CAS 65-28-1

Mesilato de fentolamina

Descripción:

Mesilato de fentolamina es un antagonista alfa-adrenérgico no selectivo que se utiliza principalmente en entornos clínicos para manejar condiciones como la hipertensión y contrarrestar los efectos de ciertos tipos de anestesia. Es una forma salina de fentolamina, que mejora su solubilidad y biodisponibilidad. El compuesto aparece como un polvo cristalino blanco a blanco sucio y es soluble en agua, lo que lo hace adecuado para la administración intravenosa. Su mecanismo de acción implica bloquear los receptores alfa-adrenérgicos, lo que lleva a la vasodilatación y a una disminución de la presión arterial. Mesilato de fentolamina también se utiliza en el tratamiento del feocromocitoma, un tumor de la glándula adrenal que secreta catecolaminas en exceso. Los efectos secundarios pueden incluir taquicardia, mareos y trastornos gastrointestinales. Debido a sus propiedades farmacológicas, es esencial monitorear a los pacientes de cerca al administrar este medicamento, particularmente en aquellos con problemas cardiovasculares. En general, Mesilato de fentolamina es un agente terapéutico valioso en escenarios médicos específicos, destacando la importancia de la modulación de los receptores adrenérgicos en la farmacoterapia.

Fórmula: C₁₇H₁₉N₃O·CH₄O₃S

InChI: InChI=1S/C17H19N3O.CH4O3S/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15;1-5(2,3)4/h2-8,11,21H,9-10,12H2,1H3,(H,18,19);1H3,(H,2,3,4)

Clave InChI: InChIKey=OGIYDFVHFQEFKQ-UHFFFAOYSA-N

SMILES: S(C)(=O)(=O)O.N(CC=1NCCN1)(C2=CC(O)=CC=C2)C3=CC=C(C)C=C3

Sinónimos:

• 3-[(4,5-dihydro-1H-imidazol-2-ylmethyl)(4-methylphenyl)amino]phenol methanesulfonate (1:1)
• M-(N-(2-Imidazolin-2-Ylmethyl)-P-Toluidino)-
• Phenol, 3-[[(4,5-dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino]-, methanesulfonate (1:1)
• Phenol, 3-[[(4,5-dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino]-, monomethanesulfonate (salt)
• Phenol, m-[N-(2-imidazolin-2-ylmethyl)-p-toluidino]-, monomethanesulfonate (salt)
• Phenomonomethanesulfonate
• Phentolamine Mesilate
• Phentolamine Methanesulfonate
• Phentolamine methanesulfonate salt
• Phentolamine methanesulphonate
• Phentolaminemethanesulphonate
• Regitin methanesulphonate
• Regitine mesylate
• Regitine methanesulfonate
• Rogitine
• Vasomax
• m-[N-(2-Imidazolin-2-ylmethyl)-p-toluidino]phenol methanesulfonate

Phentolamine Mesylate

CAS: 65-28-1

Fórmula: C₁₇H₁₉N₃O·CH₄O₃S

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Light yellow to Light orange powder to crystal

Peso molecular: 377.46

Ref: 3B-P1985

PHENTOLAMINE MESILATE CRS

CAS: 65-28-1

PHENTOLAMINE MESILATE CRS

Fórmula: C₁₈H₂₃N₃O₄S

Forma y color: Crystalline Powder. White. Powder.

Peso molecular: 377.4579

Ref: 41-Y0001127

PHENTOLAMINE FOR SYSTEM SUITABILITY CRS

CAS: 65-28-1

PHENTOLAMINE FOR SYSTEM SUITABILITY CRS

Fórmula: C₁₈H₂₃N₃O₄S

Peso molecular: 377.4579

Ref: 41-Y0001251

Phentolamine mesilate

CAS: 65-28-1

Phentolamine mesilate

Fórmula: C₁₈H₂₃N₃O₄S

Pureza: 99.0%

Forma y color: Off-White

Peso molecular: 377.14093

Ref: 47-520

Phentolamine impurity standard

CAS: 65-28-1

Phentolamine impurity standard

Forma y color: Off-White

Ref: 47-1099

Phentolamine Mesylate

CAS: 65-28-1

Compounds containing an unfused imidazole ring, whether or not hydrogenated, in the structure, nesoi

Fórmula: C₁₇H₁₉N₃O·CH₄O₃S

Forma y color: White Off-White Crystalline Powder

Peso molecular: 377.14093

Ref: 45-1530004

Phentolamine mesylate

CAS: 65-28-1

Phentolamine mesylate: nonselective alpha-blocker for hypertension, pheochromocytoma, Raynaud's, frostbite, impotence, and vascular issues.

Fórmula: C₁₇H₁₉N₃O·CH₄O₃S

Pureza: 99.87% - >99.99%

Forma y color: By The Metabolic Processes Of Bacillus Subtilis And Licheniformis

Peso molecular: 377.46

Ref: TM-T1275

Phentolamine mesylate

CAS: 65-28-1

Fórmula: C₁₇H₁₉N₃O·CH₃SO₃H

Pureza: ≥ 98.0%

Forma y color: White to off-white crystalline powder

Peso molecular: 377.46

Ref: 7W-GP7407

Phentolamine mesylate

CAS: 65-28-1

Phentolamine mesylate

Pureza: ≥98%

Peso molecular: 377.46g/mol

Ref: 54-BUP17117

Phentolamine Mesylate

CAS: 65-28-1

Phentolamine Mesylate

Pureza: 98%

Peso molecular: 377.46g/mol

Ref: 54-OR1029394

Phentolamine Mesylate

CAS: 65-28-1

Fórmula: C₁₇H₁₉N₃O·CH₄O₃S

Forma y color: White To Off-White Solid

Peso molecular: 281.36 96.11

Ref: 4Z-P-189001

Phentolamine Mesilate

CAS: 65-28-1

Fórmula: C₁₇H₁₉N₃O·CH₄O₃S

Forma y color: Neat

Peso molecular: 377.46

Ref: 86-MM1310.00

Phentolamine Methanesulfonate Salt

Producto controlado

CAS: 65-28-1

Stability Aq. Solutions Cannot be Stored
Applications Phentolamine Methanesulfonate Salt is an adrenergic blocking agent. An antihypertensive. Used for the treatment of pheochromocytoma.
References Meier, R., et al.: Proc. Soc. Exp. Biol. Med., 71, 70 (1949); Spergel, G., et al.: J. Am. Med. Assoc., 211, 266 (1970); Gould, L. and Reddy, C.V.R.: Am. Heart J., 92, 397 (1976);

Fórmula: C₁₇H₁₉N₃O·CH₄O₃S

Forma y color: Off-White

Peso molecular: 377.46

Ref: TR-P302560

Phentolamine methanesulfonate

CAS: 65-28-1

Phentolamine is a synthetic mesylate that is used as an antihypertensive agent, and for the treatment of Raynaud's syndrome and pheochromocytoma. Phentolamine is also used to prevent frostbite and to treat various types of shock. Phentolamine blocks alpha-2-adrenergic receptors, thereby decreasing sympathetic nerve impulses to the heart, blood vessels, kidneys, and other organs. This drug also acts as a histamine antagonist by blocking H1-receptors on vascular smooth muscle cells. Phentolamine has been shown to have no significant effects on 5-hydroxytryptamine (5HT) release in vitro or in vivo.

Fórmula: C₁₈H₂₃N₃O₄S

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 377.46 g/mol

Ref: 3D-FP26896

Phentolamine Mesilate

CAS: 65-28-1

Forma y color: Neat

Ref: 61-FOR1310.00