CAS 6119-47-7

Clorhidrato de quinina dihidrato

Descripción:

Clorhidrato de quinina dihidrato es un compuesto químico derivado de la corteza del árbol de quina, conocido principalmente por su uso como agente antipalúdico. Es un polvo cristalino blanco a blanco sucio que es soluble en agua, lo que facilita su uso en diversas formulaciones farmacéuticas. El compuesto tiene un sabor amargo, característico de la quinina, y a menudo se utiliza en agua tónica y otras bebidas para dar sabor. Clorhidrato de quinina dihidrato tiene una fórmula molecular que incluye tanto quinina como ácido clorhídrico, junto con dos moléculas de agua, lo que contribuye a su clasificación como dihidrato. Además de sus propiedades antipalúdicas, se ha estudiado por sus posibles efectos analgésicos y antiinflamatorios. El compuesto actúa interfiriendo con la capacidad del parásito para metabolizar y utilizar hemoglobina, lo que lleva a su muerte. Las consideraciones de seguridad y dosificación son cruciales, ya que la ingesta excesiva puede provocar efectos secundarios como cinchonismo, caracterizado por síntomas como tinnitus y náuseas. En general, Clorhidrato de quinina dihidrato sigue siendo un compuesto importante tanto en contextos medicinales como culinarios.

Fórmula: C₂₀H₂₄N₂O₂·ClH·2H₂O

InChI: InChI=1S/C20H24N2O2.ClH.2H2O/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;;;/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;1H;2*1H2/t13-,14-,19-,20+;;;/m0.../s1

Clave InChI: InChIKey=MPQKYZPYCSTMEI-FLZPLBAKSA-N

SMILES: [C@@H](O)(C=1C2=C(C=CC(OC)=C2)N=CC1)[C@]3([N@@]4C[C@H](C=C)[C@](C3)(CC4)[H])[H].Cl.O

Sinónimos:

• (4beta,8alpha,9R)-6'-methoxycinchonan-9-ol hydrochloride dihydrate
• (9R)-6'-methoxycinchonan-1'-ium-9-ol chloride dihydrate
• (R)(6-Methoxy-4-quinolyl)(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanol hydrochloride
• Cinchonan-9-ol, 6′-methoxy-, hydrochloride, hydrate (1:1:2), (8α,9R)-
• Cinchonan-9-ol, 6′-methoxy-, monohydrochloride, dihydrate, (8α,9R)-
• Quinine Hydrochloride Dihydrate

Quinine Hydrochloride Dihydrate

CAS: 6119-47-7

Fórmula: C₂₀H₂₄N₂O₂·HCl·2H₂O

Pureza: >98.0%(T)

Forma y color: White to Almost white powder to crystal

Peso molecular: 396.91

Ref: 3B-Q0030

Quinine monohydrochloride dihydrate, 99% (total base), may contain up to 10% Dihydroquinine

CAS: 6119-47-7

It is used as pharmaceutical intermediate. Benzoylthiophenes are allosteric enhancers (AE) of agonist activity at the A1 adenosine receptor. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to t

Fórmula: C₂₀H₂₉ClN₂O₄

Pureza: 99%

Forma y color: Powder or crystalline powder or needles, White to pale cream

Peso molecular: 396.91

Ref: 02-H33474

Quinine.HCl.dihydrate, 1mg/ml in Ethanol (as free base)

CAS: 6119-47-7

Forma y color: Single Solution

Ref: LP-QUN-1135-HC-1LE

Quinine.HCl.dihydrate

CAS: 6119-47-7

Forma y color: Neat

Ref: LP-QUN-1135-HC-10

Quinine Hydrochloride Dihydrate

CAS: 6119-47-7

Quinine and its salts

Fórmula: C₂₀H₂₄N₂O₂·HCl·2H₂O

Forma y color: Colorless Needles

Peso molecular: 396.18159

Ref: 45-1596807

Quinine hydrochloride dihydrate

CAS: 6119-47-7

Fórmula: C₂₀H₂₄N₂O₂·HCl·2H₂O

Pureza: 99.0 - 101.0 %

Forma y color: White or almost white crystalline powder

Peso molecular: 396.91

Ref: 7W-GA8217

Quinine monohydrochloride dihydrate

CAS: 6119-47-7

Quinine monohydrochloride dihydrate

Fórmula: C₂₀H₂₄N₂O₂·ClH·2H₂O

Pureza: By hplc: 99.6% by area (Typical Value in Batch COA)

Forma y color: white crystalline powder

Peso molecular: 396.91g/mol

Ref: 54-BIQ1204

Quinine hydrochloride dihydrate

CAS: 6119-47-7

Quinine hydrochloride dihydrate

Pureza: ≥98%

Peso molecular: 396.91g/mol

Ref: 54-BUP19126

Quinine Hydrochloride Dihydrate

Producto controlado

CAS: 6119-47-7

Fórmula: C₂₀H₂₄N₂O₂·ClHH₂O

Forma y color: Neat

Peso molecular: 396.91

Ref: 86-MM1736.00

Quinine hydrochloride dihydrate

CAS: 6119-47-7

Fórmula: C₂₀H₂₉ClN₂O₄

Pureza: 95.0%

Forma y color: Solid

Peso molecular: 396.91

Ref: 10-F222360

Quinine hydrochloride dihydrate

CAS: 6119-47-7

Quinine hydrochloride dihydrate (Quinine HCl Dihydrate) is a white crystalline K+ channel blocker, used to treat malaria.

Fórmula: C₂₀H₂₄N₂O₂·HCl·2H₂O

Pureza: 99.91%

Forma y color: White To Light Yellow Crystal Powder

Peso molecular: 396.91

Ref: TM-T6631

Quinidine Hydrochloride Dihydrate

Producto controlado

CAS: 6119-47-7

Applications Quinidine Hydrochloride Dihydrate is a salt of Quinidine (Q685000), a dextrorotatory stereoisomer of Quinine. Antiarrhythmic (class IA). Antimalarial.
References Loutfy, M.A., et al.: Anal. Profiles Drug Subs., 12, 483 (1983), Mason, J. W., et al.: Ann. N. Y. Acad. Sci., 432, 162 (1984),

Fórmula: C₂₀H₂₄N₂O₂·ClH·2H₂O

Forma y color: White

Peso molecular: 396.91

Ref: TR-Q685045

Quinine hydrochloride dihydrate

CAS: 6119-47-7

Quinine hydrochloride dihydrate is a natural compound that has been used for centuries as a treatment for malaria. It is an effective anti-malarial agent and is also used to treat nocturnal leg cramps, although it has a low potency. Quinine hydrochloride dihydrate is active against the parasite Plasmodium falciparum in vitro. It binds to hemozoin, which is the pigment that the malaria parasites produce during digestion of hemoglobin from red blood cells. This binding inhibits the growth of the parasite and causes cell death by inhibiting protein synthesis. Quinine hydrochloride dihydrate has been shown to be genotoxic in vivo, but not in vitro. The genotoxic effects may be due to its ability to create reactive oxygen species (ROS) through photochemical reactions with light exposure and other chemical reactions, such as thermal expansion or matrix effects.

Fórmula: C₂₀H₂₄N₂O₂·HCl·2H₂O

Forma y color: Powder

Peso molecular: 396.91 g/mol

Ref: 3D-FQ43018