CAS 61477-96-1

Piperacilina

Descripción:

Piperacilina es un antibiótico penicilínico semisintético que se utiliza principalmente para tratar una variedad de infecciones bacterianas. Es eficaz contra un amplio espectro de bacterias grampositivas y gramnegativas, incluyendo Pseudomonas aeruginosa. Piperacilina actúa inhibiendo la síntesis de la pared celular bacteriana, lo que lleva a la lisis celular y a la muerte. El compuesto se administra típicamente por inyección, ya que no se absorbe bien cuando se toma por vía oral. Su estructura química incluye un anillo beta-lactámico, que es característico de las penicilinas, y una cadena lateral que mejora su actividad contra ciertas bacterias resistentes. Piperacilina a menudo se combina con un inhibidor de beta-lactamasa, como el tazobactam, para extender su eficacia contra organismos productores de beta-lactamasa. Los efectos secundarios comunes pueden incluir reacciones alérgicas, trastornos gastrointestinales y posibles impactos en la función renal. Debido a su actividad de amplio espectro, Piperacilina se utiliza con frecuencia en entornos hospitalarios para infecciones graves, particularmente en pacientes inmunocomprometidos.

Fórmula: C₂₃H₂₇N₅O₇S

InChI: InChI=1S/C23H27N5O7S/c1-4-26-10-11-27(19(32)18(26)31)22(35)25-13(12-8-6-5-7-9-12)16(29)24-14-17(30)28-15(21(33)34)23(2,3)36-20(14)28/h5-9,13-15,20H,4,10-11H2,1-3H3,(H,24,29)(H,25,35)(H,33,34)/t13-,14-,15+,20-/m1/s1

Clave InChI: InChIKey=IVBHGBMCVLDMKU-GXNBUGAJSA-N

SMILES: N(C([C@H](NC(=O)N1C(=O)C(=O)N(CC)CC1)C2=CC=CC=C2)=O)[C@H]3[C@@]4(N([C@@H](C(O)=O)C(C)(C)S4)C3=O)[H]

Sinónimos:

• (2S,5R,6R)-6-[[(2R)-2-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, [2S-[2α,5α,6β(S*)]]-
• Pipracil
• [2S-[2α,5α,6β(S*)]]-6-[[[[(4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-2-carbonsaure
• [2S-[2α,5α,6β(S*)]]-6-[[[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• acide [2S-[2α,5α,6β(S*)]]-6-[[[[(4-ethyl-2,3-dioxopiperazine-1-yl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylique
• acido [2S-[2α,5α,6β(S*)]]-6-[[[[(4-etil-2,3-dioxopiperazin-1-il)carbonil]amino]fenilacetil]amino]-3,3-dimetil-7-oxo-4-tia-1-azabiciclo[3.2.0]heptano-2-carboxilico
• Piperacillin

Piperacillin Sodium Salt

CAS: 59703-84-3, 61477-96-1

Fórmula: C₂₃H₂₆N₅NaO₇S

Pureza: >98.0%(N)

Forma y color: White to Almost white powder to crystal

Peso molecular: 539.54

Ref: 3B-P1774

Piperacillin, 95%

CAS: 61477-96-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₂₃H₂₆N₅NaO₇S

Pureza: 95%

Forma y color: White, Powder or crystals or crystalline powder

Peso molecular: 539.54

Ref: 02-J66143

Piperacillin

CAS: 61477-96-1

Forma y color: Neat

Ref: 61-FOR0295.00

(2S,5R,6R)-6-[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

CAS: 61477-96-1

Fórmula: C₂₃H₂₇N₅O₇S

Pureza: 98%

Forma y color: Solid

Peso molecular: 517.5548

Ref: IN-DA00IAVJ

Piperacillin

CAS: 61477-96-1

Pureza: ≥ 95.0%

Forma y color: White to off-white powder

Peso molecular: 517.56

Ref: 7W-GA9881

Piperacillin-d5 (N-ethyl-d5)

CAS: 61477-96-1

Fórmula: C₂₃H₂₂D₅N₅O₇S

Forma y color: White To Off-White Solid

Peso molecular: 522.59

Ref: 4Z-P-7410

Piperacillin

CAS: 61477-96-1

Fórmula: C₂₃H₂₇N₅O₇S

Forma y color: White To Off-White Solid

Peso molecular: 517.56

Ref: 4Z-P-7421

piperacillin

CAS: 61477-96-1

piperacillin

Pureza: ≥98%

Peso molecular: 517.55g/mol

Ref: 54-BUP16669

PharmaVetResiMix 6 Betalactams-v23 0.2-2.5 µg/mL in Water:Acetonitrile

CAS: 10206-21-0, 104557-24-6, 113-98-4, 118443-89-3, 132-98-9, 13412-64-1, 1385046-35-4, 23325-78-2, 24356-60-3, 27164-46-1, 50370-12-2, 56238-63-2, 61336-70-7, 61477-96-1, 62893-20-3, 63358-49-6, 68373-14-8, 7081-44-9, 7177-48-2, 7240-38-2, 80370-57-6, 89786-04-9, 985-16-0

Forma y color: Mixture

Ref: 04-A30000036WL

Piperacillin

Producto controlado

CAS: 61477-96-1

Fórmula: C₂₃H₂₇N₅O₇S

Forma y color: Neat

Peso molecular: 517.55

Ref: 86-MM0295.00

Piperacillin

Producto controlado

CAS: 61477-96-1

Fórmula: C₂₃H₂₇N₅O₇S

Forma y color: Neat

Peso molecular: 517.55

Ref: 04-C16218900

piperacillin

CAS: 61477-96-1

Piperacillin (Pipercillin) is a semisynthetic penicillin with wide spectrum of antimicrobial activity(particularly pseudomonas strains)

Fórmula: C₂₃H₂₇N₅O₇S

Pureza: 98.32% - 98.51%

Forma y color: Solid

Peso molecular: 517.55

Ref: TM-T8620

Piperacillin-d5 (phenyl-d5)

CAS: 61477-96-1

Fórmula: C₂₃H₂₂D₅N₅O₇S

Peso molecular: 522.59

Ref: 4Z-P-749

Piperacillin

Producto controlado

CAS: 61477-96-1

Applications Broad spectrum semi-synthetic antibiotic related to Penicillin. Antibacterial.
References Takai, A., et al.: Chemotherapy, 25, 816 (1977); Bodey, G.P., et al.: Antimicrob. Agents Chemother., 14, 78 (1978); Kuck, N.A., et al.: J. Antibiot., 31, 1175 (1978);

Fórmula: C₂₃H₂₇N₅O₇S

Forma y color: White

Peso molecular: 517.55

Ref: TR-P479950

Piperacillin-d5

Producto controlado

CAS: 61477-96-1

Fórmula: C₂₃₂H₅H₂₂N₅O₇S

Forma y color: Off-White

Peso molecular: 522.59

Ref: TR-P479952

Piperacillin

CAS: 61477-96-1

Piperacillin is a β-lactam antibiotic that inhibits the synthesis of bacterial cell walls by binding to penicillin-binding proteins. It is used for the treatment of serious infections caused by gram-negative organisms such as Aerogenes, Enterobacter, and Klebsiella. Piperacillin has a high MIC90 value against Staphylococcus and other gram-positive bacteria, but it is not active against β-lactamase producing strains of bacteria such as E. coli or Klebsiella pneumoniae. The MIC90 values are determined through an analytical method on different strains of bacteria and validated with a sample preparation before use in clinical trials.

Fórmula: C₂₃H₂₇N₅O₇S

Pureza: Min. 95 Area-%

Forma y color: White Powder

Peso molecular: 517.56 g/mol

Ref: 3D-FE27060

Piperacillin-d5

CAS: 61477-96-1

Piperacillin-d5 is a stable isotopically labeled antibiotic, which is synthesized chemically to incorporate deuterium atoms. It is derived from the β-lactam group of antibiotics, sharing properties with its non-labeled counterpart, piperacillin. The incorporation of five deuterium atoms allows researchers to use it as a tracer in various pharmacokinetic and metabolic studies without altering its biological activity.

Fórmula: C₂₃H₂₂D₅N₅O₇S

Pureza: Min. 95%

Peso molecular: 522.59 g/mol

Ref: 3D-AP184289