CAS: 675576-98-4 - 4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-Piperazinone

Fórmula: C₃₀H₃₀Cl₂N₄O₄

InChI: InChI=1S/C30H30Cl2N4O4/c1-18(2)40-25-16-23(39-3)12-13-24(25)29-34-27(19-4-8-21(31)9-5-19)28(20-6-10-22(32)11-7-20)36(29)30(38)35-15-14-33-26(37)17-35/h4-13,16,18,27-28H,14-15,17H2,1-3H3,(H,33,37)/t27-,28+/m0/s1

Clave InChI: InChIKey=BDUHCSBCVGXTJM-WUFINQPMSA-N

SMILES: O=C1NCCN(C(=O)N2C(=NC(C3=CC=C(Cl)C=C3)C2C4=CC=C(Cl)C=C4)C=5C=CC(OC)=CC5OC(C)C)C1

Sinónimos:

• (-)-Nutlin 3
• 2-Piperazinone, 4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-
• 4-[[(4S,5R)-4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydroimidazol-1-yl]carbonyl]piperazin-2-one
• Nutlin-3a
• Piperazinone, 4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-
• Sml 0580

4-[[(4S,5R)-4,5-Bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-piperazinone

CAS: 675576-98-4

• Fórmula: C₃₀H₃₀Cl₂N₄O₄
• Pureza: ≥97%
• Forma y color: Solid
• Peso molecular: 581.4896

Nutlin-3a

CAS: 675576-98-4

Nutlin-3a ((−)-Nutlin-3), the active enantiomer of Nutlin-3, inhibits MDM2-p53 interactions and stabilizes the p53 protein.

• Fórmula: C₃₀H₃₀Cl₂N₄O₄
• Pureza: 98.73%
• Forma y color: Solid
• Peso molecular: 581.49

MDM2 Antagonist IV, Nutlin-3a

CAS: 675576-98-4

Nutlin-3a is a potent and selective inhibitor of the MDM2 protein, which is an important …

• Fórmula: C₃₀H₃₀Cl₂N₄O₄
• Pureza: Min. 95%
• Peso molecular: 581.49 g/mol