CAS 59736-84-4

MtbHU-IN-1

CAS: 59736-84-4

MtbHU-IN-1 is a Mycobacterium tuberculosis nucleoid-associated protein HU (MtbHU)inhibitor(binding to WT MtbHU with a Kd of 98 nM).

Fórmula: C₄₄H₃₆N₄O₁₂S₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 876.91

Ref: TM-T12121

MtbHU-IN-1

CAS: 59736-84-4

MtbHU-IN-1 is a small-molecule inhibitor designed specifically for targeting the HU protein in Mycobacterium tuberculosis. This compound is derived through rational drug design and computational modeling efforts, exploiting the vulnerabilities of the bacterial DNA-binding proteins. Its mode of action involves binding to the HU protein, inhibiting its function, which is crucial for DNA structuring and stability within the bacterial cell. By disrupting HU protein function, MtbHU-IN-1 impairs bacterial chromosomal architecture, leading to an inability to replicate and ultimately cell death.

Fórmula: C₄₄H₃₆N₄O₁₂S₂

Pureza: Min. 95%

Peso molecular: 876.9 g/mol

Ref: 3D-JCA73684