CAS 5909-24-0

Etil 4-cloro-2-(metiltio)-5-pirimidinacarboxilato

Descripción:

Etil 4-cloro-2-(metiltio)-5-pirimidinacarboxilato, con el número CAS 5909-24-0, es un compuesto químico que pertenece a la clase de los derivados de pirimidina. Presenta un anillo de pirimidina sustituido con un grupo cloro en la posición 4 y un grupo metiltio en la posición 2, junto con un grupo funcional de éster etílico en la posición del ácido carboxílico. Este compuesto se caracteriza típicamente por su solubilidad moderada a baja en agua, siendo más soluble en disolventes orgánicos como el etanol y el diclorometano. Su estructura sugiere una posible actividad biológica, lo que lo hace de interés en la investigación farmacéutica. La presencia de los sustituyentes cloro y metiltio puede influir en su reactividad e interacción con objetivos biológicos. Etil 4-cloro-2-(metiltio)-5-pirimidinacarboxilato puede ser sintetizado a través de diversas reacciones orgánicas, y sus derivados podrían exhibir diversas propiedades farmacológicas, incluyendo actividades antimicrobianas o antiinflamatorias. El manejo y almacenamiento adecuados son esenciales debido a su naturaleza química, y se deben consultar las hojas de datos de seguridad para obtener pautas específicas de seguridad.

Fórmula: C₈H₉ClN₂O₂S

InChI: InChI=1S/C8H9ClN2O2S/c1-3-13-7(12)5-4-10-8(14-2)11-6(5)9/h4H,3H2,1-2H3

Clave InChI: InChIKey=SNNHLSHDDGJVDM-UHFFFAOYSA-N

SMILES: C(OCC)(=O)C=1C(Cl)=NC(SC)=NC1

Sinónimos:

• 2-Methylthio-4-chloro-5-ethoxycarbonylpyrimidine
• 4-Chloro-2-(methylthio)-5-pyrimidinecarboxylic acid ethyl ester
• 4-Chloro-2-(methylthio)pyrimidin-5-carboxylic acid ethyl ester
• 4-Chloro-2-Methylthio-5-Pyrimidnecarboxylat
• 4-Chloro-2-methane-sulfanylpyrimidine-5-carboxylic Acid Ethyl Ester
• 4-Chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester
• 4-Chloro-2-methanethiopyrimidine-5-carboxylic acid ethyl ester
• 4-Chloro-2-methylsulfanyl-pyrimidine-5-carboxylic acid ethyl ester
• 4-Chloro-2-methylsulfanylpyrimidine-5-carboxylic acid ethyl ester
• 4-Chloro-2-methylthio-5-carbethoxypyrimidine
• 4-Chloro-5-Ethoxycarbonyl-2-Methylthiopyrimidine
• 4-Chloro-5-carbethoxy-2-methylthiopyrimidine
• 5-Pyrimidinecarboxylic acid, 4-chloro-2-(methylthio)-, ethyl ester
• Ethyl 4-Chloro-2-(Methylsulfanyl)Pyrimidine-5-Carboxylate
• Ethyl 4-Chloro2-methylthiopyrimidine-5-carboxylate
• Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate
• Ethyl 4-chloro-2-methylsulfanyl-5-pyrimidinecarboxylate
• Ethyl 4-chloro-2-methylthio-5-pyrimidine carboxylate
• Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate
• NSC 123534

Ethyl 4-Chloro-2-(methylthio)pyrimidine-5-carboxylate

CAS: 5909-24-0

Fórmula: C₈H₉ClN₂O₂S

Pureza: >97.0%(GC)

Forma y color: White to Orange to Green powder to crystal

Peso molecular: 232.68

Ref: 3B-E0841

Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate, 98%

CAS: 5909-24-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₈H₉ClN₂O₂S

Pureza: 98%

Forma y color: White to cream, powder

Peso molecular: 232.68

Ref: 02-B22429

Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate

CAS: 5909-24-0

Fórmula: C₈H₉ClN₂O₂S

Pureza: 96%

Forma y color: Solid

Peso molecular: 232.6873

Ref: IN-DA00371D

Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate

CAS: 5909-24-0

Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate

Fórmula: C₈H₉ClN₂O₂S

Pureza: 98%

Forma y color: colourless to faint yellow crystalline solid

Peso molecular: 232.69g/mol

Ref: 54-OR6605

Avanafil Impurity 61

CAS: 5909-24-0

Fórmula: C₈H₉ClN₂O₂S

Peso molecular: 232.68

Ref: 4Z-A-2967

Ethyl 4-chloro-2-methylthiopyrimidine-5-carboxylate

CAS: 5909-24-0

Fórmula: C₈H₉ClN₂O₂S

Pureza: 96%

Forma y color: Solid

Peso molecular: 232.68

Ref: 10-F005213

Ethyl 4-Chloro-2-methylthiopyrimidine-5-carboxylate

Producto controlado

CAS: 5909-24-0

Applications A pyrimidine derivative as inhibitor of Streptococcus faecium, Lactobacillus casei, and Pediococcus cerevisiae.
References Coats, E.A., et al.: Eur. J. Med. Chem., 14, 261 (1979),

Fórmula: C₈H₉ClN₂O₂S

Forma y color: Neat

Peso molecular: 232.69

Ref: TR-E902000

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate

CAS: 5909-24-0

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate is a potent inhibitor of tyrosine kinases. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. This drug has also been shown to be effective against various types of human cancer cell lines, such as human leukemia cells and myeloma cells. Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate inhibits the production of proteins vital for cell division by binding to tyrosine kinase. This binding prevents the formation of an enzyme complex with other enzymes that are required for protein synthesis, thereby inhibiting protein synthesis and cell division. The compound has also been shown to be a highly selective inhibitor of amines, which may contribute to its pharmacological effects.

Fórmula: C₈H₉ClN₂O₂S

Pureza: Min. 95%

Peso molecular: 232.69 g/mol

Ref: 3D-FE15899

Avanafil Impurity 61

CAS: 5909-24-0

Fórmula: C₈H₉ClN₂O₂S

Peso molecular: 232.68

Ref: ST-EA-CP-A84036