CAS 61-76-7

Clorhidrato de (-)-fenilefrina

Descripción:

Clorhidrato de (-)-fenilefrina es una amina simpaticomimética sintética que se utiliza principalmente como descongestionante y vasopresor. Se caracteriza por su capacidad para estimular selectivamente los receptores adrenérgicos alfa-1, lo que lleva a la vasoconstricción y al aumento de la presión arterial. Este compuesto se presenta típicamente como un polvo cristalino blanco a blanco amarillento, soluble en agua y alcohol, lo que facilita su uso en diversas formulaciones farmacéuticas. La fórmula molecular de Clorhidrato de (-)-fenilefrina es C9H13NO2·HCl, y tiene un peso molecular que refleja sus componentes estructurales, incluyendo un grupo fenólico y una cadena lateral de etilamina. Su estereoquímica es significativa, ya que el enantiómero (-) es la forma activa responsable de sus efectos terapéuticos. Comúnmente se encuentra en medicamentos de venta libre, se utiliza para aliviar la congestión nasal y como agente midriático en oftalmología. Sin embargo, es esencial monitorear su uso debido a posibles efectos secundarios, incluyendo hipertensión y bradicardia refleja, particularmente en poblaciones sensibles.

Fórmula: C₉H₁₃NO₂·ClH

InChI: InChI=1S/C9H13NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7;/h2-5,9-12H,6H2,1H3;1H/t9-;/m0./s1

Clave InChI: InChIKey=OCYSGIYOVXAGKQ-FVGYRXGTSA-N

SMILES: [C@@H](CNC)(O)C1=CC(O)=CC=C1.Cl

Sinónimos:

• (-)-α-Hydroxy-β-(methylamino)ethyl-α-(3-hydroxybenzene)hydrochloride
• (R)-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride
• (R)-3-(1-Hydroxy-2-(methylamino)ethyl)phenol hydrochloride
• (R)-3-Hydroxy-[α-(methylamino)methyl]benzene methanol hydrochloride
• (R)-3-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol hydrochloride
• (R)-Phenylephrine hydrochloride
• 3-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol hydrochloride
• Adrianol
• Ak-Dilate
• Ak-Nefrin
• Alcon Efrin
• Almefrin
• Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, hydrochloride (1:1), (αR)-
• Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, hydrochloride, (R)-
• Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, hydrochloride, (αR)-
• Benzyl alcohol, m-hydroxy-α-[(methylamino)methyl]-, hydrochloride, (-)-
• D-(-)-Phenylephrinehydrochloride
• Decadron
• Fenilefrina, Clorhidrato
• Irifrin
• Isophrin
• Isophrin hydrochloride
• Levophenylephrine hydrochloride
• Lexatol
• M-Sympatol
• Meta-Sympatol
• Meta-Synephrine hydrochloride
• Metaoxedrine chloride
• Metaoxedrine hydrochloride
• Mydfrin
• Neo-Synephrine hydrochloride
• Neo-Synesin 1
• Neophryn
• Neosinesine
• Nostril
• Oftalfrine
• Phenylephrine HCL
• Phenylephrine Hydrochloride
• Phenylephrine, chlorhydrate
• Phenylephrinhydrochlorid
• Prefrin
• Pyracort D
• R-(-)-m-Synephrine hydrochloride
• Sucraphen
• Synasal
• l-1-(m-Hydroxyphenyl)-2-methylaminoethanol hydrochloride
• l-m-Hydroxy-α-[(methylamino)methyl]benzyl alcohol hydrochloride
• l-α-Hydroxy-β-methylamino-3-hydroxy-1-ethylbenzene hydrochloride

(R)-Phenylephrine Hydrochloride

CAS: 61-76-7

Fórmula: C₉H₁₃NO₂·HCl

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystaline

Peso molecular: 203.67

Ref: 3B-P0398

Phenylephrine Hydrochloride

CAS: 61-76-7

Forma y color: Neat

Ref: 61-FOR0081.00

Phenylephrine hydrochloride

CAS: 61-76-7

Phenylephrine hydrochloride

Fórmula: C₉H₁₃NO₂HCl

Pureza: 100.0%

Forma y color: White

Peso molecular: 203.07131

Ref: 47-284

PHENYLEPHRINE HYDROCHLORIDE CRS

CAS: 61-76-7

PHENYLEPHRINE HYDROCHLORIDE CRS

Ref: 41-P1250000

PHENYLEPHRINE HYDROCHLORIDE FOR PEAK IDENTIFICATION CRS

CAS: 61-76-7

PHENYLEPHRINE HYDROCHLORIDE FOR PEAK IDENTIFICATION CRS

Fórmula: C₉H₁₄ClNO₂

Peso molecular: 203.666

Ref: 41-Y0000683

Phenylephrine Hydrochloride

CAS: 61-76-7

Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function

Fórmula: C₉H₁₃NO₂·ClH

Forma y color: White Off-White Crystalline Powder

Peso molecular: 203.07131

Ref: 45-1533002

Phenylephrine hydrochloride

CAS: 61-76-7

Phenylephrine hydrochloride (NCI-c55641) is a selective agonist of the α1-adrenergic receptor.

Fórmula: C₉H₁₄ClNO₂

Pureza: 99.51% - 99.97%

Forma y color: Physical Description Odorless White Microcrystalline Powder Bitter Taste Ph (1%

Peso molecular: 203.67

Ref: TM-T0453

(R)-3-(1-Hydroxy-2-(methylamino)ethyl)phenol hydrochloride

CAS: 61-76-7

Fórmula: C₉H₁₄ClNO₂

Pureza: 99%

Forma y color: Solid

Peso molecular: 203.6660

Ref: IN-DA00IAS9

Phenylephrine HCl

CAS: 61-76-7

Fórmula: C₉H₁₃NO₂·HCl

Forma y color: White To Off-White Solid

Peso molecular: 167.21 36.46

Ref: 4Z-P-2624

(R)-(-)-Phenylephrine hydrochloride, USP grade

CAS: 61-76-7

Fórmula: C₉H₁₃NO₂·HCl

Pureza: 97.5 - 102.0 %

Forma y color: White to off-white powder

Peso molecular: 203.67

Ref: 7W-GL0912

(R)-(-)-Phenylephrine hydrochloride

CAS: 61-76-7

Fórmula: C₉H₁₃NO₂·HCl

Pureza: (Titration) ≥ 99.0% (dried basis)

Forma y color: White to off-white powder

Peso molecular: 203.67

Ref: 7W-GL9617

Phenylephrine Hydrochloride

CAS: 61-76-7

Forma y color: Neat

Ref: 86-MM0081.00

Phenylephrine Hydrochloride

CAS: 61-76-7

Fórmula: C₉H₁₃NO₂HCl

Peso molecular: 167.21 : 36.46

Ref: ST-EA-CP-P12016

(R)-Phenylephrine Hydrochloride

CAS: 61-76-7

Stability Hygroscopic
Applications (R)-Phenylephrine Hydrochloride is an α-Adrenergic agonist. Mydriatic; decongestant.
References Warren, M.R., et al.: J. Pharmacol. Exp. Ther., 86, 284 (1946); Gaglia, C.A., et al.: Anal. Profiles Drug Subs., 3, 483 (1974);

Fórmula: C₉H₁₃NO₂·ClH

Forma y color: White To Off-White

Peso molecular: 203.67

Ref: TR-P320640

Phenylephrine hydrochloride

CAS: 61-76-7

(R)-Phenylephrine hydrochloride is a non selective alpha adrenergic agonist that can be used as a bronchodilator or vasopressor. Some research studies in rat liver microsomes has shown that (R)-phenylephrine can be converted to phenylephrine by alcohol dehydrogenase at a rate constant of around 1.8x103 M-1s-1 at 37°C. The biological effects of this compound are due to its ability to cause relaxation of smooth muscle and increase blood pressure by stimulating alpha-adrenergic receptors in the body. This drug is also used in chromatography for control analysis and detection of adulteration with other compounds, such as norepinephrine, with the help of benzalkonium chloride.In ophthalmology, phenylephrine hydrochloride formulations are used for the treatment of eye disorders such as myopia, hypermetropia and astigmatism. It increases the outflow of aqueous humour from the eye by acting on alpha receptors in the ciliary body, and seems to be effective in controlling symptoms of allergic rhinitis and chronic urticaria.

Fórmula: C₉H₁₄NO₂Cl

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 203.67 g/mol

Ref: 3D-FP26956

(R)-Phenylephrine HCl - Bio-X ™

CAS: 61-76-7

(R)-Phenylephrine is a non-selective α1-adrenoceptor agonist that can be used as a bronchodilator or vasopressor. The biological effects of this compound are due to its ability to cause relaxation of smooth muscle cells and increase blood pressure by stimulating alpha-adrenergic receptors in the body. Also, this drug is used to relieve nasal discomfort caused by colds and allergies and is used to relieve sinus congestion and pressure.

Fórmula: C₉H₁₃NO₂•HCl

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 203.67 g/mol

Ref: 3D-BP166231