CAS 58909-56-1

Ácido (6R,7R)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahidro-2-metil-5,6-dioxo-1,2,4-triazin-3-il)tio]metil]-5-tia-1-azabiciclo[4.2.0]oct-2-eno-2-carboxílico

Descripción:

La sustancia química conocida como Ácido (6R,7R)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahidro-2-metil-5,6-dioxo-1,2,4-triazin-3-il)tio]metil]-5-tia-1-azabiciclo[4.2.0]oct-2-eno-2-carboxílico, con el número CAS 58909-56-1, es un compuesto orgánico complejo que pertenece a una clase de moléculas conocidas por sus posibles propiedades farmacológicas. Este compuesto presenta una estructura bicíclica, que contribuye a su reactividad química única y actividad biológica. La presencia de grupos funcionales amino y ácido carboxílico sugiere que puede exhibir características polares, lo que podría influir en su solubilidad e interacción con sistemas biológicos. Además, la incorporación de un tioéter y un moiety de triazina indica que puede tener mecanismos de acción específicos, posiblemente relacionados con actividades antimicrobianas o antivirales. En general, la intrincada estructura y los grupos funcionales de este compuesto lo convierten en un tema de interés en la química medicinal y el desarrollo de fármacos, lo que justifica una mayor investigación sobre su potencial terapéutico y mecanismos de acción.

Fórmula: C₁₂H₁₃N₅O₅S₂

InChI: InChI=1/C12H13N5O5S2/c1-16-12(14-7(18)8(19)15-16)24-3-4-2-23-10-5(13)9(20)17(10)6(4)11(21)22/h5,10H,2-3,13H2,1H3,(H,15,19)(H,21,22)/t5-,10-/m0/s1

Clave InChI: InChIKey=YTUNICCSPPTMJY-GPXNAGAYSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](N)C2=O)(SCC1CSC=3N(C)NC(=O)C(=O)N3)[H]

Sinónimos:

• (6R,7R)-7-Amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6S,7S)-7-ammonio-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• (7R)-7-amino-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-, (6R-trans)-
• 7-Amino-3-[[(2,5-dihydro-6-hydroxy-2-methyl-5-oxo-1,2,4-triazin-3-yl)thio]methyl]cephalosporanic acid
• (6R-trans)-7-Amino-8-oxo-3-(((1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio)methyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
• 7-AMINOCEPHALOSPORANIC TRIAZINE
• Ceftriaxone EP Impurity E
• (6R,7R)-7-amino-3-(((2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• Einecs 261-491-7
• DISCONTINUED
• (6R-trans)-7-amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid USP/EP/BP
• 7-Amino-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl
• 7-Amino-3-([2,5-dihydro-6-hydroxy-2-methyl-5-oxo-as-triazin-3-y]thiomethyl)-3-cephem-4-carboxylic acid
• Ceftriaxone Sodium Ep Impurity E
• Ceftriaxone impurity 4/Ceftriaxone EP Impurity E/7-AMino-3-[[(2,5-dihydro-6-hydroxy-2-Methyl-5-oxo-1,2,4-triazin-3-yl)thio]Methyl]cephalosporanic Acid
• Ceftriaxone Impurity E USP/EP/BP
• (7R)-7-amino-3-(((6-hydroxy-2-methyl-5-oxo-2,5-dihydro-1,2,4-triazin-3-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Ceftriaxone EP Impurity E

CAS: 58909-56-1

Fórmula: C₁₂H₁₃N₅O₅S₂

Forma y color: White To Off-White Solid

Peso molecular: 371.39

Ref: 4Z-C-936

7-Amino-3-[[(2,5-dihydro-6-hydroxy-2-methyl-5-oxo- 1,2,4-triazin-3-yl)thio]methyl]cephalosporanic acid

CAS: 58909-56-1

Ceftriaxone is a semisynthetic, broad-spectrum antibiotic that is used to treat bacterial infections. It is especially effective against the following microorganisms: Gram-positive cocci and rods, Gram-positive bacilli, Gram-negative cocci and rods, and anaerobic bacteria. Ceftriaxone is a crystalline solid that can be dissolved in water or an organic solvent. It has been shown to have excellent stability in acidic solutions and at high temperatures. Ceftriaxone has a residue of 3% when it is administered intravenously or intramuscularly. The use of ceftriaxone as an antibiotic can be optimized by using reverse-phase chromatography with a cyclic gradient elution method.

Fórmula: C₁₂H₁₃N₅O₅S₂

Pureza: 95%Nmr

Forma y color: Powder

Peso molecular: 371.39 g/mol

Ref: 3D-FA17508

Ceftriaxone EP Impurity E

CAS: 58909-56-1

Fórmula: C₁₂H₁₃N₅O₅S₂

Peso molecular: 371.39

Ref: ST-EA-CP-C91005