CAS 61318-91-0

nitrato de sulconazol

Descripción:

nitrato de sulconazol es un agente antifúngico utilizado principalmente en el tratamiento de infecciones dermatológicas, particularmente aquellas causadas por hongos y levaduras. Pertenece a la clase de derivados imidazólicos, que son conocidos por su capacidad para inhibir la síntesis de ergosterol, un componente crítico de las membranas celulares fúngicas. Este mecanismo interrumpe la integridad de la célula fúngica, llevando a la muerte celular. nitrato de sulconazol se formula típicamente como una crema o solución tópica, permitiendo un tratamiento localizado con una mínima absorción sistémica. El compuesto se caracteriza por su relativamente baja solubilidad en agua, lo que mejora su eficacia en aplicaciones tópicas. Además, exhibe un amplio espectro de actividad antifúngica contra varios patógenos, lo que lo convierte en una opción valiosa en entornos clínicos. Los perfiles de seguridad indican que generalmente es bien tolerado, con efectos secundarios que son raros y típicamente leves. Al igual que con cualquier medicamento, es esencial usar nitrato de sulconazol según lo indicado por un profesional de la salud para garantizar resultados terapéuticos óptimos y minimizar el riesgo de desarrollo de resistencia.

Fórmula: C₁₈H₁₆Cl₃N₃O₃S

InChI: InChI=1/C18H15Cl3N2S.HNO3/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21;2-1(3)4/h1-9,12,18H,10-11H2;(H,2,3,4)

Clave InChI: InChIKey=CRKGMGQUHDNAPB-UHFFFAOYSA-N

SMILES: C(CN1C=CN=C1)(SCC2=CC=C(Cl)C=C2)C3=C(Cl)C=C(Cl)C=C3.N(=O)(=O)O

Sinónimos:

• 1-[2-(4-Chlorobenzylthio)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate
• 1H-Imidazole, 1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-, (±)-, mononitrate
• 1H-Imidazole, 1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-, nitrate (1:1)
• Exelderm
• Rs 44872
• Rs 44872-00-10-3
• Sulcosyn
• Sulconazole nitrate
• Myk
• rs44872
• 1H-Imidazole, 1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-, nitrate (9CI)
• Sulconazole Nitrate (200 mg)
• 1-(2-(((4-chlorophenyl)methyl)thio)-2-(2,4-dichlorophenyl)ethyl)-1h-imidazol
• SULCONAZOLE NITRATE SALT
• ,mononitrate,(+-)-
• Sulconazole (mononitrate)
• Sulconazole nitrate,cas:61318-91-0
• 1H-IMidazole, 1-[2-[[(4-chlorophenyl)Methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-, nitrate
• 1-[2-(P-CHLOROBENZYLTHIO)-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE NITRATE
• Sulconazole nitrate salt,1-(2-[p-Chlorobenzylthio]-2-[2,4-dichlorophenyl]ethyl)-1H-imidazole
• Sulconazole nitrate USP/EP/BP
• 1H-Imidazole, 1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-, mononitrate (9CI)
• (+-)-1-(2,4-dichloro-beta-((4-chlorobenzyl)thio)phenethyl)imidazolenitrate
• 1-(2-[p-chlorobenzylthio]-2-[2,4-dichlorophenyl]ethyl)-1h-imidazole
• 1-[2-[(4-chlorophenyl)methylthio]-2-(2,4-dichlorophenyl)ethyl]imidazole

Sulconazole Nitrate

CAS: 61318-91-0

Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure nesoi

Fórmula: C₁₈H₁₅Cl₃N₂S

Forma y color: White Off-White Powder

Peso molecular: 396.00215

Ref: 45-1623681

SULCONAZOLENITRATE

CAS: 61318-91-0

Fórmula: C₁₈H₁₆Cl₃N₃O₃S

Pureza: 95%

Forma y color: Solid

Peso molecular: 460.7619

Ref: IN-DA00IAU9

Sulconazole mononitrate

CAS: 61318-91-0

Sulconazole mononitrate

Pureza: ≥98%

Peso molecular: 460.76g/mol

Ref: 54-BUP13871

Sulconazole Nitrate

CAS: 61318-91-0

Sulconazole Nitrate

Pureza: 99%

Peso molecular: 460.75g/mol

Ref: 54-OR1030138

Sulconazole nitrate salt

CAS: 61318-91-0

Fórmula: C₁₈H₁₅Cl₃N₂S·HNO₃

Pureza: ≥ 98.0%

Forma y color: White powder

Peso molecular: 460.76

Ref: 7W-GA8662

Sulconazole Nitrate

CAS: 61318-90-9, 61318-91-0

Fórmula: C₁₈H₁₅Cl₃N₂S·HNO₃

Pureza: >98.0%(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 460.75

Ref: 3B-U0112

Sulconazole Nitrate

Producto controlado

CAS: 61318-91-0

Fórmula: C₁₈H₁₅Cl₃N₂S·HNO₃

Forma y color: Neat

Peso molecular: 460.76

Ref: 86-MM3674.00

Sulconazole mononitrate

CAS: 61318-91-0

"Sulconazole mononitrate (Exelderm) is a synthetic antifungal imidazole that disrupts fungal cell membranes by inhibiting ergosterol synthesis."

Fórmula: C₁₈H₁₅Cl₃N₂S·HNO₃

Pureza: 99.75% - 99.92%

Forma y color: White Crystalline Powder

Peso molecular: 460.76

Ref: TM-T6686

Sulconazole Nitrate

Producto controlado

CAS: 61318-91-0

Applications Sulconazole Nitrate is an antifungal agent which prevents fungal growth by inhibiting sterol synthesis.
References Kinobe, R. et al.: J. Pharmacol. Exp. Ther., 319, 277 (2006); Ooishi, T. et al.: J. Japan. Soc. Hosp. Pharm., 31, 1449 (1995);

Fórmula: C₁₈H₁₅Cl₃N₂S·HNO₃

Forma y color: Neat

Peso molecular: 460.76

Ref: TR-S688940

Sulconazole Nitrate

CAS: 61318-91-0

Sulconazole Nitrate is a broad-spectrum antimicrobial agent that inhibits the growth of fungi by interfering with the synthesis of ergosterol, an important component of fungal cell membranes. Sulconazole Nitrate has been shown to possess in vitro antifungal activity against dimorphic fungi such as Candida albicans and Cryptococcus neoformans. It also has been shown to inhibit the growth of bacteria and other microbes through inhibition of fatty acid synthesis. This drug may be used as an adjuvant therapy for autoimmune diseases or infections caused by resistant strains of bacteria. Sulconazole Nitrate binds to fatty acids in the plasma membrane and prevents their incorporation into the phospholipid bilayer. The disruption of this process results in decreased cell membrane fluidity, which leads to a loss of structural integrity and cell permeability.

Fórmula: C₁₈H₁₅Cl₃N₂S·HNO₃

Pureza: Min. 95%

Peso molecular: 460.76 g/mol

Ref: 3D-FS76681