CAS 63610-08-2

Indobufeno

Descripción:

Indobufeno es un medicamento antiinflamatorio no esteroideo (AINE) utilizado principalmente por sus propiedades analgésicas y antiinflamatorias. Se caracteriza por su capacidad para inhibir las enzimas ciclooxigenasas, que juegan un papel crucial en la síntesis de prostaglandinas, reduciendo así el dolor y la inflamación. Indobufeno se utiliza a menudo en el tratamiento de diversas condiciones, incluyendo la artritis y otros trastornos inflamatorios. El compuesto se administra típicamente por vía oral y es conocido por su inicio de acción relativamente rápido. Su estructura química incluye un grupo fenilo y un moiety de ácido butírico, contribuyendo a sus efectos farmacológicos. Indobufeno también se destaca por sus posibles efectos secundarios, que pueden incluir trastornos gastrointestinales y riesgos cardiovasculares, similares a otros AINE. Al igual que con cualquier medicamento, es esencial usar Indobufeno bajo supervisión médica para gestionar la dosis y monitorear reacciones adversas. En general, Indobufeno representa una opción valiosa en el manejo del dolor y la inflamación, con un perfil específico que lo distingue de otros AINE.

Fórmula: C₁₈H₁₇NO₃

InChI: InChI=1S/C18H17NO3/c1-2-15(18(21)22)12-7-9-14(10-8-12)19-11-13-5-3-4-6-16(13)17(19)20/h3-10,15H,2,11H2,1H3,(H,21,22)

Clave InChI: InChIKey=AYDXAULLCROVIT-UHFFFAOYSA-N

SMILES: O=C1N(CC=2C1=CC=CC2)C3=CC=C(C(C(O)=O)CC)C=C3

Sinónimos:

• (2R)-2-[4-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)phenyl]butanoic acid
• 1-Oxo-2-[p-[(α-ethyl)carboxymethyl]phenyl]isoindoline
• 2-(4-(1-Oxoisoindolin-2-yl)phenyl)butanoic acid
• 2-[4-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)phenyl]butanoic acid
• 2-[p-(1-Oxo-2-isoindolinyl)phenyl]butyric acid
• 4-(1,3-Dihydro-1-oxo-(2H)-isoindol-2-yl)-alpha-ethylbenzeneacetic acid
• 4-(1,3-Dihydro-1-oxo-2H-isoindol-2-yl)-α-ethylbenzeneacetic acid
• Benzeneacetic acid, 4-(1,3-dihydro-1-oxo-2H-isoindol-2-yl)-α-ethyl-
• Ibustrin
• K 2930
• K 3920

Indobufen

CAS: 63610-08-2

Fórmula: C₁₈H₁₇NO₃

Pureza: >98.0%(GC)(T)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 295.34

Ref: 3B-I1178

(2S)-2-[4-(3-oxo-1H-isoindol-2-yl)phenyl]butanoic acid

CAS: 63610-08-2

Fórmula: C₁₈H₁₇NO₃

Pureza: 97%

Forma y color: Solid

Peso molecular: 295.3325

Ref: IN-DA01CBW2

Indobufen

CAS: 63610-08-2

Indobufen (Ibustrin) is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor.

Fórmula: C₁₈H₁₇NO₃

Pureza: 99.27% - 99.44%

Forma y color: Solid

Peso molecular: 295.33

Ref: TM-T15577

Indobufen

CAS: 63610-08-2

Indobufen

Pureza: ≥98%

Peso molecular: 295.33g/mol

Ref: 54-BUP13709

Indobufen

CAS: 63610-08-2

Fórmula: C₁₈H₁₇NO₃

Forma y color: White To Off-White Solid

Peso molecular: 295.34

Ref: 4Z-I-511

2-(4-(1-Oxoisoindolin-2-Yl)Phenyl)Butanoic Acid

CAS: 63610-08-2

2-(4-(1-Oxoisoindolin-2-Yl)Phenyl)Butanoic Acid

Pureza: 99%

Peso molecular: 295.33g/mol

Ref: 54-OR1029819

Indobufen-d5

CAS: 63610-08-2

Fórmula: C₁₈H₁₂D₅NO₃

Forma y color: White To Off-White Solid

Peso molecular: 300.37

Ref: 4Z-I-5110

Indobufen

CAS: 63610-08-2

Fórmula: C₁₈H₁₇NO₃

Peso molecular: 295.33

Ref: 7W-GP5189

Indobufen

CAS: 63610-08-2

Indobufen is a drug that belongs to the group of non-steroidal anti-inflammatory drugs. It has been shown to be effective in treating infectious diseases, including malaria and bacterial infections. Indobufen has been shown to inhibit the production of prostaglandin E2 (PGE2) in an experimental model at low doses. This inhibition leads to reduced levels of PGE2 receptor activity and decreased enzyme activities such as cyclooxygenase and lipoxygenase, which are involved in inflammation. This drug also inhibits platelet aggregation and increases bleeding time. The effects of indobufen on human pharmacokinetics have been studied using human serum and platelet samples from healthy volunteers. Indobufen is rapidly absorbed, with a half-life of 1 hour, and it is metabolized by cytochrome P450 (CYP450). Indobufen has also been shown to increase cardiac contractility without affecting heart rate or blood pressure levels.

Fórmula: C₁₈H₁₇NO₃

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 295.33 g/mol

Ref: 3D-FI37690

Indobufen

Producto controlado

CAS: 63610-08-2

Applications Indobufen is a platelet aggregation inhibitor. Indobufen is the anticoagulant drug and platelet aggregation inhibitor, which has anti-inflammatory analgesic effect. Indobufen is used as an antithrombotic.
References Diener, H., et al.: J. Neurol. Sci., 143, 1 (1996), Brainin, M., et al.: Eur. J. Neurol., 7, 5 (2005), Culebras, A., et al.: Neurology, 62, 1073 (2004), Lopez, A., et al.: Lancet, 367, 1747 (2006),

Fórmula: C₁₈H₁₇NO₃

Forma y color: Neat

Peso molecular: 295.33

Ref: TR-I576500

Indobufen

CAS: 63610-08-2

Fórmula: C₁₈H₁₇NO₃

Peso molecular: 295.34

Ref: ST-EA-CP-I87000