CAS 660846-97-9

Ac-Arg-Gly-Lys(Ac)-AMC

CAS: 660846-97-9

Ac-RGK(Ac)-AMC, fluorogenic substrate for assaying histone deacetylase (HDAC) activity in a two-step enzymatic reaction. The assay consists of the initial lysine deacetylation by HDAC followed by the release of the fluorescent group by trypsin.

Fórmula: C₂₈H₄₀N₈O₇

Pureza: > 99%

Forma y color: White Powder

Peso molecular: 600.68

Ref: 01-4044046

Ac-Arg-Gly-Lys(Ac)-MCA

CAS: 660846-97-9

Ac-Arg-Gly-Lys(Ac)-MCA is a peptide that is used as a histone deacetylase substrate. It is an enzyme substrate in the histone deacetylase reaction and it has been shown to inhibit the growth of many bacterial strains. Ac-Arg-Gly-Lys(Ac)-MCA has been shown to inhibit the growth of Staphylococcus aureus, Bacillus subtilis, and Pseudomonas aeruginosa.

Fórmula: C₂₈H₄₀N₈O₇

Pureza: Min. 95%

Peso molecular: 600.68 g/mol

Ref: 3D-SRK-3728-PI

Ac-Arg-Gly-Lys(Ac)-AMC trifluoroacetate salt

CAS: 660846-97-9

Ac-Arg-Gly-Lys(Ac)-AMC is a potent apoptotic agent that induces the apoptosis of cancer cells by binding to the caspase-9, which is an enzyme that initiates the process of apoptosis. Ac-Arg-Gly-Lys(Ac)-AMC has been shown to inhibit the growth of cancer cells in cell culture and also shows potent antitumor activity against MDA-MB-231 breast cancer cells. This drug can be used as a potential therapeutic agent for cancers such as colorectal, prostate, and pancreatic cancer. Ac-Arg-Gly-Lys(Ac)-AMC is also able to induce apoptosis in human leukemia cells and may have a potential role in therapy for acute myelogenous leukemia (AML).

Fórmula: C₂₈H₄₀N₈O₇•C₂HF₃O₂

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 714.69 g/mol

Ref: 3D-FA110598