CAS 653-63-4

dAMP

Descripción:

La sustancia química conocida como dAMP, o monofosfato de desoxiadenosina, es un nucleótido que desempeña un papel crucial en la bioquímica de los ácidos nucleicos. Es un bloque de construcción del ADN, que consiste en un azúcar desoxirribosa, un grupo fosfato y una base de adenina. El número CAS 653-63-4 identifica de manera única este compuesto en bases de datos químicas. dAMP está involucrado en varios procesos biológicos, incluida la síntesis y reparación del ADN, ya que sirve como precursor para la síntesis de trifosfato de desoxiadenosina (dATP), que es esencial para la replicación del ADN. En términos de sus propiedades físicas, dAMP es típicamente un polvo blanco a blanco sucio que es soluble en agua, reflejando su naturaleza polar debido al grupo fosfato. Su estabilidad puede verse influenciada por factores como el pH y la temperatura, y es sensible a la hidrólisis. En entornos de laboratorio, dAMP se utiliza en aplicaciones de biología molecular, incluyendo PCR y otras técnicas de manipulación del ADN, destacando su importancia en la investigación genética y la biotecnología.

Fórmula: C₁₀H₁₄N₅O₆P

InChI: InChI=1S/C10H14N5O6P/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(21-7)2-20-22(17,18)19/h3-7,16H,1-2H2,(H2,11,12,13)(H2,17,18,19)/t5-,6+,7+/m0/s1

Clave InChI: InChIKey=KHWCHTKSEGGWEX-RRKCRQDMSA-N

SMILES: NC1=C2C(N(C=N2)[C@@H]3O[C@H](COP(=O)(O)O)[C@@H](O)C3)=NC=N1

Sinónimos:

• 2'-Deoxy-5'-O-phosphonatoadenosine
• 2'-Deoxyadenosine 5'-monophosphate
• 2'-deoxy-Adenosine 5'-phosphorate
• 5'-Adenylic Acid, 2'-Deoxy-, Ion(2-)
• dAMP.H2
• 2'-Deoxyadenosine 5'-Phosphate
• 2'-Deoxy-5'-adenylic acid
• 2'-Deoxy-5'-AMP
• 2'-Deoxyadenosine monophosphate
• 2'-Deoxyadenylic acid
• 2'-Deoxy-AMP
• 2'-Desoxyadenosin-5'-(dihydrogenphosphat)
• 5'-Adenylic acid, 2'-deoxy-
• 5'-dAMP
• 5'-Dihidrogenofosfato De 2'-Desoxiadenosina
• 5'-Dihydrogenophosphate De 2'-Desoxyadenosine
• Adenosine, 2'-deoxy-, 5'-(dihydrogen phosphate)
• dAMP
• Deoxyadenosine 5'-monophosphate
• Deoxyadenosine 5'-phosphate
• Deoxyadenosine monophosphate
• Deoxyadenylic acid
• Deoxy-AMP
• Nsc 77680
• Nsc 82625

2'-Deoxyadenosine-5'-monophosphate, 98%

CAS: 653-63-4

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Fórmula: C₁₀H₁₄N₅O₆P

Pureza: 98%

Peso molecular: 331.22

Ref: 02-J64402

5'-Adenylic acid, 2'-deoxy-

CAS: 653-63-4

Fórmula: C₁₀H₁₄N₅O₆P

Pureza: 95%

Forma y color: Solid

Peso molecular: 331.2218

Ref: IN-DA00IBHB

2'-Deoxyadenosine 5'-monophosphate

CAS: 653-63-4

2'-Deoxyadenosine 5'-monophosphate

Pureza: 98%

Peso molecular: 331.22g/mol

Ref: 54-OR1027552

2''-Deoxyadenosine-5''-monophosphate

CAS: 653-63-4

Fórmula: C₁₀H₁₄N₅O₆P

Peso molecular: 331.22

Ref: 7W-GE6112

2'-Deoxyadenosine-5'-monophosphate

CAS: 653-63-4

2'-Deoxyadenosine-5'-monophosphate

Pureza: ≥98%

Peso molecular: 331.22g/mol

Ref: 54-BUP14703

2'-Deoxyadenosine-5'-monophosphate

CAS: 653-63-4

2'-Deoxyadenosine-5'-monophosphate (D-AMP) is a nucleoside comprised of adenine attached to a ribose (ribofuranose) moiety via a -N9-glycosidic bond.

Fórmula: C₁₀H₁₄N₅O₆P

Pureza: 98% - 99.83%

Forma y color: Solid

Peso molecular: 331.22

Ref: TM-T4737

2’-Deoxyadenosine 5’Monophosphate

Producto controlado

CAS: 653-63-4

Applications 2’-Deoxyadenosine 5’Monophosphate is the first nucleotide of the phi 29 DNA.
References Shih, M.F., et. al.: Virology, 133, 56 (1984)

Fórmula: C₁₀H₁₄N₅O₆P

Forma y color: Neat

Peso molecular: 331.222

Ref: TR-D231630

2'-Deoxyadenosine-5'-monophosphate free acid

CAS: 653-63-4

2'-Deoxyadenosine-5'-monophosphate free acid (2DAMP) is a nucleoside analogue that can be used as a fluorescent probe for detecting water vapor. 2DAMP has been shown to have cytotoxic activity against solid tumours in vitro, and may act by hydrogen bonding interactions with the active site of the enzyme form. 2DAMP is also an important cofactor in the polymerase chain reaction, and can inhibit cellular proliferation by inhibiting nuclear DNA synthesis. This drug has been used as an active antiretroviral therapy, where it inhibits HIV-1 reverse transcriptase. 2DAMP's mechanism of action involves the inhibition of p-nitrophenyl phosphate reductase (PNPPR), which is responsible for converting p-nitrophenyl phosphate into p-nitrophenol.

Fórmula: C₁₀H₁₄N₅O₆P

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 331.23 g/mol

Ref: 3D-ND05971

2′-Deoxyadenosine-5′-monophosphate

CAS: 653-63-4

Fórmula: C₁₀H₁₄N₅O₆P

Pureza: 95%

Forma y color: Solid

Peso molecular: 331.225

Ref: 10-F236817