CAS 60-54-8

(-)-Tetraciclina

Descripción:

(-)-Tetraciclina es un antibiótico de amplio espectro que pertenece a la clase de las tetraciclinas, caracterizado por su capacidad para inhibir la síntesis de proteínas bacterianas. Se deriva de la bacteria Streptomyces aureofaciens y es conocido por su efectividad contra una amplia gama de bacterias grampositivas y gramnegativas. La estructura química de (-)-Tetraciclina presenta un sistema de cuatro anillos con múltiples grupos funcionales, incluidos grupos hidroxilo y dimetilamina, que contribuyen a su solubilidad y actividad biológica. Este compuesto exhibe propiedades como buena biodisponibilidad oral y una vida media relativamente larga, lo que permite regímenes de tratamiento efectivos. (-)-Tetraciclina también es conocido por sus posibles efectos secundarios, incluidos trastornos gastrointestinales y fotosensibilidad. Además, se ha utilizado en diversas aplicaciones más allá de la medicina humana, incluida la medicina veterinaria y la agricultura, particularmente en el tratamiento de infecciones y como promotor del crecimiento en el ganado. Su mecanismo de acción implica principalmente la unión a la subunidad ribosomal 30S, impidiendo así la unión de aminoacil-tRNA e inhibiendo la síntesis de proteínas en las bacterias.

Fórmula: C₂₂H₂₄N₂O₈

InChI: InChI=1S/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30)/t9-,10-,15-,21+,22-/m0/s1

Clave InChI: InChIKey=OFVLGDICTFRJMM-WESIUVDSSA-N

SMILES: O[C@@]12[C@@](C[C@]3(C(=C1O)C(=O)C=4C([C@@]3(C)O)=CC=CC4O)[H])([C@H](N(C)C)C(O)=C(C(N)=O)C2=O)[H]

Sinónimos:

• (4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide
• (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
• (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride (1:1)
• (4S,4aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aS,5aS,6S,12aS)-
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, [4S-(4α,4aα,5aα,6β,12aα)]-
• 4-(Dimethylamino)-3,6,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide
• 6-Methyl-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide
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Tetracycline Hydrochloride

CAS: 60-54-8, 64-75-5

Fórmula: C₂₂H₂₄N₂O₈·HCl

Pureza: >98.0%(T)

Forma y color: Light yellow to Amber to Dark green powder to crystal

Peso molecular: 480.90

Ref: 3B-T2525

Tetracycline

CAS: 60-54-8

Fórmula: C₂₂H₂₄N₂O₈

Pureza: >95.0%(T)(HPLC)

Forma y color: Light yellow to Yellow powder to crystal

Peso molecular: 444.44

Ref: 3B-T3971

Tetracycline

CAS: 60-54-8

Tetracycline, 60-54-8, is a broad-spectrum napthacene antibiotic which inhibits bacterial protein synthesis by binding the 30S ribosomal subunit. Learn more.

Fórmula: C₂₂H₂₄N₂O₈

Forma y color: Yellow to orange to brown, Crystalline powder or powder

Peso molecular: 444.44

Ref: 02-J61714

Tetracycline

CAS: 60-54-8

Tetracycline (Tetracyclin) is a broad-spectrum antibiotic. Tetracycline is commonly used in anti-infective studies. Cost-effective and quality-assured.

Fórmula: C₂₂H₂₄N₂O₈

Pureza: 92.65% - 98.18%

Forma y color: Light Yellow Crystal

Peso molecular: 444.43

Ref: TM-T0912L

(4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide

CAS: 60-54-8

Fórmula: C₂₂H₂₄N₂O₈

Pureza: 96%

Forma y color: Solid

Peso molecular: 444.4346

Ref: IN-DA003UNG

Tetracycline, EP grade

CAS: 60-54-8

Fórmula: C₂₂H₂₄N₂O₈

Pureza: 88.0 - 102.0 % (dried basis)

Forma y color: Yellow crystalline powder

Peso molecular: 444.43

Ref: 7W-GA0548

Tetracycline

CAS: 60-54-8

Tetracycline

Pureza: ≥80%

Peso molecular: 444.43g/mol

Ref: 54-BUP17381

Tetracycline-13C2-d6 (Oxytetracycline EP Impurity B-13C2-d6)

CAS: 60-54-8

Fórmula: C₂₀₁₃C₂H₁₈D₆N₂O₈

Peso molecular: 452.46

Ref: 4Z-T-4027

Tetracycline base

CAS: 60-54-8

Fórmula: C₂₂H₂₄N₂O₈·xH₂O

Pureza: ≥ 91.0%

Forma y color: Light-yellow to dark yellow powder

Peso molecular: 444.43 (anhydrous)

Ref: 7W-GA9779

Tetracycline 13C22,15N2 dried down 2.5 µg/mL

Producto controlado

CAS: 60-54-8

Fórmula: C₂₂H₂₄₁₅N₂O₈

Forma y color: Single Solution

Peso molecular: 468.26

Ref: 04-S17396147DD-2.5

Tetracycline dried down 2.5 µg/mL

Producto controlado

CAS: 60-54-8

Fórmula: C₂₂H₂₄N₂O₈

Forma y color: Single Solution

Peso molecular: 444.43

Ref: 04-A17396145DD-2.5

Tetracycline (Oxytetracycline EP Impurity B)

CAS: 60-54-8

Fórmula: C₂₂H₂₄N₂O₈

Peso molecular: 444.45

Ref: 4Z-T-4030

Tetracycline

CAS: 60-54-8

Impurity Oxytetracycline Hydrochloride EP Impurity B
Applications Tetracycline is a compound that has been shown to induce apoptosis in various cells. Tetracycline was a useful compound to study drug resistance of pathogens of infections in patients with severe liver disease.
References Yao, L., et al.: Zhongguo Linchuang Yanjiu, 29, 1510 (2016)

Fórmula: C₂₂H₂₄N₂O₈

Forma y color: Yellow

Peso molecular: 444.43

Ref: TR-T291413

Tetracycline - Bio-X ™

CAS: 60-54-8

Tetracycline is a broad-spectrum antibiotic that is effective against a variety of bacterial infections. It is a polyketide antibiotic that inhibits protein synthesis by binding to ribosomes and preventing the attachment of amino acids to tRNA molecules thus inhibiting bacterial growth.

Fórmula: C₂₂H₂₄N₂O₈

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 444.43 g/mol

Ref: 3D-BT166207

Tetracycline

CAS: 60-54-8

Antibiotic of tetracycline class; protein synthesis inhibitor

Fórmula: C₂₂H₂₄N₂O₈

Pureza: Min. 91 Area-%

Forma y color: Powder

Peso molecular: 444.43 g/mol

Ref: 3D-AT35208

(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-6,10,12,12a-tetrahydroxy-6-methyl-1,3,11-trioxo-1,2,3,4,4a,5,5a,6,11,12a-decahydrotetracene-2-carboxamide

CAS: 60-54-8

Pureza: 96%

Peso molecular: 444.4400024

Ref: 10-F862906

Lymecycline EP Impurity H

CAS: 60-54-8

Fórmula: C₂₂H₂₄N₂O₈

Peso molecular: 444.44

Ref: ST-EA-CP-L64008

Tetracycline-d6

CAS: 60-54-8

Tetracycline-d6 is an antibiotic that inhibits the growth of bacteria by binding to the ribosomal subunit. Tetracycline-d6 is used in the treatment of urinary infections caused by E. coli, Enterobacter cloacae, Klebsiella pneumoniae, and Proteus mirabilis. Tetracycline-d6 has been shown to have antimicrobial activity against a wide range of microorganisms including gram negative and gram positive bacteria, as well as fungi and protozoa. It has been shown to be active against methicillin resistant strains such as S. aureus (MRSA), with an antibacterial efficacy comparable to that of erythromycin. The tetracycline resistance gene is located on plasmids and can be transferred between bacterial cells through conjugation or transduction. Tetracycline-d6 is often used in combination with beta lactam antibiotics such as pen

Pureza: Min. 95%

Ref: 3D-FT180092