CAS 5988-19-2

Ácido L-dihidoroótico

Descripción:

Ácido L-dihidoroótico, con el número CAS 5988-19-2, es un derivado de pirimidina que juega un papel crucial en la biosíntesis de nucleótidos, específicamente en la vía de síntesis de novo de pirimidinas. Es un sólido cristalino blanco a blanco sucio que es soluble en agua y exhibe una naturaleza ligeramente ácida. El compuesto se caracteriza por su capacidad para sufrir oxidación y formar ácido orótico, que es un precursor importante en la síntesis de ácidos nucleicos. Ácido L-dihidoroótico está involucrado en varios procesos biológicos, incluyendo el metabolismo celular y la regulación del crecimiento celular. Su fórmula estructural incluye un grupo de ácido dihidroorótico, que presenta un anillo de pirimidina con dos grupos de ácido carboxílico. Este compuesto es de interés en farmacología y bioquímica, particularmente por sus posibles aplicaciones terapéuticas en condiciones relacionadas con el metabolismo de nucleótidos. Además, sirve como sustrato para enzimas como la dihidroorotato deshidrogenasa, que es un objetivo para ciertos fármacos anticancerígenos e inmunosupresores.

Fórmula: C₅H₆N₂O₄

InChI: InChI=1/C5H6N2O4/c8-3-1-2(4(9)10)6-5(11)7-3/h2H,1H2,(H,9,10)(H2,6,7,8,11)/t2-/m0/s1

Clave InChI: InChIKey=UFIVEPVSAGBUSI-REOHCLBHSA-N

SMILES: C(O)(=O)[C@@H]1CC(=O)NC(=O)N1

Sinónimos:

• (4S)-2,6-Dioxo-1,3-diazinane-4-carboxylic acid
• (4S)-Hexahydro-2,6-dioxo-4-pyrimidinecarboxylic acid
• (S)-2,6-Dioxohexahydropyrimidine-4-carboxylic acid
• 4-Pyrimidinecarboxylic acid, hexahydro-2,6-dioxo-, (4S)-
• 4-Pyrimidinecarboxylic acid, hexahydro-2,6-dioxo-, (S)-
• <span class="text-smallcaps">L</span>-5,6-Dihydroorotic acid
• <span class="text-smallcaps">L</span>-Dihydroorotate
• <span class="text-smallcaps">L</span>-Dihydroorotic acid
• Hydroorotic acid, <span class="text-smallcaps">L</span>-
• L-Dihydroorotic acid
• Hydroorotic acid, L-
• L-Dihydroorotate
• Adenosine-5'-diphosphoric acid Na2
• Guanosine-5-diphosphate disodiun
• 2,6-Dioxohexahydro-4-pyrimidinecarboxylic acid
• Guanosine-5-monophosphate disodiun
• Adenosine-5-triphosphoric acid Na2
• Deoxyribonucein acid(fish sperm)
• DIHYDRO-L-OROTIC ACID
• Guanosine-5'-triphosphate disodiun
• Inosine-5-triphosphate trisodium
• L-HYDROOROTIC ACID
• Ribonuclein acid,yeast
• (S)-2,6-Dioxohexahydro-4-pyrimidinecarboxylic acid
• (S)-(+)-HYDROOROTIC ACID
• L-4,5-Dihydroorotic acid~(S)-(+)-2,6-Dioxohexahydro-4-pyrimidinecarboxylic acid
• t-Ribonuclein acid,yeast
• (S)-Dihydroorotate

L-Dihydroorotic acid, 98%

CAS: 5988-19-2

L-Dihydroorotic acid a metabolite. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of

Fórmula: C₅H₆N₂O₄

Pureza: 98%

Peso molecular: 158.11

Ref: 02-H60429

(4S)-2,6-dioxo-1,3-diazinane-4-carboxylic acid

CAS: 5988-19-2

Fórmula: C₅H₆N₂O₄

Pureza: 97%

Forma y color: Solid

Peso molecular: 158.1121

Ref: IN-DA00IAMJ

L-Dihydroorotic acid

CAS: 5988-19-2

L-Dihydroorotic acid

Pureza: ≥98%

Peso molecular: 158.11g/mol

Ref: 54-BUP14613

L-Dihydro-Orotic Acid

CAS: 5988-19-2

Fórmula: C₅H₆N₂O₄

Peso molecular: 158.11

Ref: 4Z-O-031007

L-Dihydroorotic Acid

CAS: 5988-19-2

L-Dihydroorotic Acid

Pureza: 98%

Peso molecular: 158.11g/mol

Ref: 54-OR1013652

L-Dihydroorotic acid

CAS: 5988-19-2

L-Dihydroorotic acid, found in eukaryotes, is involved in pyrimidine metabolism and several disorders including orotic aciduria.

Fórmula: C₅H₆N₂O₄

Pureza: 99.88% - 99.93%

Forma y color: White To Off-White Crystalline Powder

Peso molecular: 158.11

Ref: TM-T4880

L-Dihydroorotic acid

Producto controlado

CAS: 5988-19-2

Applications L-Dihydroorotic acid is used as a reactant in the preparation of long acting Gonadotrophin-releasing hormone (GnRH) antagonist containing p-ureido-phenylalanine.
References Jiang, G., et al.: J. Med. Chem., 44, 453 (2001);

Fórmula: C₅H₆N₂O₄

Forma y color: Neat

Peso molecular: 158.11

Ref: TR-D451530

L-Dihydroorotic acid

CAS: 5988-19-2

L-Dihydroorotic acid is a natural compound that can be found in plants, animals and humans. It has been shown to have an important role in mitochondrial functions, as it is involved in the synthesis of NADH and ATP. L-Dihydroorotic acid can also be used as a substrate for enzymatic reactions, such as dehydrogenase or dihydroorotate dehydrogenase. The rate constants for these reactions are high, which makes L-dihydroorotic acid a good model system for studying biochemical properties. L-dihydroorotic acid also inhibits cyclin D2/CDK4 protein kinases.

Fórmula: C₅H₆N₂O₄

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 158.11 g/mol

Ref: 3D-FD33036

L-Dihydroorotic acid

CAS: 5988-19-2

Fórmula: C₅H₆N₂O₄

Pureza: 97%

Forma y color: Solid

Peso molecular: 158.113

Ref: 10-F049588