CAS 59-26-7

Tocainida

Descripción:

Tocainida es un compuesto farmacéutico utilizado principalmente como agente antiarrítmico, particularmente en el tratamiento de arritmias ventriculares. Pertenece a la clase de medicamentos conocidos como bloqueadores de canales de sodio, que actúan inhibiendo la entrada de iones de sodio durante la fase de despolarización del potencial de acción cardíaco, estabilizando así la membrana cardíaca y reduciendo la actividad eléctrica anormal. Tocainida se caracteriza por su fórmula química, que incluye un anillo de piperidina, y se administra típicamente por vía oral. La sustancia tiene una solubilidad moderada en agua y es conocida por su toxicidad relativamente baja en comparación con otros agentes antiarrítmicos. La farmacocinética de Tocainida implica metabolismo hepático, y se excreta principalmente a través de los riñones. Aunque es eficaz, su uso puede estar limitado por efectos secundarios como trastornos gastrointestinales y potenciales discrasias sanguíneas. Debido a estos factores, el monitoreo es esencial durante el tratamiento. En general, Tocainida representa una opción importante en el manejo de ciertas arritmias cardíacas, aunque su uso clínico ha disminuido con la llegada de nuevos agentes.

Fórmula: C₁₀H₁₄N₂O

InChI: InChI=1/C10H14N2O/c1-3-12(4-2)10(13)9-6-5-7-11-8-9/h5-8H,3-4H2,1-2H3

Clave InChI: InChIKey=NCYVXEGFNDZQCU-UHFFFAOYSA-N

SMILES: C(N(CC)CC)(=O)C=1C=CC=NC1

Sinónimos:

• Anacardone
• Astrocar
• Inicardio
• Kardiamid
• Leptamin
• Mediamid
• Niamine
• Nicamide
• Nicetamide
• Nicethamid
• Nicor
• Nicotinic Acid Diethyl Amide
• Nikethamide
• Nikotin
• N,N-diethyl-3-pyridinecarboxamide
• N,N-Diethylnicotinamide
• Percoral
• Procardine
• Pyridine-3-Carboxyldiethylamide
• Pyridine-3-Carboxylic Acid Diethylamide
• Reformin
• Salvacord
• Stellamine
• Stimulin
• Vasozol
• Diethyl-Nicotamide
• Dietilamide-Carbopiridina
• Dinacoryl
• Betapyrimidum
• Camphozone
• Cardiamid
• Cardiamine
• Cardamine
• Citocor
• Coracon
• Coraethamidum
• Coramine
• Corazone
• Cordiamin
• Cordynil
• Corediol
• Coretone
• Cormid
• Cornotone
• Corvitan
• Corvotone
• Danamine
• Elitone
• Hansacor
• N,N-diethylpyridine-3-carboxamide
• 3-(N,N-Diethylcarbamoyl)pyridine
• 3-Pyridinecarboxamide, N,N-diethyl-
• Anacordone
• Canfodiamina
• Carbamidal
• Cardiamide
• Cardimon
• Coractiv N
• Coramine (pharmaceutical)
• Cordiamine
• Cormed
• Cormotyl
• Corvin
• Corvitol
• Diethylnicotinamide
• Dynacoryl
• Ecoran
• Eucoran
• Kordiamin
• Nicetamida
• Nicethamide
• Ni-Cor
• Nicorine
• Nicotinamide, N,N-diethyl-
• Nicotinic acid diethylamide
• Nikardin
• Niketamide
• Niketamine
• Nikethamid
• Niketharol
• Nikethyl
• Nikorin
• Niquetamide
• Nsc 130820
• Nsc 169863
• Nsc 62103
• Pyricardyl
• Pyridine-3-carboxydiethylamide
• Rehormin
• Salvacard
• Sancora
• Solyacord
• Ventramine
• Nickethamide
• NIKETHAMIDUM
• LABOTEST-BB LT00134638

N,N-Diethylnicotinamide

CAS: 59-26-7

Fórmula: C₁₀H₁₄N₂O

Pureza: >98.0%(GC)(T)

Forma y color: White or Colorless to Light orange to Yellow powder to lump to clear liquid

Peso molecular: 178.24

Ref: 3B-D0514

NIKETHAMIDE CRS

CAS: 59-26-7

NIKETHAMIDE CRS

Fórmula: C₁₀H₁₄N₂O

Forma y color: May Be Present In Various Forms. Oily Liquid. Crystalline Mass. Yellow. Transparent.

Peso molecular: 178.231

Ref: 41-N0800000

Nikethamide

CAS: 59-26-7

Nikethamide is a stimulant which mainly influences the respiratory cycle. Widely known by its former sales name of Coramine, it was used in the mid-twentieth century as a medical countermeasure against tranquilizer overtreatments, before the advent of end

Fórmula: C₁₀H₁₄N₂O

Pureza: 99.42%

Forma y color: Followed By A Faint Sensation Of The Warmth (Ntp 1992)

Peso molecular: 178.23

Ref: TM-T0048

Nikethamide

CAS: 59-26-7

Fórmula: C₁₀H₁₄N₂O

Pureza: ≥ 98.0%

Forma y color: Colourless or pale yellow oily liquid, or crystalline mass

Peso molecular: 178.23

Ref: 7W-GP1304

Nikethamide, EP grade

CAS: 59-26-7

Fórmula: C₁₀H₁₄N₂O

Pureza: 99.0 - 101.0 % (anhydrous substance)

Forma y color: An oily liquid or a crystalline mass, colourless or pale yellow

Peso molecular: 178.23

Ref: 7W-GP1011

Nikethamide

CAS: 59-26-7

Forma y color: Neat

Ref: 04-C15525900

Nikethamide

CAS: 59-26-7

Forma y color: Neat

Ref: 61-FOR0627.00

Nikethamide

Producto controlado

CAS: 59-26-7

Fórmula: C₁₀H₁₄N₂O

Forma y color: Neat

Peso molecular: 178.23

Ref: 86-MM0627.00

N,N-Diethylnicotinamide

CAS: 59-26-7

N,N-Diethylnicotinamide

Pureza: 97%

Peso molecular: 178.23g/mol

Ref: 54-OR926552

N,N-Diethylnicotinamide (Nikethamide)

CAS: 59-26-7

Fórmula: C₁₀H₁₄N₂O

Peso molecular: 178.24

Ref: 4Z-N-133029

N,N-Diethylnicotinamide (Nikethamide)

CAS: 59-26-7

Applications Nikethamide is an analeptic agent. It was used in the mid-twentieth century as a medical countermeasure against tranquilizer overdoses, before the advent of endotracheal intubation and positive-pressure lung expansion. It is now considered to be of no value for such purposes, and may in fact be dangerous.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bean, J., et al.: Biochem. Pharm., 35, 1011 (1986); Chakaravarti, M.: J. Pharmacol., 67, 153 (1939); Naik, S., et al.: Biochem. Pharm., 18, 2038 (1969); Martindale, The Extra Pharmacopoeia, 30th ed,, 1229

Fórmula: C₁₀H₁₄N₂O

Forma y color: Off-White

Peso molecular: 178.23

Ref: TR-N460000

N,N-Diethylnicotinamide

Producto controlado

CAS: 59-26-7

N,N-Diethylnicotinamide is a nicotinamide derivative that is used as an anti-inflammatory agent. It has been shown to inhibit the activity of enzymes such as acetylcholinesterase, phospholipase A2, and cyclooxygenase. N,N-Diethylnicotinamide has a synergistic effect with pentobarbital sodium in inducing chronic pulmonary inflammation in rats. This drug also has an acid complexing effect on fatty acids and nitrogen atoms. The coordination geometry of this drug is octahedral with two nitrogen atoms coordinated to one metal ion. N,N-Diethylnicotinamide can be synthesized by reacting nicotinic acid with diethylamine in the presence of 1 equivalent of hydrogen gas.

Fórmula: C₁₀H₁₄N₂O

Pureza: Min. 95%

Forma y color: Colorless Clear Liquid

Peso molecular: 178.23 g/mol

Ref: 3D-FD31942

N,N-Diethylnicotinamide

CAS: 59-26-7

Fórmula: C₁₀H₁₄N₂O

Peso molecular: 178.24

Ref: ST-EA-CP-N35013