CAS 64-75-5

(-)-Clorhidrato de tetraciclina

Descripción:

(-)-Clorhidrato de tetraciclina es un antibiótico de amplio espectro que pertenece a la clase de las tetraciclinas, utilizado principalmente para tratar diversas infecciones bacterianas. Se caracteriza por su compleja estructura policíclica, que incluye cuatro anillos fusionados, lo que contribuye a su capacidad para inhibir la síntesis de proteínas en las bacterias al unirse a la subunidad ribosomal 30S. Este compuesto se presenta típicamente como una sal de clorhidrato, lo que mejora su solubilidad en agua. (-)-Clorhidrato de tetraciclina exhibe un color amarillo a naranja y es sensible a la luz, lo que puede llevar a su degradación. Es efectivo contra una amplia gama de bacterias grampositivas y gramnegativas, así como algunos protozoos. La sustancia también es conocida por sus propiedades antiinflamatorias y a veces se utiliza en el tratamiento del acné y otras afecciones cutáneas. Sin embargo, su uso puede provocar efectos secundarios, incluidos trastornos gastrointestinales y fotosensibilidad. Debido a su potencial para causar decoloración dental en niños, su uso generalmente se evita en mujeres embarazadas y niños pequeños. El almacenamiento adecuado alejado de la luz y la humedad es esencial para mantener su estabilidad y eficacia.

Fórmula: C₂₂H₂₄N₂O₈·ClH

InChI: InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1

Clave InChI: InChIKey=XMEVHPAGJVLHIG-FMZCEJRJSA-N

SMILES: O[C@@]12[C@@](C[C@]3(C(=C1O)C(=O)C=4C([C@@]3(C)O)=CC=CC4O)[H])([C@H](N(C)C)C(O)=C(C(N)=O)C2=O)[H].Cl

Sinónimos:

• (2E,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
• (2Z,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4S,4aS,5aS,6S,12aS)-
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aS,5aS,6S,12aS)-
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4S-(4α,4aα,5aα,6β,12aα)]-
• 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthalenecarboxamide hydrochloride
• 4-(Dimethylamino)-3,6,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide Hydrochloride (1:1)
• Achro
• Achromycin hydrochloride
• Ala-Tet
• Ambracyn
• Bristaciclina
• Bristacycline
• Cancycline-250
• Cefracycline
• Criseociclina
• Cyclopar
• Diocyclin
• Dumocyclin
• Helvecyclin
• Heromycin
• Hostacyclin
• Hostacycline
• Imex
• Laudin
• Medamycin
• Neocycline B
• Paltet
• Panmycin hydrochloride
• Partrex
• Polycycline hydrochloride
• Polyotic ointment
• Purocyclina
• Quadracyclin
• Remicyclin
• Riocyclin
• Ro-Cycline
• Robitet
• Sanclomycine
• Steclin
• Subamycin
• Sumycin
• Supramycin
• Sustamycin
• Talcin
• Tefilin
• Tet-Cy
• TetraSURE
• Tetrabakat
• Tetrabid
• Tetrablet
• Tetrabon
• Tetracaps
• Tetrachel
• Tetraciclina, Clorhidrato
• Tetracompren
• Tetracycline chlorohydrate
• Tetracycline hcl
• Tetracycline, chlorhydrate
• Tetracyclinhydrochlorid
• Tetracyklin
• Tetracyn
• Tetrakap
• Tetralution
• Tetramavan
• Tetrosol
• Topicycline
• Totomycin
• Triphacyclin
• Unicin
• Vetquamycin 324

Tetracycline Hydrochloride

CAS: 64-75-5

Fórmula: C₂₂H₂₄N₂O₈HCl

Peso molecular: 444.4 : 36.46

Ref: ST-EA-CP-T200003

Tetracycline hydrochloride

CAS: 64-75-5

Antibiotic of tetracycline class; protein synthesis inhibitor

Fórmula: C₂₂H₂₅ClN₂O₈

Forma y color: Yellow Powder

Peso molecular: 480.9 g/mol

Ref: 3D-AT28073

Tetracycline hydrochloride - USP

CAS: 64-75-5

Tetracycline hydrochloride - USP is a broad-spectrum antibiotic, which is a synthetic derivative of chlortetracycline produced from the bacterium *Streptomyces aureofaciens*. It functions by inhibiting protein synthesis in bacteria, specifically binding to the 30S ribosomal subunit. This action prevents the attachment of aminoacyl-tRNA to the mRNA-ribosome complex, thereby halting bacterial growth and replication.

Fórmula: C₂₂H₂₅ClN₂O₈

Forma y color: Yellow Powder

Peso molecular: 480.9 g/mol

Ref: 3D-AT168330

Tetracycline Hydrochloride (TC) for tissue culture, 95%

CAS: 64-75-5

Fórmula: C₂₂H₂₄N₂O₈·HCl

Pureza: min. 95%

Forma y color: Yellow, Crystalline powder

Peso molecular: 480.90

Ref: SR-82175

Tetracycline Hydrochloride (TC), 95%

CAS: 64-75-5

Fórmula: C₂₂H₂₄N₂O₈·HCl

Pureza: min. 95%

Forma y color: Yellow, Crystalline powder

Peso molecular: 480.90

Ref: SR-38614

Tetracycline hydrochloride

CAS: 64-75-5

Pureza: 98%

Peso molecular: 479.89

Ref: 10-F951532

Tetracycline hydrochloride, Antibiotic for Culture Media Use Only

CAS: 64-75-5

Tetracycline hydrochloride is a broad-spectrum antibiotic and is an electron transfer agent. It has been shown to be effective against bacterial infections in humans and has been used in cultures for the prevention of bacterial contamination. As an electron transfer agent, it is used in electron microscopy to study the surface of biological cells. Tetracycline hydrochloride enters bacterial cells by diffusion and interacts with the cytoplasmic membrane, where it induces a redox reaction that leads to cell death. The efficacy of tetracycline hydrochloride in treating candida albicans (yeast) was studied using in-vitro activity and showed that carboxymethyl chitosan nanoparticles were able to enhance the treatment efficiency.

Fórmula: C₂₂H₂₅ClN₂O₈

Pureza: Min. 88.0 Area-%

Peso molecular: 480.90 g/mol

Ref: 3D-T-1961

Tetracycline hydrochloride (10mg/ml)

CAS: 64-75-5

Tetracycline hydrochloride (10mg/ml)

Forma y color: Solution

Peso molecular: 494.92g/mol

Ref: 54-BIG1033