CAS 68406-26-8

Ginsenósido Rb3

Descripción:

Ginsenósido Rb3 es un saponina triterpenoide que se encuentra principalmente en el ginseng, una planta conocida por sus propiedades medicinales. Es uno de los muchos ginsenósidos, que son los compuestos activos que se cree que contribuyen a los beneficios para la salud del ginseng. Ginsenósido Rb3 se caracteriza por su compleja estructura molecular, que incluye un esqueleto similar a un esteroide con múltiples moieties de azúcar adjuntas, lo que influye en su solubilidad y bioactividad. Este compuesto es conocido por sus posibles efectos farmacológicos, que incluyen propiedades antiinflamatorias, antioxidantes y neuroprotectoras. La investigación sugiere que Ginsenósido Rb3 puede mejorar la función cognitiva y exhibir efectos cardioprotectores, lo que lo hace de interés tanto en la medicina tradicional como en la farmacología moderna. Su mecanismo de acción a menudo implica la modulación de varias vías de señalización, contribuyendo a su potencial terapéutico. Al igual que con muchos compuestos naturales, la biodisponibilidad y la eficacia de Ginsenósido Rb3 pueden verse influenciadas por factores como la dosis, la formulación y las diferencias metabólicas individuales.

Fórmula: C₅₃H₉₀O₂₂

InChI: InChI=1/C53H90O22/c1-8-23(2)10-9-15-53(7,75-48-44(67)40(63)38(61)31(72-48)22-69-46-42(65)35(58)28(57)21-68-46)25-13-16-52(6)24-11-12-32-50(3,4)33(14-17-51(32,5)26(24)18-27(56)34(25)52)73-49-45(41(64)37(60)30(20-55)71-49)74-47-43(66)39(62)36(59)29(19-54)70-47/h10,24-49,54-67H,8-9,11-22H2,1-7H3/b23-10+/t24?,25?,26?,27-,28+,29+,30+,31+,32?,33?,34?,35-,36+,37+,38+,39-,40+,41-,42+,43+,44+,45+,46-,47-,48-,49-,51+,52+,53+/m0/s1

Clave InChI: InChIKey=NODILNFGTFIURN-USYOXQFSSA-N

SMILES: C[C@]12[C@@]3(C)[C@@]([C@@]([C@@](O[C@@H]4O[C@H](CO[C@H]5[C@H](O)[C@@H](O)[C@H](O)CO5)[C@@H](O)[C@H](O)[C@H]4O)(CCC=C(C)C)C)(CC3)[H])([C@H](O)C[C@@]1([C@]6(C)[C@@](CC2)(C(C)(C)[C@@H](O[C@H]7[C@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@@H](CO)O7)CC6)[H])[H])[H]

Sinónimos:

• (1R,4E)-1-{(8xi,9xi,12α,13xi,14β)-3-[(2-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxy-4,4,10,14-tetramethylgonan-17-yl}-1,5-dimethylhept-4-en-1-yl 6-O-β-D-xylopyranosyl-β-D-allopyranoside
• (3β,12β)-3-[(2-O-β-<span class="text-smallcaps">D</smallcap>-Glucopyranosyl-β-<smallcap>D</smallcap>-glucopyranosyl)oxy]-12-hydroxydammar-24-en-20-yl 6-O-β-<smallcap>D</smallcap>-xylopyranosyl-β-<smallcap>D</span>-glucopyranoside
• Dammarane, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• Ginsenoside Rb₃
• Gypenoside IV
• alpha-D-Glucopyranoside, (3-beta,12-beta)-3-((2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy)-12-hydroxydammar-24-en-20-yl 6-O-beta-D-xylopyranosyl-
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,12β)-3-[(2-O-β-<smallcap>D</smallcap>-glucopyranosyl-β-<smallcap>D</smallcap>-glucopyranosyl)oxy]-12-hydroxydammar-24-en-20-yl 6-O-β-<smallcap>D</span>-xylopyranosyl-
• β-D-Glucopyranoside, (3β,12β)-3-[(2-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-20-yl 6-O-β-D-xylopyranosyl-
• Dammarane, β-D-glucopyranoside deriv.
• (3β,12β)-3-[(2-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-20-yl 6-O-β-D-xylopyranosyl-β-D-glucopyranoside
• Ginsenoside Rb3
• β-D-Glucopyranoside, (3β,12β)-3-[(2-O-β-D-
• NH25835
• Ginsenoside Rb3 ,98%
• [3β-[[2-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyl]oxy]-12β-hydroxy-5α-dammar-24-en-20-yl]6-O-(β-D-xylopyranosyl)-β-D-glucopyranoside
• glucopyranosyl)oxy)-12-hydroxydammar-24-en-20-yl6-o-beta-d-xylopyranosyl-
• xylopyranosyl-
• (3-beta,12-beta)-3-((2-o-beta-d-glucopyranosyl-beta-d-alpha-d-glucopyranosid
• Ginsenoside Rb3, 98%, from Panax ginseng C. A. Mey.
• GINSENOSIDE Rb3(SH)
• (2S,3R,4S,5S,6R)-2-[[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-[[(10R,12S,14R)-12-hydroxy-4,4,10,14-tetramethyl-17-[(E,2R)-6-methyl-2-[[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4S,5R)-3,4
• hydroxydammar-24-en-20-yl6-O-β-D-

Ginsenoside Rb3

CAS: 68406-26-8

Ginsenoside Rb3 analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₅₃H₉₀O₂₂

Pureza: (HPLC) ≥97%

Forma y color: Powder

Peso molecular: 1079.29

Ref: 11-0151S

Ginsenoside Rb3

CAS: 68406-26-8

Fórmula: C₅₃H₉₀O₂₂

Pureza: ≥ 98.0%

Forma y color: White to off-white crystalline powder

Peso molecular: 1079.27

Ref: 7W-GC9541

Ginsenoside Rb3

CAS: 68406-26-8

Ginsenoside Rb3 has anti-myocardial ischemia-reperfusion injury, neuroprotective, antidepressant-like, and antioxidant effects, it also possesses the potential of the clinical use in preventing and treating diabetes. Ginsenoside Rb3 significantly attenuates the changes of creatine kinase activity and lactate dehydrogenase activity, exhibits inhibitory effect on TNFα-induced NF-κB transcriptional activity with an IC50 of 8.2 μM in 293T cell lines, it also inhibits the induction of COX-2 and iNOS mRNA.

Fórmula: C₅₃H₉₀O₂₂

Pureza: 95%~99%

Peso molecular: 1079.28

Ref: BP-BP0659

Ginsenoside Rb3

CAS: 68406-26-8

Fórmula: C₅₃H₉₀O₂₂

Peso molecular: 1079.28

Ref: 4Z-G-157024

Ginsenoside Rb3

CAS: 68406-26-8

Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity.

Fórmula: C₅₃H₉₀O₂₂

Pureza: 98% - 99.98%

Forma y color: Solid

Peso molecular: 1079.27

Ref: TM-T3918

Ginsenoside rb3

CAS: 68406-26-8

Natural glycoside

Fórmula: C₅₃H₉₀O₂₂

Pureza: ≥ 90.0 % (HPLC)

Forma y color: Powder

Peso molecular: 1079.29

Ref: 5G-89679

Ginsenoside Rb3

Producto controlado

CAS: 68406-26-8

Stability Hygroscopic
Applications Ginsenoside Rb3 inhibits the upregulation of phospho-IκB-α and nuclear translocation of NF-κB subunit p65 induced by glucose deprivation then reperfusion.
References Ma, L., et. al.: PloS One, 9, e103628/1-e103628/12 (2014)

Fórmula: C₅₃H₉₀O₂₂

Forma y color: Neat

Peso molecular: 1079.27

Ref: TR-G387610

Ginsenoside Rb3

CAS: 68406-26-8

Ginsenoside Rb3 is a natural saponin compound, which is a type of ginsenoside derived from the root of Panax ginseng. The source of Ginsenoside Rb3, Panax ginseng, is a perennial plant widely utilized in traditional medicine for its pharmacological properties.

Fórmula: C₅₃H₉₀O₂₂

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 1,079.27 g/mol

Ref: 3D-OG09286