CAS 604-59-1

Alfa-naftoflavona

Descripción:

Alfa-naftoflavona, con el número CAS 604-59-1, es un compuesto orgánico que pertenece a la clase de los flavonoides. Se caracteriza por su estructura policíclica, que consiste en una porción de flavona fusionada a un sistema de anillo de naftaleno. Este compuesto típicamente aparece como un sólido cristalino de color amarillo a naranja y es conocido por su solubilidad en disolventes orgánicos como el etanol y el dimetilsulfóxido, pero es menos soluble en agua. Alfa-naftoflavona exhibe diversas actividades biológicas, incluyendo propiedades antioxidantes y la capacidad de modular la actividad enzimática, particularmente en relación con las enzimas del citocromo P450. Se ha estudiado por sus posibles efectos en el metabolismo de ciertos fármacos y su papel en la activación de diversas vías de señalización. Además, se ha utilizado en investigaciones para investigar los mecanismos de acción relacionados con la carcinogénesis y los efectos de los contaminantes ambientales. Los datos de seguridad indican que, aunque puede presentar algunos peligros, generalmente se maneja con precauciones estándar de laboratorio.

Fórmula: C₁₉H₁₂O₂

InChI: InChI=1/C19H12O2/c20-17-12-18(14-7-2-1-3-8-14)21-19-15-9-5-4-6-13(15)10-11-16(17)19/h1-12H

Clave InChI: InChIKey=VFMMPHCGEFXGIP-UHFFFAOYSA-N

SMILES: O=C1C=2C(=C3C(=CC2)C=CC=C3)OC(=C1)C4=CC=CC=C4

Sinónimos:

• 2-Phenyl-4H-naphtho[1,2-b]pyran-4-one
• 2-Phenylbenzo(H)Chromen-4-One
• 2-phenyl-4H-benzo[h]chromen-4-one
• 4H-Naphtho[1,2-b]pyran-4-one, 2-phenyl-
• 7,8-Benzoflavone
• Benzo[h]flavone
• NSC 407011
• Uccf 023
• α-Naphthoflavone
• α-Naphthylflavone
• -Naphthoflavone
• 2-b)pyran-4-one,2-phenyl-4h-naphtho(
• BENZOFLAVONE
• NAPHTHOFLAVANONE, A-
• 1-Naphthoflavone
• alpha-naphthylflavone
• NAPHTHOFLAVONE, A-
• ALPHA-NAPHTHOFLAVONE REDOX INDICATOR
• alpha-Naphthoflavone,97%
• 2-b]pyran-4-one,2-phenyl-4h-naphtho[
• A-NAPHTHOFLAVANONE
• alfa-Naphthoflavone

α-Naphthoflavone

CAS: 604-59-1

Fórmula: C₁₉H₁₂O₂

Pureza: >98.0%(HPLC)

Forma y color: White to Yellow to Orange powder to crystal

Peso molecular: 272.30

Ref: 3B-B0056

α-Naphthoflavone, 97%

CAS: 604-59-1

An aryl hydrocarbon receptor antagonist This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a pa

Fórmula: C₁₉H₁₂O₂

Pureza: 97%

Forma y color: White to pale cream, Powder

Peso molecular: 272.30

Ref: 02-A18542

7,8-Benzoflavone

CAS: 604-59-1

7,8-Benzoflavone analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Fórmula: C₁₉H₁₂O₂

Pureza: (HPLC) ≥95%

Forma y color: Powder

Peso molecular: 272.31

Ref: 11-1008

2-Phenyl-4H-benzo[h]chromen-4-one

CAS: 604-59-1

Fórmula: C₁₉H₁₂O₂

Pureza: 98%

Forma y color: Solid

Peso molecular: 272.2974

Ref: IN-DA003VG1

α-Naphthoflavone

CAS: 604-59-1

Fórmula: C₁₉H₁₂O₂

Peso molecular: 272.31

Ref: 7W-GK0485

α-Naphthoflavone

CAS: 604-59-1

α-Naphthoflavone

Pureza: ≥98%

Peso molecular: 272.3g/mol

Ref: 54-BUP10436

α-Naphthoflavone

CAS: 604-59-1

Fórmula: C₁₉H₁₂O₂

Pureza: 95%~99%

Peso molecular: 272.303

Ref: BP-BP3065

α-Naphthoflavone

CAS: 604-59-1

alpha-Naphthoflavone (7,8-benzoflavone), a synthetic flavonoid, is a potent inhibitor of aromatase with an I50 value of 0.5 μM.

Fórmula: C₁₉H₁₂O₂

Pureza: 99.16% - 99.27%

Forma y color: Yellow

Peso molecular: 272.3

Ref: TM-T2O2744

α-Naphthoflavone

CAS: 604-59-1

α-Naphthoflavone

Fórmula: C₁₉H₁₂O₂

Pureza: 98%

Forma y color: yellow solid

Peso molecular: 272.30g/mol

Ref: 54-OR1158

α-Naphthylflavone

CAS: 604-59-1

Fórmula: C₁₉H₁₂O₂

Forma y color: Neat

Peso molecular: 272.30

Ref: TR-N372505

α-Naphthoflavone

CAS: 604-59-1

Alpha-naphthoflavone is a synthetic flavonoid, which is an aryl hydrocarbon receptor antagonist known for its interaction with cytochrome P450 enzymes. It is typically synthesized in laboratory settings and does not occur naturally. Alpha-naphthoflavone acts by competitively inhibiting the binding of ligands to the aryl hydrocarbon receptor (AhR) and modulating the activity of cytochrome P450 enzymes, particularly CYP1A1 and CYP1B1. This modulation is crucial in studying the metabolic pathways and the mechanism of enzyme induction or inhibition in xenobiotic metabolism.

Fórmula: C₁₉H₁₂O₂

Pureza: Min. 98.0 Area-%

Peso molecular: 272.31 g/mol

Ref: 3D-N-1500

7,8-Benzoflavone

CAS: 604-59-1

7,8-Benzoflavone is a synthetic flavonoid compound, which is derived from the structural modification of naturally occurring flavones. It possesses significant biochemical activity attributed to its ability to act as a potent inhibitor of certain cytochrome P450 enzymes, particularly CYP1A1 and CYP1B1. By inhibiting these enzymes, 7,8-Benzoflavone modulates the metabolism of various xenobiotics, impacting the bioactivation or detoxification of potential carcinogens.

Fórmula: C₁₉H₁₂O₂

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 272.3 g/mol

Ref: 3D-FB09432

a-Naphthoflavone extrapure AR, 98%

CAS: 604-59-1

Fórmula: C₁₉H₁₂O₂

Pureza: min. 98%

Forma y color: White to yellow, Crystalline powder, Clear

Peso molecular: 272.31

Ref: SR-57955

2-Phenyl-benzo[h]chromen-4-one

CAS: 604-59-1

Fórmula: C₁₉H₁₂O₂

Pureza: 98%

Forma y color: Solid, No data available.

Peso molecular: 272.303

Ref: 10-F058504