CAS 63166-73-4

Filantosido

Descripción:

Filantosido, con el número CAS 63166-73-4, es un compuesto glucósido derivado principalmente de plantas del género Phyllanthus. Se caracteriza por su estructura, que típicamente incluye un moiety de azúcar unido a un aglicona fenólica. Este compuesto es conocido por sus potenciales propiedades farmacológicas, incluyendo efectos antioxidantes, antiinflamatorios y hepatoprotectores. Filantosido ha sido estudiado por su papel en la medicina tradicional, particularmente en el tratamiento de enfermedades relacionadas con el hígado. Su solubilidad y estabilidad pueden variar dependiendo del disolvente y las condiciones ambientales, lo que puede influir en su biodisponibilidad y eficacia. Además, la investigación sobre su mecanismo de acción y aplicaciones terapéuticas está en curso, destacando su importancia en la química de productos naturales y la farmacognosia. Al igual que muchos compuestos derivados de plantas, los procesos de extracción y purificación pueden afectar el rendimiento y la pureza de Filantosido, lo que hace esencial emplear metodologías apropiadas para su estudio y aplicación.

Fórmula: C₄₀H₅₂O₁₇

InChI: InChI=1S/C40H52O17/c1-19-17-48-40(16-28(19)54-29(43)14-11-24-9-7-6-8-10-24)39(18-49-39)26-13-12-25(15-27(26)57-40)36(47)56-38-35(34(53-23(5)42)31(45)21(3)51-38)55-37-32(46)33(52-22(4)41)30(44)20(2)50-37/h6-11,14,19-21,25-28,30-35,37-38,44-46H,12-13,15-18H2,1-5H3/b14-11+/t19-,20-,21-,25+,26+,27-,28+,30-,31-,32-,33+,34+,35-,37+,38+,39+,40+/m1/s1

Clave InChI: InChIKey=VOTNXJVGRXZYOA-VFRDRLLTSA-N

SMILES: O(C(/C=C/C1=CC=CC=C1)=O)[C@H]2C[C@]3([C@@]4([C@@]5([C@](O3)(C[C@@H](C(O[C@H]6[C@H](O[C@H]7[C@H](O)[C@@H](OC(C)=O)[C@H](O)[C@@H](C)O7)[C@@H](OC(C)=O)[C@H](O)[C@@H](C)O6)=O)CC5)[H])[H])CO4)OC[C@H]2C

Sinónimos:

• Dispiro[oxirane-2,3′(2′H)-benzofuran-2′,2′′-[2H]pyran], β-<span class="text-smallcaps">D</span>-glucopyranose deriv.
• NSC 328426
• Phyllanthoside
• beta-D-glucopyranose, 2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-1-O-[[(2S,2'R,3a'R,4''S,5''R,6'R,7a'S)-decahydro-5''-methyl-4''-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]oxy]dispiro[oxirane-2,3'(2'H)-benzofuran-2',2''-[2H]pyran]-6'-yl]carbonyl]-6-deoxy-, 3-acetate
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranose, 2-O-(3-O-acetyl-6-deoxy-β-<smallcap>D</span>-glucopyranosyl)-6-deoxy-, 3-acetate 1-[(2R,2′S,3′aS,4′′S,5′′R,6′S,7′aR)-decahydro-5′′-methyl-4′′-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]oxy]dispiro[oxirane-2,3′(2′H)-benzofuran-2′,2′′-[2H]pyran]-6′-carboxylate]
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranose, 2-O-(3-O-acetyl-6-deoxy-β-<smallcap>D</span>-glucopyranosyl)-6-deoxy-, 3-acetate 1-[(2R,2′S,3′aS,4′′S,5′′R,6′S,7′aR)-decahydro-5′′-methyl-4′′-[[(2E)-1-oxo-3-phenyl-2-propenyl]oxy]dispiro[oxirane-2,3′(2′H)-benzofuran-2′,2′′-[2H]pyran]-6′-carboxylate]
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranose, 2-O-(3-O-acetyl-6-deoxy-β-<smallcap>D</span>-glucopyranosyl)-6-deoxy-, 3-acetate 1-[decahydro-5′′-methyl-4′′-[(1-oxo-3-phenyl-2-propenyl)oxy]dispiro[oxirane-2,3′(2′H)-benzofuran-2′,2′′-[2H]pyran]-6′-carboxylate], [2′S-[2′α[4′′R*(E),5′′S*],3′β,3′aα,6′α,7′aα]]-
• β-D-Glucopyranose, 2-O-(3-O-acetyl-6-deoxy-β-D-glucopyranosyl)-6-deoxy-, 3-acetate 1-[decahydro-5′′-methyl-4′′-[(1-oxo-3-phenyl-2-propenyl)oxy]dispiro[oxirane-2,3′(2′H)-benzofuran-2′,2′′-[2H]pyran]-6′-carboxylate], [2′S-[2′α[4′′R*(E),5′′S*],3′β,3′aα,6′α,7′aα]]-
• 3-O-Acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2S,2'R,3a'R,4''S,5''R,6'R,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose
• Dispiro[oxirane-2,3′(2′H)-benzofuran-2′,2′′-[2H]pyran], β-D-glucopyranose deriv.
• β-D-Glucopyranose, 2-O-(3-O-acetyl-6-deoxy-β-D-glucopyranosyl)-6-deoxy-, 3-acetate 1-[(2R,2′S,3′aS,4′′S,5′′R,6′S,7′aR)-decahydro-5′′-methyl-4′′-[[(2E)-1-oxo-3-phenyl-2-propen-1-yl]oxy]dispiro[oxirane-2,3′(2′H)-benzofuran-2′,2′′-[2H]pyran]-6′-carboxylate]

Phyllanthoside - Phyllanthus acuminatus

CAS: 63166-73-4

Phyllanthoside is a natural compound derived from the plant Phyllanthus acuminatus, a species known for its diverse phytochemical composition. The source of this compound is a flowering plant within the Phyllanthaceae family, which has been traditionally used in various herbal medicine practices. Phyllanthoside functions primarily by disrupting cancer cell proliferation through mechanisms related to DNA intercalation and inhibition of topoisomerase enzymes. This impedes the replication process of rapidly dividing cells, demonstrating potential applications in anticancer therapies. Studies have focused on its cytotoxic effects against various cancer cell lines, highlighting its promise in the development of new chemotherapeutic agents. Further research into its efficacy and safety profile remains essential, as does the exploration of its full pharmacological potential.

Fórmula: C₄₀H₅₂O₁₇

Pureza: Min. 90 Area-%

Forma y color: Clear Liquid

Peso molecular: 804.83 g/mol

Ref: 3D-XP170495

Phyllanthoside

CAS: 63166-73-4

Fórmula: C₄₀H₅₂O₁₇

Peso molecular: 804.84

Ref: 4Z-P-380001