CAS 644-62-2

Ácido meclofenámico

Descripción:

Ácido meclofenámico es un fármaco antiinflamatorio no esteroideo (AINE) utilizado principalmente por sus propiedades analgésicas y antiinflamatorias. Pertenece a la clase de AINEs fenamatos y se caracteriza por su capacidad para inhibir las enzimas ciclooxigenasas, que desempeñan un papel crucial en la síntesis de prostaglandinas involucradas en la inflamación y el dolor. La fórmula química de Ácido meclofenámico es C15H14ClN y presenta un anillo de clorobenceno, un grupo fenilo y un grupo funcional ácido carboxílico, que contribuyen a su actividad farmacológica. Se administra típicamente en forma oral y está indicado para el tratamiento de condiciones como la artritis y la dismenorrea. Ácido meclofenámico es conocido por sus posibles efectos secundarios, que pueden incluir trastornos gastrointestinales, riesgos cardiovasculares y deterioro renal, lo que requiere un monitoreo cuidadoso durante su uso. Además, es importante considerar las contraindicaciones y las interacciones con otros medicamentos. En general, Ácido meclofenámico es un potente agente antiinflamatorio con una estructura química específica que subyace a sus efectos terapéuticos.

Fórmula: C₁₄H₁₁Cl₂NO₂

InChI: InChI=1/C14H11Cl2NO2.Na/c1-8-6-7-10(15)13(12(8)16)17-11-5-3-2-4-9(11)14(18)19;/h2-7,17H,1H3,(H,18,19);/q;+1/p-1

Clave InChI: InChIKey=SBDNJUWAMKYJOX-UHFFFAOYSA-N

SMILES: N(C1=C(Cl)C(C)=CC=C1Cl)C2=C(C(O)=O)C=CC=C2

Sinónimos:

• 2-[(2,6-Dichloro-3-methylphenyl)amino]benzoic acid
• Acide Meclofenamique
• Acido Meclofenamico
• Anthranilic acid, N-(2,6-dichloro-m-tolyl)-
• Arquel
• Inf 4668
• Meclofenamic Acid
• Meclofenamicsaure
• Meclophenamic acid
• N-(2,6-Dichloro-3-methylphenyl)anthranilic acid
• N-(2,6-Dichloro-m-tolyl)anthranilic acid
• N-(3-Methyl-2,6-dichlorophenyl)anthranilic acid
• Nsc 95309
• Meclomen
• sodium 2-[(2,6-dichloro-3-methylphenyl)amino]benzoate
• Meclofen
• Benzoic acid, 2-[(2,6-dichloro-3-methylphenyl)amino]-
• 2-(2,6-dichloro-3-methyl-anilino)benzoic acid
• Meclorfenamic
• 2-(2,6-dichloro-3-methylanilino)benzoic acid

Meclofenamic Acid

CAS: 644-62-2

Forma y color: Neat

Ref: 61-FOR3124.00

2-((2,6-Dichloro-3-methylphenyl)amino)benzoic acid

CAS: 644-62-2

2-((2,6-Dichloro-3-methylphenyl)amino)benzoic acid

Pureza: 95%

Peso molecular: 296.15g/mol

Ref: 54-OR1073263

Meclofenamic acid

Producto controlado

CAS: 644-62-2

Fórmula: C₁₄H₁₁Cl₂NO₂

Forma y color: Neat

Peso molecular: 296.15

Ref: 04-C14804500

Meclofenamic Acid

Producto controlado

CAS: 644-62-2

Fórmula: C₁₄H₁₁Cl₂NO₂

Forma y color: Neat

Peso molecular: 296.15

Ref: 86-MM3124.00

Meclofenamic Acid

Producto controlado

CAS: 644-62-2

Applications Meclofenamic Acid is anti-inflammatory. It is used as an antipyretic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Juby, et al.: J. Med. Chem., 11, 111 (1968), Winder, et al.: J. Pharmacol. Exp. Ther., 148, 422 (1965), Rees, M.C.P., et al.: Lancet, 2, 541 (1988),

Fórmula: C₁₄H₁₁Cl₂NO₂

Forma y color: Neat

Peso molecular: 296.15

Ref: TR-M202750

Meclofenamic acid

CAS: 644-62-2

Meclofenamic acid is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits the activity of cyclooxygenase and lipoxygenase. It is used for the treatment of mild to moderate pain, dysmenorrhea, and menstrual cramps. Meclofenamic acid binds to polymerase chain reaction (PCR) substrate-binding site, inhibiting DNA synthesis in rat hippocampal neurons. This drug has also been shown to suppress disease activity in animals with experimental arthritis. Meclofenamic acid can be administered orally or intravenously without altering its effect on disease activity or blood sampling results. The drug is rapidly metabolized by hydroxylation and conjugation with glucuronic acid, followed by excretion in urine or feces. Meclofenamic acid significantly cytotoxic to human polymorphonuclear leukocytes at high concentrations, which may be due to its ability to modify RNA synthesis and protein synthesis.

Fórmula: C₁₄H₁₁Cl₂NO₂

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 296.15 g/mol

Ref: 3D-FM25028

Meclofenamic acid

CAS: 644-62-2

Meclofenamic acid: non-selective gap-junction blocker, FTO inhibitor, anti-inflammatory.

Fórmula: C₁₄H₁₁Cl₂NO₂

Pureza: 99.98%

Forma y color: Solid

Peso molecular: 296.15

Ref: TM-T11990