CAS 64987-85-5

Succinimidil 4-(N-maleimidometil) ciclohexanocarboxilato

Descripción:

Succinimidil 4-(N-maleimidometil) ciclohexanocarboxilato, con el número CAS 64987-85-5, es un compuesto químico comúnmente utilizado en aplicaciones de bioconjugación y etiquetado de proteínas. Presenta un grupo funcional de éster succinimidilo, conocido por su capacidad para reaccionar con grupos amino en proteínas, facilitando la formación de enlaces amida estables. La presencia de un grupo maleimida permite la conjugación selectiva a grupos tiol, lo que lo hace particularmente útil en la creación de bioconjugados dirigidos. Este compuesto se caracteriza típicamente por su estado sólido a temperatura ambiente y es soluble en disolventes orgánicos como el dimetilsulfóxido (DMSO) y el dimetilformamida (DMF). Su reactividad y especificidad lo hacen valioso en varios campos, incluida la bioquímica y la biología molecular, para aplicaciones como la entrega de medicamentos, ensayos diagnósticos y el desarrollo de agentes terapéuticos. Las condiciones adecuadas de manejo y almacenamiento son esenciales para mantener su estabilidad y reactividad, ya que puede ser sensible a la humedad y la luz.

Fórmula: C₁₆H₁₈N₂O₆

InChI: InChI=1S/C16H18N2O6/c19-12-5-6-13(20)17(12)9-10-1-3-11(4-2-10)16(23)24-18-14(21)7-8-15(18)22/h5-6,10-11H,1-4,7-9H2

Clave InChI: InChIKey=JJAHTWIKCUJRDK-UHFFFAOYSA-N

SMILES: C(N1C(=O)C=CC1=O)C2CCC(C(ON3C(=O)CCC3=O)=O)CC2

Sinónimos:

• (2,5-Dioxopyrrolidin-1-yl) 4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexane-1-carboxylate
• 1-[(4-{[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl}cyclohexyl)methyl]-1H-pyrrole-2,5-dione
• 1H-Pyrrole-2,5-dione, 1-[[4-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl]methyl]-
• 2,5-Dioxopyrrolidin-1-yl 4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexancarboxylate
• 2,5-Dioxopyrrolidin-1-yl 4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxylate
• 4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid N-hydroxysuccinimide ester
• 4-(N-Maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester
• Cyclohexanecarboxylic acid, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-, 2,5-dioxo-1-pyrrolidinyl ester
• N-Hydroxysuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate
• N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate
• N-Succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate
• N-Succinimidyl 4-(maleimidomethyl)cyclohexanecarboxylate
• N-Succinimidyl4-(N-maleimidomethyl)cyclohexane-1-carboxylate
• NSC 344483
• Smcc
• Succinimidyl 4-(N-maleimidomethyl)cyclohexanecarboxylate
• Succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate
• Succinimidyl 4-[maleimidomethyl]cyclohexan-1-carboxylate

N-Succinimidyl 4-(Maleimidomethyl)cyclohexane-1-carboxylate

CAS: 64987-85-5

Fórmula: C₁₆H₁₈N₂O₆

Pureza: 95%

Forma y color: Solid

Peso molecular: 334.3239

Ref: IN-DA0038KF

SMCC

CAS: 64987-85-5

SMCC

Pureza: ≥98%

Peso molecular: 334.32g/mol

Ref: 54-BUP16020

N-Succinimidyl 4-(N-Maleimidomethyl)cyclohexanecarboxylate

CAS: 64987-85-5

Fórmula: C₁₆H₁₈N₂O₆

Pureza: >98.0%(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 334.33

Ref: 3B-S0853

Succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate

CAS: 64987-85-5

Succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate

Fórmula: C₁₆H₁₈N₂O₆

Pureza: By hplc: 99.8% (Typical Value in Batch COA)

Forma y color: white solid

Peso molecular: 334.32g/mol

Ref: 54-BICL206

SMCC

CAS: 64987-85-5

SMCC (N-Succinimidyl 4-(N-maleimidomethyl)cycl) is a heterobifunctional protein crosslinker.

Fórmula: C₁₆H₁₈N₂O₆

Pureza: 98.96% - 99.53%

Forma y color: White Crystalline Solid

Peso molecular: 334.32

Ref: TM-T9116

N-Succinimidyl 4-(Maleimidomethyl)cyclohexane-1-carboxylate

Producto controlado

CAS: 64987-85-5

Applications A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. It conjugates anti-digoxin F(ab’)2 fragments to ß-galactosidase. Conjugates hIgG to alkaline phosphatase.Spacer Arm: 11.6 Angstroms
References Maham, D.G., et al.: Anal. Biochem., 162, 163 (1987), Yoshitake, S., et al.: Eur. J. Biochem., 101, 395 (1979), Freytag, J.W., et al.: Clin. Chem., 30(9), 1494 (1984), Mahan, D.E., et al.: Anal. Biochem., 162, 163 (1987), Peeters, J.M., et al.: J. Immunol. Meth., 120, 133 (1989),

Fórmula: C₁₆H₁₈N₂O₆

Forma y color: Neat

Peso molecular: 334.32

Ref: TR-S690400

N-Succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate

CAS: 64987-85-5

N-Succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate is a versatile compound with a wide range of applications. It is commonly used in research settings as a cross-linking agent and can be utilized in the synthesis of various compounds such as ribavirin, farnesene, temozolomide, gliclazide, and more.

Fórmula: C₁₆H₁₈N₂O₆

Pureza: Min. 98 Area-%

Forma y color: White Powder

Peso molecular: 334.32 g/mol

Ref: 3D-FS27894

2,5-Dioxopyrrolidin-1-yl 4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxylate

CAS: 64987-85-5

Fórmula: C₁₆H₁₈N₂O₆

Pureza: 95%

Forma y color: Solid, White powder

Peso molecular: 334.328

Ref: 10-F214622

Succinimidyl-4-(N- (N-maleimidomethyl) cyclohexane-1-carboxylate (SMCC), 98%

CAS: 64987-85-5

Fórmula: C₁₆H₁₈N₂O₆

Pureza: min. 98%

Forma y color: White, Crystalline powder

Peso molecular: 334.32

Ref: SR-24088