CAS 641-77-0

4-pregneno-11-B-17-A-diol-3-20-diona

Descripción:

4-Pregnene-11β,17α-diol-3,20-diona, comúnmente conocida como 17α-hidroxiprogesterona, es una hormona esteroide que juega un papel crucial en la regulación de varios procesos fisiológicos. Es un derivado de la progesterona y se caracteriza por sus características estructurales específicas, incluyendo un esqueleto de pregnene con grupos hidroxilo en las posiciones 11 y 17 y una cetona en las posiciones 3 y 20. Este compuesto está principalmente involucrado en la biosíntesis de otras hormonas esteroides y es significativo en la salud reproductiva, particularmente en el embarazo. Se sintetiza en las glándulas suprarrenales y en las gónadas y es conocido por su papel en el mantenimiento del embarazo y la regulación de los ciclos menstruales. En entornos clínicos, la 17α-hidroxiprogesterona se utiliza terapéuticamente para prevenir el parto prematuro en embarazos de alto riesgo. La sustancia se administra típicamente en varias formas, incluyendo inyecciones o formulaciones orales. Sus efectos farmacológicos se median a través de interacciones con receptores específicos de hormonas esteroides, influyendo en la expresión génica y la actividad celular. Al igual que muchas hormonas esteroides, sus niveles en el cuerpo están estrictamente regulados y pueden verse afectados por diversas condiciones fisiológicas y patológicas.

Fórmula: C₂₁H₃₀O₄

InChI: InChI=1/C21H30O4/c1-12(22)21(25)9-7-16-15-5-4-13-10-14(23)6-8-19(13,2)18(15)17(24)11-20(16,21)3/h10,15-18,24-25H,4-9,11H2,1-3H3

Clave InChI: InChIKey=LCZBQMKVFQNSJR-UJPCIWJBSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(CC3)=CC(=O)CC4)([C@@H](O)C1)[H])[H])(CC[C@@]2(C(C)=O)O)[H]

Sinónimos:

• (11Alpha)-11,17-Dihydroxypregn-4-Ene-3,20-Dione
• (11Beta)-11,17-Dihydroxypregn-4-Ene-3,20-Dione
• (11β)-11,17-Dihydroxypregn-4-ene-3,20-dione
• 11,17-Dihydroxypregn-4-Ene-3,20-Dione
• 11-Beta,17-Alpha-Dihydroxypregn-4-Ene-3,20-Dione
• 11β,17α-Dihydroxypregn-4-ene-3,20-dione
• 11β,17α-Dihydroxyprogesterone
• 21-Dehydrohydrocortisone
• 21-Deoxycortisol
• 21-Deoxyhydrocortisone
• 21-Desoxycortisol
• Pregn-4-ene-11β,17α-diol-3,20-dione
• Pregn-4-ene-3,20-dione, 11,17-dihydroxy-, (11β)-
• Pregn-4-ene-3,20-dione, 11β,17-dihydroxy-
• Progesterone, 11β,17-dihydroxy-
• 21 DEOXYCORTISOL 21-DESOXYCORTISOL
• 21-Deoxycortisol solution
• 4-Pregnene-11β,17α-diol-3,20-dione
• 4-Pregnen-11,17a-diol-3,20-dione-d8
• Hydrocortisone EP Impurity L Q: What is the CAS Number of
• Hydrocortisone EP Impurity L (Oxenol)
• HYDROCORTISONE IMPURITY L (OXENOL)
• (8S,9S,10R,13S,14S,17R)-17-acetyl-11,17-dihydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
• Desoxycortisol (solution)
• 11β,17α-Dihydroxy-4-pregnene-3,20-dione, 11β,17α-Dihydroxyprogesterone, 21-Desoxycortisol, 4-Pregnene-11β,17α-diol-3,20-dione
• Hydrocortisone EP Impurity L Q: What are the applications of
• 4-pregnene-11-B-17-A-diol-3-20-dione
• Hydrocortisone impurity L (EP)
• Hydrocortisone EP Impurity L
• 11β,17-Dihydroxypogesterone
• Hydrocortisone EP IMP L
• C05497
• Desoxycortisol
• 11BETA,17ALPHA-DIHYDROXY-PROGESTERONE
• 11β,17α-Dihydroxy-4-pregnene-3,20-dione
• 11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE
• Hydrocortisone EP Impurity LQ: What is
• Hydrocortisone EP Impurity L (Hydrocortisone Acetate EP Impurity B)
• Hydrocortisone Acetate EP Impurity B (Hydrocortisone EP Impurity L)
• (8S,9S,10R,11S,13S,14S,17R)-17-Acetyl-11,17-dihydroxy-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one
• Hydrocortisone Impurity L
• 4-PREGNEN-11BETA,17ALPHA-DIOL-3,20-DIONE
• Hydrocortisone EP Impurity L Q: What is the storage condition of
• 4-PREGNENE-11BETA,17ALPHA-DIOL-3,20-DIONE
• Hydrocortisone Impurity 12（Hydrocortisone EP Impurity L）
• 11β,17-Dihydroxypregn-4-ene-3,20-dione
• Hydrocortisone Acetate EP Impurity B

21-Deoxycortisol (11β,17-Dihydroxypregn-4-ene-3,20-dione)

CAS: 641-77-0

Ketone-alcohols and ketone-aldehydes, nesoi

Fórmula: C₂₁H₃₀O₄

Forma y color: White Powder

Peso molecular: 346.21441

Ref: 45-1A10610

(8S,9S,10R,11S,13S,14S,17R)-17-Acetyl-11,17-dihydroxy-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one

CAS: 641-77-0

Fórmula: C₂₁H₃₀O₄

Pureza: 98%

Forma y color: Solid

Peso molecular: 346.4605

Ref: IN-DA00EBWG

Hydrocortisone EP Impurity L (Hydrocortisone Acetate EP Impurity B, Oxenol)

CAS: 641-77-0

Fórmula: C₂₁H₃₀O₄

Peso molecular: 346.47

Ref: 4Z-H-103022

21-Deoxycortisol

CAS: 641-77-0

21-Deoxycortisol

Pureza: 98%

Ref: 54-OR1039799

11β,17-Dihydroxypregn-4-ene-3,20-dione (Oxenol)

CAS: 641-77-0

Forma y color: Neat

Ref: 86-MM0185.28

21-Deoxy Cortisol

Producto controlado

CAS: 641-77-0

Impurity Hydrocortisone EP Impurity L
Applications 21-Deoxy Cortisol (Hydrocortisone EP Impurity L) is a metabolite of Fluticasone propionate (F599500).
References Li, S., et al.: Science, 303, 540 (2004), Fliri, A., et al.: J. Med. Chem., 48, 6918 (2005), Ekins, S., et al.: J. Pharmacol. Toxicol. Methods, 53, 38 (2006),

Fórmula: C₂₁H₃₀O₄

Forma y color: Neat

Peso molecular: 346.46

Ref: TR-D232605

21-Deoxycortisol

Producto controlado

CAS: 641-77-0

21-Deoxycortisol is a synthetic steroid that is used as a diagnostic agent in vitro to differentiate between deficiency type I (21-hydroxylase) and deficiency type II (11β-hydroxylase) of the adrenal gland. 21-Deoxycortisol has structural similarity to cortisol, but it does not bind to receptors in the body. The absence of this binding makes it useful for diagnosis. The measurement of serum cortisol levels can be used to diagnose these deficiencies as well, but this test is less specific than the 21-deoxycortisol assay. In addition, there are significant interactions with other drugs that may affect the accuracy of these measurements. This drug is also used as a model system for studying physiological processes and interactions with drugs.

Fórmula: C₂₁H₃₀O₄

Pureza: Min. 95%

Forma y color: Off-White Powder

Peso molecular: 346.46 g/mol

Ref: 3D-FD21046

Hydrocortisone EP Impurity L

CAS: 641-77-0

Fórmula: C₂₁H₃₀O₄

Peso molecular: 346.5

Ref: ST-EA-CP-H9012