CAS 68-23-5

Noretinodrel

Descripción:

Noretinodrel es un progestágeno sintético, utilizado principalmente en anticonceptivos hormonales y terapia de reemplazo hormonal. Se caracteriza por su capacidad para imitar los efectos de la progesterona natural, regulando así diversas funciones reproductivas. La fórmula molecular de Noretinodrel indica que contiene átomos de carbono, hidrógeno y oxígeno, lo que contribuye a su estructura esteroidal. Este compuesto se administra típicamente por vía oral y es conocido por su efectividad en la prevención de la ovulación, alterando el ciclo menstrual y proporcionando protección endometrial. Noretinodrel exhibe una lipofilia moderada, lo que influye en su absorción y distribución en el cuerpo. Su perfil farmacológico incluye efectos secundarios potenciales como aumento de peso, cambios de humor y alteraciones en los patrones menstruales. Además, es importante considerar sus contraindicaciones e interacciones con otros medicamentos. Al igual que con cualquier tratamiento hormonal, el monitoreo cuidadoso y la consulta con un proveedor de atención médica son esenciales para garantizar un uso seguro y efectivo. En general, Noretinodrel desempeña un papel significativo en la gestión de la salud reproductiva.

Fórmula: C₂₀H₂₆O₂

InChI: InChI=1S/C20H26O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h1,16-18,22H,4-12H2,2H3/t16-,17-,18+,19+,20+/m1/s1

Clave InChI: InChIKey=ICTXHFFSOAJUMG-SLHNCBLASA-N

SMILES: C[C@@]12[C@]([C@]3([C@](CC1)(C4=C(CC3)CC(=O)CC4)[H])[H])(CC[C@]2(C#C)O)[H]

Sinónimos:

• (17Beta)-17-Ethynyl-17-Hydroxyestr-5(10)-En-3-One
• (17α)-17-Hydroxy-19-norpregn-5(10)-en-20-yn-3-one
• (8Xi,9Xi,14Xi,17Beta)-17-Ethynyl-17-Hydroxyestr-5(10)-En-3-One
• 13-Methyl-17-ethynyl-17-hydroxy-1,2,3,4,6,7,8,9,11,12,13,14,16,17-tetradecahydro-15H-cyclopenta[a]phenanthren-3-one
• 17-Beta-Hydroxy-19-Nor-17-Alpha-Pregn-5(10)-En-20-Yn-3-One
• 17-Ethynyl-17-Hydroxyestr-5(10)-En-3-One
• 17-Hydroxy-19-nor-17α-pregn-5(10)-en-20-yn-3-one
• 17α-Ethinyl-17β-hydroxy-Δ⁵(¹⁰)-estren-3-one
• 17α-Ethynyl-17-hydroxy-5(10)-estren-3-one
• 17α-Ethynyl-17β-hydroxy-5(10)-estrene-3-one
• 17α-Ethynyl-17β-hydroxy-Δ⁵⁽¹⁰⁾-estren-3-one
• 17α-Ethynylestr-5(10)-ene-17β-ol-3-one
• 17α-Ethynylestra-5(10)-ene-17β-ol-3-one
• 17β-Hydroxy-19-nor-17α-pregn-5(10)-en-20-yn-3-one
• 19-Nor-17α-pregn-5(10)-en-20-yn-3-one, 17-hydroxy-
• 19-Norpregn-5(10)-en-20-yn-3-one, 17-hydroxy-, (17α)-
• 3-Oxo-17β-hydroxy-17α-ethynyl-5(10)-estrene
• Enidrel
• NSC 15432
• Norethinodrel
• Noretynodrel
• Sc 4642

Norethynodrel

CAS: 68-23-5

Forma y color: Neat

Ref: 61-FOR1170.00

Norethynodrel

CAS: 68-23-5

Norethynodrel

Pureza: ≥95%

Peso molecular: 298.42g/mol

Ref: 54-OR1075454

Norethynodrel

CAS: 68-23-5

Fórmula: C₂₀H₂₆O₂

Forma y color: White To Off-White Solid

Peso molecular: 298.43

Ref: 4Z-N-511

Norethynodrel

CAS: 68-23-5

Norethynodrel, a synthetic hormone, mimics progesterone, treats uterine bleeding/endometriosis, and is used with mestranol as a contraceptive.

Fórmula: C₂₀H₂₆O₂

Pureza: 98%

Forma y color: Crystals From Aqueous Methanol Solid

Peso molecular: 298.42

Ref: TM-T0171

Norethynodrel

CAS: 68-23-5

Impurity Norethindrone EP Impurity D
Applications Norethynodrel (Norethindrone EP Impurity D) is a progestin used in Enovid, an oral contraceptive, also used in the treatment of endometriosis and hypermenorrhea.
References Palmer K., et al.: J. Pharmacol. Exp. Ther., 167, 207 (1969), Liu, L., et al.: Endocrinology., 151, 5782 (2010), Sonneveld, E., et al.: Toxicol. in Vitro, 25, 545 (2011)

Fórmula: C₂₀H₂₆O₂

Pureza: >90%

Forma y color: Off-White

Peso molecular: 298.42

Ref: TR-N676020

Norethynodrel

Producto controlado

CAS: 68-23-5

Norethynodrel is a progestin that is used in combination with other drugs to prevent pregnancy. It works by inhibiting ovulation, thickening cervical mucus to inhibit sperm penetration, and altering the uterine lining. This drug has been shown to have carcinogenic potential in animal models and can lead to myocardial infarcts. Norethynodrel binds competitively to the receptor site of estradiol benzoate or estradiol, preventing it from binding and activating the estrogen-dependent response. This mechanism of action also inhibits the enzyme activity of 17β-hydroxysteroid dehydrogenase type II (17βHSD2) and reductase activity of 3βHSD, which are involved in hormone synthesis. The lack of these two enzymes leads to an accumulation of estrogens, which may contribute to carcinogenic effects.

Fórmula: C₂₀H₂₆O₂

Pureza: Min. 96 Area-%

Forma y color: Powder

Peso molecular: 298.42 g/mol

Ref: 3D-FN26448

Norethynodrel

CAS: 68-23-5

Pureza: 98%

Peso molecular: 298.4259949

Ref: 10-F600857

Norethindrone EP Impurity D

CAS: 68-23-5

Fórmula: C₂₀H₂₆O₂

Peso molecular: 298.43

Ref: ST-EA-CP-N51004