CAS 66852-54-8
:Propionato de halobetasol
Descripción:
Propionato de halobetasol es un corticosteroide sintético utilizado principalmente por sus propiedades antiinflamatorias e inmunosupresoras, particularmente en aplicaciones dermatológicas. Se caracteriza por su alta potencia, lo que lo hace efectivo en el tratamiento de diversas afecciones cutáneas como la psoriasis y el eczema. La sustancia es un polvo cristalino blanco a blanco amarillento que es prácticamente insoluble en agua pero soluble en disolventes orgánicos. Su mecanismo de acción implica la inhibición de mediadores inflamatorios, reduciendo así el enrojecimiento, la hinchazón y la picazón asociadas con trastornos de la piel. Propionato de halobetasol se formula típicamente en preparaciones tópicas, incluyendo cremas, ungüentos y lociones, y se aplica directamente en el área afectada. Debido a su potencia, generalmente se recomienda su uso a corto plazo y bajo supervisión médica para minimizar los posibles efectos secundarios, como el adelgazamiento de la piel o la absorción sistémica. Al igual que con todos los corticosteroides, se deben seguir las pautas de uso adecuadas para garantizar la seguridad y la eficacia.
Fórmula:C25H31ClF2O5
InChI:InChI=1S/C25H31ClF2O5/c1-5-21(32)33-25(20(31)12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15-,16-,18-,19-,22-,23-,24-,25-/m0/s1
Clave InChI:InChIKey=BDSYKGHYMJNPAB-LICBFIPMSA-N
SMILES:O(C(CC)=O)[C@@]1(C(CCl)=O)[C@]2(C)[C@@](C[C@@H]1C)([C@]3([C@](F)([C@@H](O)C2)[C@]4(C)C([C@@H](F)C3)=CC(=O)C=C4)[H])[H]
Sinónimos:- (6α,11β,16β)-21-Chloro-6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
- Bmy 30056
- Cgp 14458
- Halobetasol propionate
- Miracorten
- Ulobetasol propionate
- Ultravate
- ethyl (6alpha,11beta,16beta)-21-chloro-6,9-difluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-diene-17-carboxylate
- (6alpha,8xi,10xi,13xi,14xi,16beta)-21-chloro-6,9-difluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl propanoate
- 21-Chloro-6alpha,9-difluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate
- (6alpha,11beta,16beta)-21-chloro-6,9-difluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl propanoate
- Ver más sinónimos
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Encontrado 15 productos.
Halobetasol Propionate
CAS:Fórmula:C25H31ClF2O5Pureza:>98.0%(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:484.96Halobetasol Propionate
CAS:Halogenated derivatives of adrenal cortical hormonesFórmula:C25H31ClF2O5Forma y color:White Off-White PowderPeso molecular:484.18281Halobetasol-d3 Propionate
CAS:Fórmula:C25H28D3ClF2O5Forma y color:White To Off-White SolidPeso molecular:487.98Halobetasol Propionate-d5
CAS:Fórmula:C25H26D5ClF2O5Forma y color:White To Off-White SolidPeso molecular:490.00Halobetasol Propionate
CAS:Producto controladoFórmula:C25H31ClF2O5Forma y color:NeatPeso molecular:484.96Halobetasol propionate
CAS:Halobetasol propionate (BMY-30056) is the salt of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities.
Fórmula:C25H31ClF2O5Pureza:99.89%Forma y color:Distributed As 0 05% OintmentPeso molecular:484.96Halobetasol Propionate
CAS:Producto controladoApplications Anti-inflammatory; a dermatologic agent commonly used to treat psoriasis
References Pearce, D., et al.: Int. J. Dermatol., 45, 370 (2006),Fórmula:C25H31ClF2O5Forma y color:NeatPeso molecular:484.96Halobetasol Propionate-d5
CAS:Producto controladoFórmula:C25D5H26ClF2O5Forma y color:NeatPeso molecular:489.991Halobetasol propionate
CAS:Producto controladoHalobetasol propionate is a corticosteroid that is used to treat inflammatory skin diseases such as psoriasis and atopic dermatitis. It belongs to the group of drugs known as topical steroids, which are applied to the skin. Halobetasol propionate may also be used to treat choroidal neovascularization (CNV) or ocular hypertension in patients with age-related macular degeneration, but it is not approved for this use. The mechanism of action of halobetasol propionate is not fully understood, but it has been shown to inhibit the activity of certain proteins involved in inflammation. Halobetasol propionate has been shown to be more effective than hydrocortisone in reducing the severity and frequency of cutaneous lesions in patients with psoriasis.Fórmula:C25H31ClF2O5Pureza:Min. 95%Forma y color:PowderPeso molecular:484.96 g/molHalobetasol propionate-d3
CAS:Producto controladoHalobetasol propionate-d3 is a biocompatible polymer that binds to the effector proteins of the inflammatory response. It is used in the treatment of inflammatory bowel disease, psoriasis, and other skin diseases. Halobetasol propionate-d3 has been shown to be effective against plaque and cutaneous lesions in patients with psoriasis. This drug also inhibits the production of proinflammatory cytokines (IL-1β, IL-6, IL-8) and chemokines (MCP-1) by monocytes. The drug has been shown to be effective against autoimmune diseases due to its ability to inhibit TNFα production from macrophages. Halobetasol propionate-d3 is compatible with blood group A, B, and AB.
Fórmula:C25H31ClF2O5Pureza:Min. 95%Peso molecular:484.96 g/molRef: 3D-FH57683
Producto descatalogado
