CAS 62340-29-8

Oximodulina

Descripción:

Oximodulina es una hormona péptida que se produce principalmente en las células L intestinales en respuesta a la ingesta de alimentos. Es una molécula de 37 aminoácidos que comparte similitudes estructurales con el glucagón y el GLP-1 (péptido similar al glucagón-1), desempeñando un papel significativo en la regulación del apetito y el equilibrio energético. Se ha demostrado que Oximodulina suprime el apetito y aumenta el gasto energético, convirtiéndolo en un tema de interés en la investigación sobre la obesidad y los trastornos metabólicos. Su mecanismo de acción implica la unión al receptor de GLP-1 y al receptor de glucagón, lo que influye en la secreción de insulina y el metabolismo de la glucosa. Además, Oximodulina puede tener efectos sobre la motilidad gástrica y la secreción de ácido gástrico. Debido a sus efectos fisiológicos, tiene aplicaciones terapéuticas potenciales en el manejo del peso y el tratamiento de la diabetes. El número CAS 62340-29-8 identifica de manera única este compuesto en bases de datos químicas, facilitando la investigación y el desarrollo en farmacología y bioquímica.

Fórmula: Unspecified

Sinónimos:

• Enteroglucagonoid
• Gut glucagon
• Glucagon, entero-
• Oxyntomodulin
• Enteroglucagon

Oxyntomodulin

CAS: 62340-29-8

GLP-1 analog modulates appetite, boosts metabolism, and curbs gastric acid. Increases cAMP, mildly stimulates glucagon receptor.

Fórmula: C₁₉₂H₂₉₅N₅₉O₆₀S

Pureza: 98%

Forma y color: Solid

Peso molecular: 4421.86

Ref: TM-TP1976

Oxyntomodulin, Glucagon-37 (Porcine)

CAS: 62340-29-8

Oxyntomodulin, a peptide hormone made up of 37 amino acids, is produced and released from gut endocrine L-cells. It has the ability to regulate gastric acids secretion in the gastric oxyntic glands. Oxyntomodulin, Glucagon-37 (Porcine) product is avaiable in the Trifluoroacetate salt form and can be used as an inhibitor of gastric acid secretion and pancreatic enzyme secretion. It has also been shown to reduce food intake and increase energy expenditure in humans. Central injection of oxyntomodulin reduces food intake and weight gain in rodents, suggesting that oxyntomodulin signals food ingestion to hypothalamic appetite-regulating circuits.

Fórmula: C₁₉₂H₂₉₅N₅₉O₆₀S

Pureza: Min. 95%

Peso molecular: 4,421.92 g/mol

Ref: 3D-PGL-3827-PI

Oxyntomodulin (porcine, bovine)

CAS: 62340-29-8

Oxyntomodulin is a peptide hormone that is used as a pharmacological treatment for diabetes. Oxyntomodulin is an analogue of glucagon, which belongs to the family of glucagon-like peptide-1 (GLP-1) agonists. Oxyntomodulin has been shown to improve glucose tolerance and increase insulin secretion in humans and animals. This drug has also been shown to decrease appetite and improve weight loss in overweight patients with type 2 diabetes. The physiological effects of oxyntomodulin are mediated by GLP-1 receptors on multiple organs, including the pancreas, liver, gut, adipose tissue, brain, heart, and kidneys. Oxyntomodulin also inhibits the activity of dipeptidyl peptidase IV (DPP-IV), which may have therapeutic benefits for type 2 diabetes by slowing gastric emptying and increasing satiety. The administration of oxyntomodulin leads to increased mitochondrial membrane potential in

Fórmula: C₁₉₂H₂₉₅N₅₉O₆₀S

Pureza: Min. 95%

Peso molecular: 4,421.86 g/mol

Ref: 3D-MCA34029