CAS 67869-62-9

acetato de glicina-prolina-arginina-prolina

Descripción:

acetato de glicina-prolina-arginina-prolina, identificado por su número CAS 67869-62-9, es un péptido sintético compuesto por cuatro aminoácidos: glicina (Gly), prolina (Pro), arginina (Arg) y otra prolina (Pro). Este péptido exhibe características típicas de los péptidos, incluyendo un peso molecular relativamente bajo y la capacidad de formar estructuras secundarias específicas debido a la presencia de prolina, que puede inducir giros en las cadenas de péptidos. El componente acetato indica que el péptido está probablemente en su forma de sal de acetato, lo que puede mejorar su solubilidad en soluciones acuosas. acetato de glicina-prolina-arginina-prolina puede exhibir actividad biológica, potencialmente influyendo en procesos como la señalización celular o la modulación de funciones fisiológicas, aunque los roles biológicos específicos dependerían del contexto de su uso. Su estabilidad, solubilidad y reactividad pueden verse influenciadas por factores como el pH y la temperatura. Al igual que muchos péptidos, también puede estar sujeto a degradación enzimática, lo cual es una consideración importante en su aplicación en contextos de investigación o terapéuticos.

Fórmula: C₁₈H₃₁N₇O₅

InChI: InChI=1/C18H31N7O5/c19-10-14(26)24-8-2-5-12(24)15(27)23-11(4-1-7-22-18(20)21)16(28)25-9-3-6-13(25)17(29)30/h11-13H,1-10,19H2,(H,23,27)(H,29,30)(H4,20,21,22)

SMILES: C(CC(C(=O)N1CCCC1C(=O)O)N=C(C1CCCN1C(=O)CN)O)CNC(=N)N

Sinónimos:

• H-Gly-Pro-Arg-Pro-OH
• glycyl-L-prolyl-N~5~-(diaminomethylidene)-L-ornithyl-L-proline
• glycylprolyl-N~5~-(diaminomethylidene)ornithylproline
• Gly-Pro-Arg-Pro

H-Gly-Pro-Arg-Pro-OH

CAS: 67869-62-9

GPRP (H-2935) inhibits fibrinogen/thrombin clotting, though it is less active than its C-terminal amide GPRP-NH₂.

Fórmula: C₁₈H₃₁N₇O₅

Pureza: 97.4%

Forma y color: White

Peso molecular: 425.49

Ref: 01-4004545

GPRP

CAS: 67869-62-9

GPRP (Gly-Pro-Arg-Pro) is a fibrin polymerization inhibitor.

Fórmula: C₁₈H₃₁N₇O₅

Forma y color: White To Off-White Powder

Peso molecular: 425.48

Ref: TM-T27419

H-Gly-Pro-Arg-Pro-OH

Producto controlado

CAS: 67869-62-9

H-Gly-Pro-Arg-Pro-OH is a sealant that has been shown to be effective in the treatment of bowel disease. It is a calcium binding compound that can be administered topically or systemically. H-Gly-Pro-Arg-Pro-OH has clinical relevance in vivo with human beings and exhibits ATP levels that are similar to those found in normal tissue. The surface glycoprotein of this compound has been shown to have an affinity for epidermal growth factor, which may play a role in inflammatory bowel disease. HGPAROH is activated by fibrinogen, which leads to its bound form being recognized by monoclonal antibody as well as the human serum proteins (e.g., albumin).

Fórmula: C₁₈H₃₁N₇O₅

Pureza: Min. 95%

Peso molecular: 425.48 g/mol

Ref: 3D-INH-3797-PI

Fibrinolysis Inhibitng Factor

CAS: 67869-62-9

Fibrinolysis Inhibiting Factor is a surface glycoprotein that belongs to the group of human serum proteins. It has been shown to be involved in the pathogenesis of bowel diseases and is a target for dextran sulfate. Fibrinolysis inhibiting factor binds to the surfaces of cells and blocks blood coagulation by interfering with the conversion of fibrinogen into fibrin. The protein also binds calcium ions and prevents them from being deposited on cell surfaces, thereby preventing inflammatory reactions such as inflammation of the bowel. Fibrinolysis inhibiting factor has been shown to activate monoclonal antibodies in vitro, which may explain its effect on inflammatory bowel disease.

Fórmula: C₁₈H₃₁N₇O₅

Pureza: Min. 95%

Peso molecular: 425.48 g/mol

Ref: 3D-FF73385