CAS 66-86-4

Neomicina C

Descripción:

Neomicina C, con el número CAS 66-86-4, es un antibiótico aminoglucósido que se deriva principalmente de la bacteria Streptomyces fradiae. Es conocido por su actividad antibacteriana de amplio espectro, particularmente contra bacterias Gram-negativas, y se utiliza a menudo en formulaciones tópicas para tratar infecciones. Neomicina C se caracteriza por su estructura compleja, que incluye múltiples azúcares amino unidos por enlaces glucosídicos, lo que contribuye a su mecanismo de acción que inhibe la síntesis de proteínas bacterianas. Este compuesto se administra típicamente de forma tópica o por inyección, ya que se absorbe mal del tracto gastrointestinal. Neomicina C puede causar efectos secundarios, incluyendo nefrotoxicidad y ototoxicidad, particularmente con el uso sistémico. Su solubilidad en agua lo hace adecuado para diversas aplicaciones farmacéuticas, pero es importante monitorear posibles reacciones alérgicas en individuos sensibles. En general, Neomicina C sigue siendo un antibiótico valioso en entornos clínicos, particularmente para infecciones localizadas.

Fórmula: C₂₃H₄₆N₆O₁₃

InChI: InChI=1/C23H46N6O13.ClH/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;/h5-23,30-36H,1-4,24-29H2;1H/t5-,6+,7-,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;/m1./s1

Clave InChI: InChIKey=PGBHMTALBVVCIT-VZXHOKRSSA-N

SMILES: O([C@H]1[C@H](O[C@H]2[C@H](O)[C@H](O[C@H]3O[C@H](CN)[C@@H](O)[C@H](O)[C@H]3N)[C@@H](CO)O2)[C@@H](O)[C@H](N)C[C@@H]1N)[C@H]4O[C@H](CN)[C@@H](O)[C@H](O)[C@H]4N

Sinónimos:

• Neomycin C
• D-Streptamine, O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)-O-[O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→3)-β-D-ribofuranosyl-(1→5)]-2-deoxy-
• O-2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine
• D-Streptamine, O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-
• Dekamycin II
• Neomycin EP Impurity
• Framycetin Impurity 3 (Framycetin EP Impurity C)
• 4-O-(2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl)-5-O-[3-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-β-D-ribofuranosyl]-2-deoxy-D-streptamine
• Framycetin EP Impurity C
• Framycetin sulfate EP Impurity C
• 5-amino-2-(aminomethyl)-6-[5-[3,5-diamino-2-[3-amino-6-(aminomethyl)-4 ,5-dihydroxy-oxan-2-yl]oxy-6-hydroxy-cyclohexyl]oxy-4-hydroxy-2-(hydro xymethyl)oxolan-3-yl]oxy-oxane-3,4-diol
• Neomycin C sulfate
• D-Streptamine, O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)-O-[O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→3)-β-D-ribofuranosyl-(1→5)]-2-deoxy-, monohydrochloride (9CI)

Neomycin EP Impurity C (Neomycin C)

CAS: 66-86-4

Fórmula: C₂₃H₄₆N₆O₁₃

Forma y color: Off-White Solid

Peso molecular: 614.65

Ref: 4Z-N-080016

Neomycin C

CAS: 66-86-4

Neomycin C, less potent isomer of Neomycin complex, is part of a 2-DOS aminoglycoside.

Fórmula: C₂₃H₄₆N₆O₁₃

Forma y color: Solid

Peso molecular: 614.64

Ref: TM-T73953

Neomycin EP Impurity C (Neomycin C) TFA Salt

CAS: 66-86-4

Fórmula: C₂₃H₄₆N₆O₁₃·xC₂HF₃O₂

Forma y color: Off-White Solid

Peso molecular: 614.65 x*114.02

Ref: 4Z-N-080005

Neomycin C Hexaacetate

CAS: 66-86-4

Stability Hygroscopic
Applications Neomycin C Hexaacetate is an aminoglycoside antibiotic found in many topical medications. Neomycin has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia.
References Umezawa, S., et al.: Bull. Chem. Soc. Jpm., 53, 3259 (1980); The Journal of antibiotics, NO. 2. 189 (1977);

Fórmula: C₂₃H₄₆N₆O₁₃•6(CH₃COOH)

Forma y color: Neat

Peso molecular: 614.6466005

Ref: TR-N389980

Neomycin EP impurity C (Neomycin C) trifluoroacetate

CAS: 66-86-4

Neomycin EP impurity C (Neomycin C) trifluoroacetate is a reference standard, which is a meticulously characterized chemical impurity often used in pharmaceutical analysis. This compound is derived from the fermentation of *Streptomyces fradiae*, which produces a complex mixture of aminoglycoside antibiotics, including Neomycin B and Neomycin C.

Fórmula: C₂₃H₄₆N₆O₁₃•(C₂HF₃O₂)x

Pureza: Min. 95%

Ref: 3D-AN183301

Neomycin C hexaacetate

CAS: 66-86-4

Please enquire for more information about Neomycin C hexaacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Fórmula: C₂₃H₄₆N₆O₁₃

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 614.6 g/mol

Ref: 3D-AAA06686

Neomycin sulfate EP Impurity C

CAS: 66-86-4

Fórmula: C₂₃H₄₆N₆O₁₃

Peso molecular: 614.65

Ref: ST-EA-CP-N53003