CAS 66575-29-9

Forskolina

Descripción:

Forskolina es un compuesto natural derivado de la raíz de la planta Coleus forskohlii, un miembro de la familia de las mentas. Se clasifica como un diterpeno labdano y es conocido por su estructura química distintiva, que incluye un marco bicíclico. Forskolina es reconocido por su capacidad para activar la adenilato ciclasa, una enzima que aumenta los niveles de monofosfato de adenosina cíclica (cAMP) en las células, lo que conduce a varios efectos fisiológicos. Este mecanismo ha despertado interés en los campos de la farmacología y la bioquímica, particularmente por sus posibles aplicaciones en el control del peso, la salud cardiovascular y el tratamiento del asma. Forskolina está disponible típicamente en varias formas, incluyendo polvos y extractos, y a menudo se comercializa como un suplemento dietético. Su solubilidad es principalmente en disolventes orgánicos y presenta un perfil de toxicidad relativamente bajo. Sin embargo, al igual que con cualquier suplemento, es esencial consultar a profesionales de la salud antes de usarlo, especialmente para individuos con condiciones de salud subyacentes o aquellos que toman otros medicamentos.

Fórmula: C₂₂H₃₄O₇

InChI: InChI=1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1

Clave InChI: InChIKey=OHCQJHSOBUTRHG-KGGHGJDLSA-N

SMILES: O[C@@]12[C@]3(C)[C@@]([C@H](O)[C@H](OC(C)=O)[C@@]1(C)O[C@](C=C)(C)CC2=O)(C(C)(C)CC[C@@H]3O)[H]

Sinónimos:

• (3R,4aR,5S,6S,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-5-yl acetate
• (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one
• (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-Dodecahydro-5,6,10,10b-tetrahydroxy-3,4a,7,7,10a-pentamethyl-3-vinyl-1H-naphtho(2,1-b)pyran-1-one 5-acetate
• 1H-Naphtho(2,1-b)pyran-1-one, 5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-, (3R-(3alpha,4abeta,5beta,6beta,6aalpha,10alpha,10abeta,10balpha))-
• 1H-Naphtho(2,1-b)pyran-1-one, dodecahydro-5-(acetyloxy)-3-ethenyl-3,4a,7,7,10a-pentamethyl-6,10,10b-trihydroxy-, (3R-(3-alpha,4a-beta,5-beta,6-beta,6a-alpha,10-alpha,10a-beta,10b-alpha))-
• 1H-Naphtho[2,1-b]pyran-1-one, 5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-
• 1H-Naphtho[2,1-b]pyran-1-one, 5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-, [3R-(3α,4aβ,5β,6β,6aα,10α,10aβ,10bα)]-
• 3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-5-yl acetate
• 7-beta-Acetoxy-8,13-epoxy-1-alpha,6-beta,9-alpha-trihydroxylabd-14-en-11-one
• Boforsin
• Coleonol
• Colforsina
• Colforsina [Spanish]
• Colforsine
• Colforsine [French]
• Colforsinum
• Colforsinum [Latin]
• ForsLean
• Forskolin
• Hl 362
• L 75 1362B
• M 410
• Nsc 357088
• Nsc 375489

Forskolin

CAS: 66575-29-9

Fórmula: C₂₂H₃₄O₇

Pureza: >95.0%(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 410.51

Ref: 3B-F0855

Forskolin, 98+%

CAS: 66575-29-9

Forskolin (coleonol), 66575-29-9, is a labdane diterpenoid isolated from the Indian Coleus plant which acts as an adenylyl cyclase activator. Learn more.

Fórmula: C₂₂H₃₄O₇

Pureza: 98+%

Forma y color: Powder, White

Peso molecular: 410.51

Ref: 02-J63292

Forskolin

CAS: 66575-29-9

Forskolin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₂₂H₃₄O₇

Pureza: (HPLC) ≥99%

Forma y color: Powder

Peso molecular: 410.51

Ref: 11-3733S

Forskolin (7β-acetoxy-8,13-epoxy-1α,6β,9α-trihydroxy-labd-14-en-11-one)

CAS: 66575-29-9

Heterocyclic compounds with oxygen hetero-atom(s) only nesoi

Fórmula: C₂₂H₃₄O₇

Forma y color: White Crystalline Powder

Peso molecular: 410.23045

Ref: 45-1283244

Forskolin

CAS: 66575-29-9

Fórmula: C₂₂H₃₄O₇

Pureza: 97%

Forma y color: Solid

Peso molecular: 410.5012

Ref: IN-DA003QOW

Forskolin

CAS: 66575-29-9

Forskolin

Pureza: ≥98%

Peso molecular: 410.5g/mol

Ref: 54-BUP17787

Forskolin from coleus forskohlii

CAS: 66575-29-9

Forskolin from coleus forskohlii

Fórmula: C₂₂H₃₄O₇

Pureza: By hplc: >98% (Typical Value in Batch COA)

Forma y color: white powder

Peso molecular: 410.50g/mol

Ref: 54-BIF1031

Forskolin

CAS: 66575-29-9

Fórmula: C₂₂H₃₄O₇

Pureza: ≥ 98.0% (anhydrous basis)

Forma y color: White to off-white powder

Peso molecular: 410.51

Ref: 7W-GP2059

Forskolin

CAS: 66575-29-9

Oridonin has anticancer activity, might be useful as adjunctive therapy for individuals with lymphoid malignancies, including the lethal disease adult T-cell leukemia.It inhibits tumor growth in glioma by inducing cell cycle arrest and apoptosis, inhibits BxPC-3 cell growth through cell apoptosis.

Fórmula: C₂₂H₃₄O₇

Pureza: 95%~99%

Peso molecular: 410.507

Ref: BP-BP0593

Forskolin

CAS: 66575-29-9

Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM).

Fórmula: C₂₂H₃₄O₇

Pureza: 98.83% - 99.96%

Forma y color: Less Crystalline Solid Colorless Crystalline Solid

Peso molecular: 410.50

Ref: TM-T2939

Forskolin

CAS: 66575-29-9

Fórmula: C₂₂H₃₄O₇

Peso molecular: 410.51

Ref: 4Z-F-238001

Forskolin

CAS: 66575-29-9

Oxygen-heterocyclic compound

Fórmula: C₂₂H₃₄O₇

Pureza: ≥ 98.0 % (HPLC)

Forma y color: Powder

Peso molecular: 410.51

Ref: 5G-89664

Forskolin

CAS: 66575-29-9

Applications Forskolin is a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cAMP.
References Lindner, E., et al.: Arzneim.-Forsch., 28, 284 (1984), Hoever, G., et al.: J. Med. Chem., 48, 1256 (2005), Lai, S., et al.: Eur. J. Clin. Microbiol. Infect. Dis., 24, 5831 (2005),

Fórmula: C₂₂H₃₄O₇

Forma y color: Neat

Peso molecular: 410.50

Ref: TR-F701800

Forskolin

CAS: 66575-29-9

Forskolin is a diterpene compound from Asian medicinal plant Coleus forskohlii. It is an activator of adenylate cyclase, causing increase in cellular levels of cAMP. It has anti-neuroinflammatory activity since it reduced microglial activation and astrocyte activation in the brain of rodent models for cerebral amyloidosis. Forskolin also reduced amyloid beta plaques deposition in cortex and hippocampus.

Fórmula: C₂₂H₃₄O₇

Pureza: Min. 97 Area-%

Forma y color: White Off-White Powder

Peso molecular: 410.5 g/mol

Ref: 3D-FF23593

Forskolin - Bio-X ™

CAS: 66575-29-9

Forskolin is a compound derived from the medicinal plant Coleus forskohlii. As an activator of adenylate cyclase, Forskolin causes increases cellular levels of cAMP, and can be used in cell physiology research. It also has antihypertensive, platelet aggregation inhibitory and smooth muscle relaxant effects.

Fórmula: C₂₂H₃₄O₇

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 410.5 g/mol

Ref: 3D-BF164487

Forskolin

CAS: 66575-29-9

Pureza: 97%

Peso molecular: 410.51

Ref: 10-M04088