CAS 59122-46-2

Misoprostol

Descripción:

Misoprostol es un análogo sintético de la prostaglandina E1, utilizado principalmente en medicina por su capacidad para inducir contracciones uterinas y proteger la mucosa gástrica. Se caracteriza por su forma de polvo cristalino blanco a blanco sucio, que es soluble en agua y en disolventes orgánicos como el etanol. Misoprostol actúa uniéndose a los receptores de prostaglandinas, lo que lleva a varios efectos fisiológicos, incluyendo la estimulación de contracciones uterinas, maduración cervical e inhibición de la secreción de ácido gástrico. Sus aplicaciones terapéuticas incluyen la prevención de úlceras gástricas en pacientes que toman medicamentos antiinflamatorios no esteroides (AINEs), así como su uso en obstetricia y ginecología para el aborto médico y la gestión del aborto espontáneo. El compuesto se administra típicamente por vía oral o vaginal, y su farmacocinética implica una rápida absorción y metabolismo, con una vida media relativamente corta. El perfil de seguridad de Misoprostol es generalmente favorable, pero puede causar efectos secundarios como trastornos gastrointestinales y hiperestimulación uterina, lo que requiere un monitoreo cuidadoso durante su uso.

Fórmula: C₂₂H₃₈O₅

InChI: InChI=1/C22H38O5/c1-4-5-14-22(2,26)15-10-12-18-17(19(23)16-20(18)24)11-8-6-7-9-13-21(25)27-3/h10,12,17-18,20,24,26H,4-9,11,13-16H2,1-3H3/b12-10+/t17-,18-,20-,22?/s2

Clave InChI: InChIKey=OJLOPKGSLYJEMD-YUQTXCCYNA-N

SMILES: C(=C/CC(CCCC)(C)O)\[C@@H]1[C@@H](CCCCCCC(OC)=O)C(=O)C[C@H]1O

Sinónimos:

• (+-)-Methyl (1R,2R,3R)-3-hydroxy-2-((E)-(4RS)-4-hydroxy-4-methyl-1-octenyl)-5-oxocyclopentaneheptanoate
• (11a,13E)-(±)-11,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic Acid Methyl Ester
• (11alpha,13E)-(+)-11alpha,16-Dihydroxy-16-methyl-9-oxoprost-13E-en-1-oic acid methyl ester
• (±)-15-Deoxy-(16RS)-16-hydroxy-16-methyl-PGE1 Methyl Ester
• Cytotec
• Isprelor
• Misogon
• Misoprost
• Misoprostil
• Misotac
• Prost-13-en-1-oic acid, 11,16-dihydroxy-16-methyl-9-oxo-, methyl ester, (11α,13E)-
• Sc 29333
• methyl (11alpha,13E)-11-hydroxy-16,16-dimethyl-9-oxoprost-13-en-1-oate
• methyl (11alpha,13E,16S)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate

MISOPROSTOL FOR SYSTEM SUITABILITY CRS

CAS: 59122-46-2

MISOPROSTOL FOR SYSTEM SUITABILITY CRS

Fórmula: C₂₂H₃₈O₅

Peso molecular: 382.5341

Ref: 41-Y0001162

MISOPROSTOL CRS

CAS: 59122-46-2

MISOPROSTOL CRS

Forma y color: Added Added

Ref: 41-Y0000490

Misoprostol

CAS: 59122-46-2

Prostaglandins, thromboxanes and leukotrienes, their derivatives and structural analogues

Fórmula: C₂₂H₃₈O₅

Forma y color: Colorless Light Yellow Liquid Viscous

Peso molecular: 382.27192

Ref: 45-1444300

Misoprostol

CAS: 59122-46-2

Misoprostol, a prostaglandin E1 derivative, has a strong inhibitory effect on gastric acid secretion, while having a contractile effect on pregnancy.

Fórmula: C₂₂H₃₈O₅

Pureza: 99.78%

Forma y color: Water-Soluble Viscous Liquid

Peso molecular: 382.53

Ref: TM-T2573

Misoprostol (0.10% wt/v in METHYL ACETATE), min. 97%

CAS: 59122-46-2

Fórmula: C₂₂H₃₈O₅

Pureza: min. 97%

Forma y color: White to Yellowish Oil (SOLUTION IN 10% METHYL ACETATE)

Peso molecular: 382.53

Ref: 08-06-6006

Misoprostol (Mixture of Diastereomers)

CAS: 59122-46-2

Fórmula: C₂₂H₃₈O₅

Forma y color: Pale Yellow Oil

Peso molecular: 382.54

Ref: 4Z-M-2314

Misoprostol-d5 (Mixture of Diastereomers)

CAS: 59122-46-2

Fórmula: C₂₂H₃₃D₅O₅

Peso molecular: 387.58

Ref: 4Z-M-2310

Misoprostol

CAS: 59122-46-2

Fórmula: C₂₂H₃₈O₅

Pureza: ≥ 99.0%

Forma y color: Colourless to light yellow liquid

Peso molecular: 382.53

Ref: 7W-GP2918

Misoprostol

CAS: 59122-46-2

Misoprostol

Pureza: 1%

Peso molecular: 382.54g/mol

Ref: 54-OR1030918

Misoprostol

Producto controlado

CAS: 59122-46-2

Applications Misoprostol is a cytoprotective prostaglandin PGE1 analogue.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Graham, Y., et al.: Lancet, 2, 1277 (1988); Graham, D.Y., et al.: Ann. Int. Med., 119, 257 (1993); Fletcher, H., et al.: Obstet. Gynecol., 83, 244 (1994);

Fórmula: C₂₂H₃₈O₅

Forma y color: Light Yellow Viscous

Peso molecular: 382.53

Ref: TR-M368755

Misoprostol, 1% in cellulose

Producto controlado

CAS: 59122-46-2

Fórmula: C₂₂H₃₈O₅

Forma y color: Single Solution

Peso molecular: 382.53

Ref: TR-M368750

Misoprostol - 1% in cellulose

Producto controlado

CAS: 59122-46-2

Misoprostol is a nonsteroidal anti-inflammatory drug that is used for the treatment of dysmenorrhea and chronic non-specific low back pain. Misoprostol is also used in nephrology dialysis to decrease blood pressure, heart rate, and fluid retention in patients with congestive heart failure. It has been shown that misoprostol can be used to prevent preterm labor in pregnant women with a statistically significant reduction in the risk of miscarriage, preterm birth, and neonatal death. It has been shown that misoprostol can be administered orally or vaginally for the prevention of preterm labor. The pharmacokinetic properties of misoprostol are dose-dependent; higher doses result in faster absorption. Clinical relevance is dependent on the concentration-time curve, which determines how quickly the drug reaches its peak concentration. The clinical relevance of misoprostol is determined by the dose group (low dose or high dose), as well as diastolic

Fórmula: C₂₂H₃₈O₅

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 382.53 g/mol

Ref: 3D-FM26017

Misoprostol

Producto controlado

CAS: 59122-46-2

Misoprostol is a prostaglandin E1 analogue that is used for the prevention and treatment of peptic ulcers. It also has been shown to reduce the risk of gastric cancer in the general population, although this effect may be limited to patients with a history of nonsteroidal anti-inflammatory drug use. Misoprostol has been found to be more effective in women who have already given birth than in those who have not, with a statistically significant reduction in the incidence of pregnancy during long-term use. Misoprostol is metabolized by cytochrome P450 enzymes and excreted primarily through the kidneys. The drug's pharmacokinetic properties are dependent on diastolic blood pressure, body mass index, and levels of blood sampling. Intrauterine placement can also increase its efficacy as it bypasses first-pass metabolism.

Fórmula: C₂₂H₃₈O₅

Pureza: Min. 95%

Forma y color: Colorless Clear Liquid

Peso molecular: 382.53 g/mol

Ref: 3D-FM46798