g/mol

Ref: 54-BUP00173

Schisantherin A

CAS: 58546-56-8

Schisantherin A

Pureza: 98%

Peso molecular: 536.57g/mol

Ref: 54-OR1025610

Gomisin C

CAS: 58546-56-8

Fórmula: C₃₀H₃₂O₉

Pureza: >98.0%(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 536.58

Ref: 3B-G0538

Schizantherin A

CAS: 58546-56-8

Schisantherin A exhibits anti-tussive, sedative, anti-inflammatory, antioxidant, anti-osteoporotic, neuroprotective, cognition enhancing, and cardioprotective activities. Schisantherin A can significantly attenuate Aβ1-42-induced learning and memory impairment and noticeably improve the histopathological changes in the hippocampus. Schisantherin A exhibits neuroprotection against 1-methyl-4-phenylpyridinium ion (MPP(+)) through the regulation of two distinct pathways including increasing CREB-mediated Bcl-2 expression and activating PI3K/Akt survival signaling.

Fórmula: C₃₀H₃₂O₉

Pureza: 95%~99%

Peso molecular: 536.577

Ref: BP-BP1267

Schisantherin A

CAS: 58546-56-8

Schisantherin A, a lignan from Schisandra fruit, is used as an antitussive, tonic, and sedative.

Fórmula: C₃₀H₃₂O₉

Pureza: 98% - 99.989

Forma y color: Solid

Peso molecular: 536.57

Ref: TM-T2913

Schisantherin a

CAS: 58546-56-8

Carboxylic acid with additional oxygen functions

Fórmula: C₃₀H₃₂O₉

Pureza: ≥ 95.0 % (HPLC)

Forma y color: Powder

Peso molecular: 536.58

Ref: 5G-89316

Gomisin C

Producto controlado

CAS: 58546-56-8

Gomisin C is a natural compound that has been shown to have antioxidant and anti-inflammatory effects. It has been shown to inhibit the mitochondrial membrane potential, which leads to cytosolic Ca2+ accumulation. Gomisin C also inhibits 3T3-L1 preadipocyte differentiation. This compound also inhibits the polymerase chain reaction of DNA in cells, as well as the formation of crystalline cellulose and fructus. Gomisin C has been shown to be effective against neuronal death induced by ischemia–reperfusion injury and skin tumor formation induced by chemical carcinogens. It also inhibits drug transporter activity, voltage-dependent calcium channels, and enzyme activities.

Fórmula: C₃₀H₃₂O₉

Pureza: 80%

Forma y color: White Powder

Peso molecular: 536.57 g/mol

Ref: 3D-FG09971

Schisantherin A

Producto controlado

CAS: 58546-56-8

Applications Schisantherin A is a ligand from Schisandra chinensis. It is capable of suppressing interleukin-1β-induced inflammation in human chondrocytes by inhibiting NF-κB and MAPKs activation.
References ?Liao, S. et al.: Eur. J. Pharmacol 780, 65 (2016); Liu, H., et al.: J Funct Foods 19, 296 (2015)

Fórmula: C₃₀H₃₂O₉

Forma y color: Neat

Peso molecular: 536.57

Ref: TR-S199100