CAS 59122-46-2
:Misoprostol
Descripción:
Misoprostol es un análogo sintético de la prostaglandina E1, utilizado principalmente en medicina por su capacidad para inducir contracciones uterinas y proteger la mucosa gástrica. Se caracteriza por su forma de polvo cristalino blanco a blanco sucio, que es soluble en agua y en disolventes orgánicos como el etanol. Misoprostol actúa uniéndose a los receptores de prostaglandinas, lo que lleva a varios efectos fisiológicos, incluyendo la estimulación de contracciones uterinas, maduración cervical e inhibición de la secreción de ácido gástrico. Sus aplicaciones terapéuticas incluyen la prevención de úlceras gástricas en pacientes que toman medicamentos antiinflamatorios no esteroides (AINEs), así como su uso en obstetricia y ginecología para el aborto médico y la gestión del aborto espontáneo. El compuesto se administra típicamente por vía oral o vaginal, y su farmacocinética implica una rápida absorción y metabolismo, con una vida media relativamente corta. El perfil de seguridad de Misoprostol es generalmente favorable, pero puede causar efectos secundarios como trastornos gastrointestinales y hiperestimulación uterina, lo que requiere un monitoreo cuidadoso durante su uso.
Fórmula:C22H38O5
InChI:InChI=1/C22H38O5/c1-4-5-14-22(2,26)15-10-12-18-17(19(23)16-20(18)24)11-8-6-7-9-13-21(25)27-3/h10,12,17-18,20,24,26H,4-9,11,13-16H2,1-3H3/b12-10+/t17-,18-,20-,22?/s2
Clave InChI:InChIKey=OJLOPKGSLYJEMD-YUQTXCCYNA-N
SMILES:C(=C/CC(CCCC)(C)O)\[C@@H]1[C@@H](CCCCCCC(OC)=O)C(=O)C[C@H]1O
Sinónimos:- (+-)-Methyl (1R,2R,3R)-3-hydroxy-2-((E)-(4RS)-4-hydroxy-4-methyl-1-octenyl)-5-oxocyclopentaneheptanoate
- (11a,13E)-(±)-11,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic Acid Methyl Ester
- (11alpha,13E)-(+)-11alpha,16-Dihydroxy-16-methyl-9-oxoprost-13E-en-1-oic acid methyl ester
- (±)-15-Deoxy-(16RS)-16-hydroxy-16-methyl-PGE1 Methyl Ester
- Cytotec
- Isprelor
- Misogon
- Misoprost
- Misoprostil
- Misotac
- Prost-13-en-1-oic acid, 11,16-dihydroxy-16-methyl-9-oxo-, methyl ester, (11α,13E)-
- Sc 29333
- methyl (11alpha,13E)-11-hydroxy-16,16-dimethyl-9-oxoprost-13-en-1-oate
- methyl (11alpha,13E,16S)-11,16-dihydroxy-16-methyl-9-oxoprost-13-en-1-oate
- Ver más sinónimos
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Encontrado 13 productos.
MISOPROSTOL FOR SYSTEM SUITABILITY CRS
CAS:MISOPROSTOL FOR SYSTEM SUITABILITY CRSFórmula:C22H38O5Peso molecular:382.5341Misoprostol
CAS:Prostaglandins, thromboxanes and leukotrienes, their derivatives and structural analoguesFórmula:C22H38O5Forma y color:Colorless Light Yellow Liquid ViscousPeso molecular:382.27192Misoprostol
CAS:Misoprostol, a prostaglandin E1 derivative, has a strong inhibitory effect on gastric acid secretion, while having a contractile effect on pregnancy.Fórmula:C22H38O5Pureza:99.78%Forma y color:Water-Soluble Viscous LiquidPeso molecular:382.53Misoprostol (0.10% wt/v in METHYL ACETATE), min. 97%
CAS:Fórmula:C22H38O5Pureza:min. 97%Forma y color:White to Yellowish Oil (SOLUTION IN 10% METHYL ACETATE)Peso molecular:382.53Misoprostol (Mixture of Diastereomers)
CAS:Fórmula:C22H38O5Forma y color:Pale Yellow OilPeso molecular:382.54Misoprostol
CAS:Fórmula:C22H38O5Pureza:≥ 99.0%Forma y color:Colourless to light yellow liquidPeso molecular:382.53Misoprostol
CAS:Producto controlado<p>Applications Misoprostol is a cytoprotective prostaglandin PGE1 analogue.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Graham, Y., et al.: Lancet, 2, 1277 (1988); Graham, D.Y., et al.: Ann. Int. Med., 119, 257 (1993); Fletcher, H., et al.: Obstet. Gynecol., 83, 244 (1994);<br></p>Fórmula:C22H38O5Forma y color:Light Yellow ViscousPeso molecular:382.53Misoprostol, 1% in cellulose
CAS:Producto controladoFórmula:C22H38O5Forma y color:Single SolutionPeso molecular:382.53Misoprostol - 1% in cellulose
CAS:Producto controlado<p>Misoprostol is a nonsteroidal anti-inflammatory drug that is used for the treatment of dysmenorrhea and chronic non-specific low back pain. Misoprostol is also used in nephrology dialysis to decrease blood pressure, heart rate, and fluid retention in patients with congestive heart failure. It has been shown that misoprostol can be used to prevent preterm labor in pregnant women with a statistically significant reduction in the risk of miscarriage, preterm birth, and neonatal death. It has been shown that misoprostol can be administered orally or vaginally for the prevention of preterm labor. The pharmacokinetic properties of misoprostol are dose-dependent; higher doses result in faster absorption. Clinical relevance is dependent on the concentration-time curve, which determines how quickly the drug reaches its peak concentration. The clinical relevance of misoprostol is determined by the dose group (low dose or high dose), as well as diastolic</p>Fórmula:C22H38O5Pureza:Min. 95%Forma y color:PowderPeso molecular:382.53 g/molMisoprostol
CAS:Producto controlado<p>Misoprostol is a prostaglandin E1 analogue that is used for the prevention and treatment of peptic ulcers. It also has been shown to reduce the risk of gastric cancer in the general population, although this effect may be limited to patients with a history of nonsteroidal anti-inflammatory drug use. Misoprostol has been found to be more effective in women who have already given birth than in those who have not, with a statistically significant reduction in the incidence of pregnancy during long-term use. Misoprostol is metabolized by cytochrome P450 enzymes and excreted primarily through the kidneys. The drug's pharmacokinetic properties are dependent on diastolic blood pressure, body mass index, and levels of blood sampling. Intrauterine placement can also increase its efficacy as it bypasses first-pass metabolism.</p>Fórmula:C22H38O5Pureza:Min. 95%Forma y color:Colorless Clear LiquidPeso molecular:382.53 g/mol
