CAS 59-48-3

Oxindol

Descripción:

Oxindol es un compuesto orgánico caracterizado por su estructura bicíclica, que consiste en un anillo de indol fusionado a un grupo carbonilo. Es un sólido cristalino blanco a blanco sucio que es soluble en disolventes orgánicos como el etanol y el cloroformo, pero tiene una solubilidad limitada en agua. La fórmula molecular de Oxindol es C8H7NO, y presenta un átomo de nitrógeno dentro del marco del indol, lo que contribuye a sus propiedades básicas. Oxindol es conocido por su papel en diversas actividades biológicas, incluidas aplicaciones potenciales en farmacéuticos, donde sirve como un andamiaje para el desarrollo de medicamentos dirigidos a trastornos neurológicos y otras condiciones. Además, puede participar en diversas reacciones químicas, como sustituciones electrofílicas y ciclizaciones, lo que lo convierte en un intermediario valioso en la síntesis orgánica. Sus derivados han sido estudiados por sus propiedades antiinflamatorias, analgésicas y antitumorales, destacando la importancia del compuesto en la química medicinal. En general, Oxindol es un compuesto versátil con importantes implicaciones tanto en la investigación como en la industria.

Fórmula: C₈H₇NO

InChI: InChI=1S/C8H7NO/c10-8-5-6-3-1-2-4-7(6)9-8/h1-4H,5H2,(H,9,10)

Clave InChI: InChIKey=JYGFTBXVXVMTGB-UHFFFAOYSA-N

SMILES: O=C1CC=2C(N1)=CC=CC2

Sinónimos:

• 1,3-Dihydroindol-2-one
• 1,3-dihydro-2H-indol-2-one
• 2,3-Dihidroindol-2-Ona
• 2,3-Dihydro-1H-indol-2-one
• 2,3-Dihydroindol-2-One
• 2,3-Dihydroindol-2-on
• 2,3-Dihydroindole-2-One
• 2-Indolinone
• 2-Indolone
• 2-Oxindole
• 2-Oxo-2,3-dihydroindole
• 2-Oxoindole
• 2-Oxoindoline
• 2H-Indol-2-one, 1,3-dihydro-
• Indol-2(3H)-one
• Indolin-2-one
• Indoline-2-one
• Nsc 274863
• O-(Aminophenyl)Acetic acid Lactam
• Oxidinole (Indolin-2-One)
• Oxindol
• Timtec-Bb Sbb004215

Oxindole

CAS: 59-48-3

Fórmula: C₈H₇NO

Pureza: >98.0%(GC)

Forma y color: White to Light yellow to Light orange powder to crystal

Peso molecular: 133.15

Ref: 3B-O0272

Oxindole, 97+%

CAS: 59-48-3

Oxindole is considered as indole analogue, which shows pharmacological activity. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code

Fórmula: C₈H₇NO

Pureza: 97+%

Forma y color: White to dark cream to cream to brown, Powder

Peso molecular: 133.15

Ref: 02-A18764

1,3-Dihydro-2H-indol-2-one

CAS: 59-48-3

Forma y color: Neat

Ref: 61-FOR0006.02

Oxindole

CAS: 59-48-3

Lactams, nesoi

Fórmula: C₈H₇NO

Forma y color: White Crystalline Powder

Peso molecular: 133.05276

Ref: 45-1A09990

Indolin-2-One

CAS: 59-48-3

Fórmula: C₈H₇NO

Pureza: 98%

Forma y color: Solid

Peso molecular: 133.1473

Ref: IN-DA003R0B

Oxindole

CAS: 59-48-3

Oxindole (Indolin-2-one) is an aromatic heterocyclic building block.

Fórmula: C₈H₇NO

Pureza: 97.42% - 99.65%

Forma y color: Off-White Crystalline Powder

Peso molecular: 133.15

Ref: TM-Fr16741

2-Oxindole

CAS: 59-48-3

2-Oxindole

Fórmula: C₈H₇NO

Pureza: 98%

Forma y color: light orange powder

Peso molecular: 133.15g/mol

Ref: 54-OR30278

Oxindole

CAS: 59-48-3

Oxindole

Pureza: ≥95%

Peso molecular: 133.15g/mol

Ref: 54-BUP19393

Diclofenac EP Impurity E (Oxindole)

CAS: 59-48-3

Fórmula: C₈H₇NO

Forma y color: Brown Solid

Peso molecular: 133.15

Ref: 4Z-D-069

1,3-Dihydro-2H-indol-2-one

CAS: 59-48-3

Fórmula: C₈H₇NO

Forma y color: Neat

Peso molecular: 133.15

Ref: 86-MM0006.02

Oxindole

CAS: 59-48-3

Fórmula: C₈H₇NO

Pureza: (HPLC) ≥ 97.0%

Forma y color: White to light yellow or light orange crystalline powder

Peso molecular: 133.15

Ref: 7W-GK4423

Oxindole (2-Indolone)

Producto controlado

CAS: 59-48-3

Applications Indole analogue; shows pharmacological activity.
References Mohammadi, M., et al.: Science, 276, 955 (1997), Bramson, H., et al.: J. Med. Chem., 44, 4339 (2001), Lane, M., et al.: Cancer Res., 61, 6170 (2001), Yu, B., et al.: Biochem. Pharmacol., 64, 1091 (2002),

Fórmula: C₈H₇NO

Forma y color: Light Red

Peso molecular: 133.15

Ref: TR-I627300

Diclofenac EP Impurity E

CAS: 59-48-3

Fórmula: C₈H₇NO

Peso molecular: 133.15

Ref: ST-EA-CP-D20005

2-Indolone

CAS: 59-48-3

2-Indolone is a synthetic compound that belongs to the class of heterocyclic compounds. It is a trifluoroacetic acid derivative that has been shown to have potent antitumor activity, and it also inhibits cell proliferation. 2-Indolone has been shown to be an effective treatment for inflammatory diseases such as rheumatoid arthritis and Crohn's disease. This compound has been shown to bind to response elements in the promoter region of genes in the basic fibroblast line, and this binding leads to increased expression of gene products involved in inflammation and tumor suppression. The reaction mechanism for 2-indolone involves a two-step process, with activation energies for both steps being high. The first step involves protonation of the C2 hydroxyl group by trifluoroacetic acid, which leads to its displacement by hydrogen from water molecule H2O. In the second step, the oxindole ring opens up, with displacement of

Fórmula: C₈H₇NO

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 133.15 g/mol

Ref: 3D-FI24580

1,3-Dihydro-2H-indol-2-one

CAS: 59-48-3

Fórmula: C₈H₇NO

Pureza: 97%

Forma y color: Solid, Chunks or Crystalline Powder

Peso molecular: 133.15

Ref: 10-F093498

Oxindole

CAS: 59-48-3

Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases (RTKs) inhibitors such as SU4984 and intedanib, the RTK family represents an important therapeutic target for anti-cancer drug development.

Fórmula: C₈H₇NO

Pureza: 99.34%

Forma y color: Off-White Crystalline Powder

Peso molecular: 133.15

Ref: TM-FR16741