CAS 66898-62-2

Talniflumato

Descripción:

Talniflumato es un compuesto químico clasificado como un fármaco antiinflamatorio no esteroideo (AINE) utilizado principalmente por sus propiedades analgésicas y antiinflamatorias. Se caracteriza por su capacidad para inhibir la síntesis de prostaglandinas, que son mediadores de la inflamación y el dolor. Talniflumato se utiliza a menudo en el tratamiento de diversas condiciones inflamatorias, incluyendo la artritis y otros trastornos musculoesqueléticos. El compuesto exhibe una solubilidad moderada a alta en disolventes orgánicos, lo que puede influir en su biodisponibilidad y farmacocinética. Su mecanismo de acción implica la modulación de las enzimas ciclooxigenasas, lo que lleva a una reducción de la inflamación y al alivio del dolor. Además, Talniflumato puede tener un perfil de seguridad favorable en comparación con los AINE tradicionales, con una menor incidencia de efectos secundarios gastrointestinales. Sin embargo, como todos los medicamentos, debe usarse bajo supervisión médica, considerando posibles interacciones y contraindicaciones. En general, Talniflumato representa una opción valiosa en el manejo del dolor y la inflamación en entornos clínicos.

Fórmula: C₂₁H₁₃F₃N₂O₄

InChI: InChI=1S/C21H13F3N2O4/c22-21(23,24)12-5-3-6-13(11-12)26-17-16(9-4-10-25-17)19(28)30-20-15-8-2-1-7-14(15)18(27)29-20/h1-11,20H,(H,25,26)

Clave InChI: InChIKey=ANMLJLFWUCQGKZ-UHFFFAOYSA-N

SMILES: O(C(=O)C1=C(NC2=CC(C(F)(F)F)=CC=C2)N=CC=C1)C3C=4C(C(=O)O3)=CC=CC4

Sinónimos:

• (3-Oxo-1H-2-benzofuran-1-yl) 2-[3-(trifluoromethyl)anilino]pyridine-3-carboxylate
• 2-(3-Trifluoromethyl-phenylamino)-nicotinic acid 3-oxo-1,3-dihydro-isobenzofuran-1-yl ester
• 2-[[3-(Trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic Acid 1,3-Dihydro-3-oxo-1-isobenzofuranyl Ester
• 3-Oxo-1,3-Dihydro-2-Benzofuran-1-Yl 2-{[3-(Trifluoromethyl)Phenyl]Amino}Pyridine-3-Carboxylate
• 3-Oxo-1,3-dihydro-2-benzofuran-1-yl 2-{[3-(trifluoromethyl)phenyl]amino}nicotinate
• 3-Pyridinecarboxylic acid, 2-[[3-(trifluoromethyl)phenyl]amino]-, 1,3-dihydro-3-oxo-1-isobenzofuranyl ester
• 66898-62-2
• Ba 7602-06
• Sml 1710
• Somalgen
• Talniflumate
• Talniflumate (BA 7602-06)
• 3-pyridinecarboxylic acid 2-{[(3-trifluoromethyl)phenyl]amino}-1,3-dihydro-3-oxo-1-soenzofuranyl ester
• TALNIFLUMATE(INTERMEDIATE)
• 3-ftalidilicodelacido2-((3-(trifluormetil)fenil)amino)-3-piridincarboxilic
• 2-[[3-(Trifluoromethyl)phenyl]amino]-1,3-dihydro-3-oxo-1-isobenzofuranyl3-pyridinecarboxylicacidester
• phthalidyl2-(3-trifluoromethylanilino)nicotinate
• 2-(alpha,alpha,alpha-trifluoro-m-toluidino)-nicotinicaciphthalidylester
• 2-[3-(trifluoromethyl)anilino]-3-pyridinecarboxylic acid (3-oxo-1H-isobenzofuran-1-yl) ester
• 2-(α,α,α-Trifluoro-m-toluidino)nicotinic acid phthalidyl ester
• phthalidyl2-(alpha,alpha,alpha-trifluoro-m-toluidino)nicotinate
• 2-(alpha,alpha,alpha-trifluoro-m-toluidino)nicotinicacidphthalidylester
• 3-phthalidylesterof2-((3-(trifluoromethyl)phenyl)amino)-3-pyridinecarboxyl
• 2-[[3-(Trifluoromethyl)phenyl]amino]nicotinic acid 1,3-dihydro-3-oxoisobenzofuran-1-yl ester
• Talniflumate, >=99%

Talniflumate

CAS: 66898-62-2

Fórmula: C₂₁H₁₃F₃N₂O₄

Pureza: >98.0%(HPLC)(N)

Forma y color: White to Yellow powder to crystal

Peso molecular: 414.34

Ref: 3B-T3101

[(1R)-3-oxo-1H-2-benzofuran-1-yl] 2-[3-(trifluoromethyl)anilino]pyridine-3-carboxylate

CAS: 66898-62-2

Fórmula: C₂₁H₁₃F₃N₂O₄

Pureza: 98%

Forma y color: Solid

Peso molecular: 414.3341

Ref: IN-DA00IMKI

Talniflumate

CAS: 66898-62-2

Talniflumate

Pureza: 98%

Peso molecular: 414.34g/mol

Ref: 54-PC108958

Talniflumate

CAS: 66898-62-2

Talniflumate

Pureza: ≥98%

Peso molecular: 414.33g/mol

Ref: 54-BUP05375

Talniflumate

CAS: 66898-62-2

Talniflumate (Somalgen) is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and releases in animal models and cell

Fórmula: C₂₁H₁₃F₃N₂O₄

Pureza: 98% - 99.81%

Forma y color: White To Pale Yellow Crystalline Powder

Peso molecular: 414.33

Ref: TM-T4503

Talniflumate

Producto controlado

CAS: 66898-62-2

Stability Acid Sensitive, Moisture Sensitive
Applications Talniflumate is a nonaspirin and nonsteroidal anti-inflammatory drug.
References Choi, N., et al.: Stroke, 39, 845 (2008)

Fórmula: C₂₁H₁₃F₃N₂O₄

Forma y color: Off White To Light Green

Peso molecular: 414.33

Ref: TR-T005575

Talniflumate

CAS: 66898-62-2

Talniflumate is a fatty acid that is chemically similar to the natural product linoleic acid. It has been shown to be effective at preventing and treating infections caused by infectious diseases, such as malaria and tuberculosis. Talniflumate has also been used in the treatment of autoimmune diseases like psoriasis and systemic lupus erythematosus. Talniflumate has low bioavailability, which may be due to its high lipophilicity or a lack of solubility in water. The analytical method for talniflumate is based on an LC-MS/MS technique that uses nanocapillary columns with high resolution mass spectrometry detection. This method can measure concentrations as low as 10 ng/mL of talniflumate in biological samples.

Fórmula: C₂₁H₁₃F₃N₂O₄

Pureza: Min. 95%

Forma y color: White Clear Liquid

Peso molecular: 414.33 g/mol

Ref: 3D-FT60430

TALNIFLUMATE

CAS: 66898-62-2

Pureza: 98%

Peso molecular: 414.3399963

Ref: 10-F801738