CAS 63234-80-0

3-(2-cloroetil)-6,7,8,9-tetrahidro-2-metil-4H-pirido[1,2-a]pirimidin-4-ona

Descripción:

3-(2-cloroetil)-6,7,8,9-tetrahidro-2-metil-4H-pirido[1,2-a]pirimidin-4-ona, con el número CAS 63234-80-0, es un compuesto químico que pertenece a la clase de los pirido-pirimidinas. Esta sustancia presenta una estructura bicíclica compleja que incluye un anillo de piridina y un anillo de pirimidina, lo que contribuye a sus propiedades químicas únicas. La presencia de un grupo cloroetilo aumenta su reactividad, haciéndolo potencialmente útil en varias reacciones químicas, incluidas las sustituciones nucleofílicas. La configuración de tetrahidro indica que el compuesto está saturado en ciertas posiciones, lo que puede influir en su actividad biológica y solubilidad. Además, el grupo metilo unido al anillo de piridina puede afectar las propiedades estéricas y electrónicas del compuesto. Este compuesto puede exhibir actividades farmacológicas, aunque se necesitarían datos biológicos específicos para determinar sus posibles aplicaciones en química medicinal. En general, sus características estructurales sugieren que podría ser de interés en el desarrollo de nuevos agentes terapéuticos o como un bloque de construcción en la síntesis orgánica.

Fórmula: C₁₁H₁₅ClN₂O

InChI: InChI=1/C11H15ClN2O/c1-8-9(5-6-12)11(15)14-7-3-2-4-10(14)13-8/h2-7H2,1H3

Clave InChI: InChIKey=CMWCQQUYLPYOMY-UHFFFAOYSA-N

SMILES: O=C1N2C(=NC(C)=C1CCCl)CCCC2

Sinónimos:

• 3-(2-Chloroethyl)-6,7,8,9-Tetrahydro-2-Methyl-4H-Pyrido-(1,2-A) Pyrimidin-4-One
• 4H-Pyrido[1,2-a]pyrimidin-4-one, 3-(2-chloroethyl)-6,7,8,9-tetrahydro-2-methyl-
• 3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
• 3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-A]pyrimidin-4-one
• 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2
• 3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]-pyrididine-4-one (intermediate of Risperidone)
• 3-(2-CHLOROETHYL)-6,7,8,9-TETRAHYDRO-2-METHYL-4H-PYRIDO[1,2-A]-PYRIMIDIN-4-ONE(RISPERIDONEINTERMEDIATE)
• -a]pyrimidin-4-one
• 3-2(2-chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-alpha]pyrimnidin-4-one
• 3-(2-CHLOROETHYL)-6,7,8,9-TETRAHYDRO-2-METHYL-4H-PYRIDINO[1,2-A]PYRIMIDINE-4-ONE
• 8-(CHLOROETHYL)-9-METHYL-6,10-DIAZABICYCLO[4.4.0]DECA-8,10-DIEN-7-ONE
• 3-(2-CHLOROETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO[1, 2-A]-PYRIMIDIN-4-ONE ( RISPERIDONE INTERMEDIATE ).
• 3-2(2-CHLOROETHYL)-6,7,8,9-TETRAHYDRO-2-METHYL-4H-PYRIDO[1,2-A]PYRIMDIN-4-ONE
• 3-(2-CHLOROETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO[1,2-A]-PYRIDIDINE-4-ONE
• 3-(2-CHLORO-ETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-PYRIDO[1,2-A]PYRIMIDIN-4-ONE
• 3-(2-Chloroethyl)-2-Methyl-6,7,8,9-tetrahydro-4H-pyrimidine-4-one
• 3-(2-CHLOROETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO[1,2-ALPHA]PYRIMIDIN-4-ONE
• 3-(2-CHLOROETHYL)-6,7,8,9-TETRAHYDRO-2-METHYL-4H-PYRLDO[1,2-A]PYRIMDIN-4-ONE
• 3-(2-CHLOROETHYL)-6,7,8,9-TETRAHYDRO-2-METHYL-4H-PYRIDO(1,2A)PYRIMIDINE-4-ONE

3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

CAS: 63234-80-0

Fórmula: C₁₁H₁₅ClN₂O

Pureza: >98.0%(GC)(T)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 226.70

Ref: 3B-C2433

Risperidone Pyridopyrimidinone Analog (3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one)

CAS: 63234-80-0

Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoi

Fórmula: C₁₁H₁₅ClN₂O

Forma y color: Off-White Solid

Peso molecular: 226.08729

Ref: 45-1A11420

Risperidone EP Impurity L

CAS: 63234-80-0

Fórmula: C₁₁H₁₅ClN₂O

Forma y color: White To Off-White Solid

Peso molecular: 226.70

Ref: 4Z-R-0633

3-(2-Chloroethyl)-6,7,8,9-Tetrahydro-2-Methyl-4H-Pyrido[1,2-a]Pyrimidin-4-One

CAS: 63234-80-0

3-(2-Chloroethyl)-6,7,8,9-Tetrahydro-2-Methyl-4H-Pyrido[1,2-a]Pyrimidin-4-One

Pureza: 98%

Peso molecular: 226.70g/mol

Ref: 54-OR1010638

Risperidone EP Impurity L

CAS: 63234-80-0

Fórmula: C₁₁H₁₅ClN₂O

Peso molecular: 263.16

Ref: ST-EA-CP-R15012

3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one

Producto controlado

CAS: 63234-80-0

Impurity Risperidone EP Impurity L
Applications 3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one (Risperidone EP Impurity L) is an intermediate in the synthesis of Risperidone (R525000), which is a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.
References Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988), Gelders, Y.G., et al.: Pharmacopsychiatry, 23, 206 (1990), Green, B.: Curr. Med. Res. Opin., 16, 57 (2000)

Fórmula: C₁₁H₁₅ClN₂O

Forma y color: Neat

Peso molecular: 226.70

Ref: TR-C366155

3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one

CAS: 63234-80-0

3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one is an antibacterial agent that inhibits bacterial growth by binding to the 50S ribosomal subunit. It is a white crystalline powder that is soluble in methanol and acetonitrile. 3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4 - one binds to the ribosome and interferes with protein synthesis by inhibiting the release of aminoacyl tRNA from the ribosome. The drug has been shown to have antibacterial activity against Gram positive and Gram negative bacteria. 3-(2) Chloroethyl)-2-methyl 6,7

Fórmula: C₁₁H₁₅ClN₂O

Pureza: Min. 95 Area-%

Forma y color: Powder

Peso molecular: 226.7 g/mol

Ref: 3D-FC20229

3-(2-CHLORO-ETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-PYRIDO[1,2-A]PYRIMIDIN-4-ONE

CAS: 63234-80-0

Fórmula: C₁₁H₁₅ClN₂O

Pureza: 97%

Forma y color: Solid

Peso molecular: 226.7

Ref: 10-F300981