CAS 6190-39-2
:Mesilato de dihidroergotamina
Descripción:
Mesilato de dihidroergotamina es un derivado semisintético de los alcaloides del cornezuelo, utilizado principalmente en el tratamiento de migrañas y cefaleas en racimo. Actúa como un vasoconstrictor, dirigiéndose a los receptores de serotonina para aliviar los síntomas de dolor de cabeza. La sustancia se administra típicamente por vías intranasales o intravenosas, lo que permite un inicio rápido de acción. Mesilato de dihidroergotamina se caracteriza por su relativamente baja solubilidad en agua, lo que puede afectar su formulación y métodos de entrega. La forma de sal mesilato mejora su estabilidad y biodisponibilidad. Los efectos secundarios comunes pueden incluir náuseas, mareos y posibles efectos cardiovasculares debido a sus propiedades vasoconstrictivas. Está contraindicado en pacientes con ciertas condiciones cardiovasculares y debe usarse con precaución en aquellos con antecedentes de hipertensión. Como con todos los medicamentos, es esencial seguir las pautas de dosificación y monitorear las reacciones adversas. En general, Mesilato de dihidroergotamina es un agente terapéutico valioso en el manejo de ataques agudos de migraña, ofreciendo alivio a muchos pacientes cuando se usa adecuadamente.
Fórmula:C33H37N5O5·CH4O3S
InChI:InChI=1S/C33H37N5O5.CH4O3S/c1-32(35-29(39)21-15-23-22-10-6-11-24-28(22)20(17-34-24)16-25(23)36(2)18-21)31(41)38-26(14-19-8-4-3-5-9-19)30(40)37-13-7-12-27(37)33(38,42)43-32;1-5(2,3)4/h3-6,8-11,17,21,23,25-27,34,42H,7,12-16,18H2,1-2H3,(H,35,39);1H3,(H,2,3,4)/t21-,23-,25-,26+,27+,32-,33+;/m1./s1
Clave InChI:InChIKey=ADYPXRFPBQGGAH-UMYZUSPBSA-N
SMILES:O[C@@]12N([C@@H](CC3=CC=CC=C3)C(=O)N4[C@]1(CCC4)[H])C(=O)[C@@](NC(=O)[C@@H]5C[C@@]6(C=7C=8C(C[C@]6(N(C)C5)[H])=CNC8C=CC7)[H])(C)O2.S(C)(=O)(=O)O
Sinónimos:- (2'Ξ,5'Α,12'Ξ)-5'-Benzyl-12'-Hydroxy-2'-Methyl-3',6',18-Trioxo-9,10-Dihydroergotaman Methanesulfonate (Salt)
- (5'Alpha)-5'-Benzyl-12'-Hydroxy-2'-Methyl-3',6',18-Trioxo-9,10-Dihydroergotaman Methanesulfonate (Salt)
- (5'Alpha,10Alpha)-5'-Benzyl-12'-Hydroxy-2'-Methyl-3',6',18-Trioxo-9,10-Dihydroergotaman Methanesulfonate (1:1)
- 9,10-Dihydroergotamine mesylate
- Agit
- Angionorm
- Dergotamine
- Detms
- Dhe 45
- Diergo
- Dihydergot
- Dihydroergotamine Mesilate
- Dihydroergotamine Methanesulfonate
- Dihydroergotamine methanesulphonate
- Dihydroergotamine monomethanesulfonate
- Dihydroergotaminmesilat
- Dihytamine
- Dirgotarl
- Endophleban
- Ergomimet
- Ergont
- Ergotaman-3',6',18-trione, 9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'α,10α)-, methanesulfonate (1:1)
- Ergotaman-3',6',18-trione, 9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'α,10α)-, monomethanesulfonate (salt)
- Ergotaman-3′,6′,18-trione, 9,10-dihydro-12′-hydroxy-2′-methyl-5′-(phenylmethyl)-, (5′α,10α)-, methanesulfonate (1:1)
- Ergotaman-3′,6′,18-trione, 9,10-dihydro-12′-hydroxy-2′-methyl-5′-(phenylmethyl)-, (5′α,10α)-, monomethanesulfonate (salt)
- Ergotamine, 9,10-dihydro-, monomethanesulfonate (salt)
- Ergotonin
- Ikaran
- Mesilate De Dihydroergotamine
- Mesilato De Dihidroergotamina
- Migranal
- Morena
- Orstanorm
- Seglor
- Tonopres
- Verladyn
- (2'ξ,5'α,12'ξ)-5'-benzyl-12'-hydroxy-2'-methyl-3',6',18-trioxo-9,10-dihydroergotaman methanesulfonate (salt)
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Encontrado 13 productos.
Dihydroergotamine methanesulfonate
CAS:<p>Agonist at vascular serotonin receptors; partial agonist at alpha-adrenergic and dopamine D2 receptors This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aes</p>Fórmula:C34H41N5O8SForma y color:Powder or crystals or crystalline powder, White to pale yellow to pale redPeso molecular:679.79DIHYDROERGOTAMINE FOR PEAK IDENTIFICATION CRS
CAS:DIHYDROERGOTAMINE FOR PEAK IDENTIFICATION CRSFórmula:C34H41N5O8SPeso molecular:679.783DIHYDROERGOTAMINE MESILATE CRS
CAS:DIHYDROERGOTAMINE MESILATE CRSFórmula:C34H41N5O8SForma y color:Crystalline Powder. White. Colourless Crystals. Powder.Peso molecular:679.783Dihydroergotamine Mesylate
CAS:Alkaloids of rye ergot and their derivatives; salts thereof, nesoiFórmula:C33H37N5O5·CH4O3SForma y color:White Off-White PowderPeso molecular:679.26758Dihydroergotamine methanesulfonate salt
CAS:Fórmula:C33H37N5O5·CH4O3SForma y color:White to pale-yellow or pale-red powder or crystalsPeso molecular:679.78Dihydroergotamine Mesylate
CAS:Fórmula:C33H37N5O5·CH4O3SPureza:>97.0%(HPLC)Forma y color:White to Light yellow to Light red powder to crystalPeso molecular:679.79Dihydroergotamine Mesylate
CAS:Producto controlado<p>Applications α-Androgenic blocker with selective venoconstrictor properties. Also binds to serotonin 5HT1-receptors. Antimigraine.<br>References de Marees, et al.: Eur. J. Clin. Pharmacol., 30, 685 (1986), McCarthy, B.G., et al.: Headache, 29, 420 (1989), Ziegler, D., et al.: Neurology, 44, 447 (1994),<br></p>Fórmula:C33H37N5O5·CH4O3SForma y color:White To Off-WhitePeso molecular:679.78Dihydro ergotamine mesylate
CAS:Producto controlado<p>Dihydroergotamine mesylate is a medication that is used in the treatment of migraines. It belongs to the group of drugs called ergot alkaloids and has been shown to have high values in cerebral metabolism. Dihydroergotamine mesylate has also been shown to have an effect on dopamine levels in human serum, which may be due to its ability to inhibit neuronal death. Dihydroergotamine mesylate is administered intravenously, orally or intramuscularly for the treatment of acute migraine attacks. The drug can also be given rectally for the prevention of chronic migraine episodes. This drug may cause side effects such as nausea, vomiting and dizziness.</p>Fórmula:C34H41N5O8SPureza:Min. 95%Forma y color:PowderPeso molecular:679.78 g/molDihydroergotamine mesylate
CAS:Producto controladoFórmula:C33H37N5O5·CH4O3SForma y color:NeatPeso molecular:679.78
