CAS 6882-68-4

(-)-Soforidina

Descripción:

(-)-Soforidina es un alcaloide derivado de las especies de Sophora, particularmente notable por su presencia en Sophora flavescens. Se caracteriza por su naturaleza quiral, existiendo como un enantiómero específico con actividad biológica. El compuesto típicamente exhibe una apariencia cristalina blanca a blanco sucio y es soluble en disolventes orgánicos, aunque su solubilidad en agua es limitada. (-)-Soforidina ha despertado interés en farmacología debido a sus posibles efectos terapéuticos, incluyendo propiedades antiinflamatorias y neuroprotectoras. Su estructura molecular presenta una disposición compleja de átomos de carbono, hidrógeno, nitrógeno y oxígeno, lo que contribuye a su actividad biológica. El mecanismo de acción del compuesto y las interacciones específicas dentro de los sistemas biológicos son temas de investigación en curso, destacando sus posibles aplicaciones en medicina. Al igual que muchos alcaloides, (-)-Soforidina también puede exhibir toxicidad a ciertas concentraciones, lo que requiere un manejo cuidadoso y consideraciones de dosificación en contextos de investigación y terapéuticos.

Fórmula: C₁₅H₂₄N₂O

InChI: InChI=1/C15H24N2O/c18-14-7-1-6-13-12-5-3-9-16-8-2-4-11(15(12)16)10-17(13)14/h11-13,15H,1-10H2/t11-,12-,13-,15+/m1/s1

Clave InChI: InChIKey=ZSBXGIUJOOQZMP-BHPKHCPMSA-N

SMILES: O=C1N2[C@@]([C@@]3([C@@]4([C@@](C2)(CCCN4CCC3)[H])[H])[H])(CCC1)[H]

Sinónimos:

• (7aR,13aR,13bR,13cS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one
• 1H,5H,10H-Dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one, dodecahydro-, (7aR,13aR,13bR,13cS)-
• 1H,5H,10H-Dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one, dodecahydro-, [7aR-(7aα,13aα,13bβ,13cβ)]-
• 5-Epidihydrosophocarpine
• Allomatrine
• Dihydro-5-episophocarpine
• Matridin-15-one, (5β)-
• Sophoridin
• l-Sophoridine
• Sophoridine
• (5-beta)-matridin-15-on
• Sordidness
• Sophoridine Powder
• (5-beta)-Matridin-15-one
• (7aR,13aR,13bR,13cS)-Dodecahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one
• Matridin-15-one, (5-beta)- (9ci)
• (41S,7aR,13aR,13bR)-Dodecahydro-1H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10(41H)-one
• I-SOPHORIDINE
• OPHORIDINE
• SOLSTITIALIN A 13-ACETATE(SH)(CALL)
• (5β)-Matridin-15-one
• Sophoridine, 98%, from Sophora alopecuroides L.
• 1H,5H,10H-Dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one, dodecahydro-, (7aR,13aR,13bR,13cS)-
• Docusate Sodium Impurity 10

Sophoridine

CAS: 6882-68-4

Fórmula: C₁₅H₂₄N₂O

Pureza: 96%

Forma y color: Solid

Peso molecular: 248.3639

Ref: IN-DA00FA4S

Sophoridin

CAS: 6882-68-4

Sophoridin

Pureza: 98%

Peso molecular: 248.36g/mol

Ref: 54-OR1029187

Sophoridine

CAS: 6882-68-4

Sophoridine

Pureza: ≥95%

Peso molecular: 248.36g/mol

Ref: 54-BUP00156

Sophoridine

CAS: 6882-68-4

Fórmula: C₁₅H₂₄N₂O

Peso molecular: 248.37

Ref: 7W-GY8337

Sophoridine

CAS: 6882-68-4

Fórmula: C₁₅H₂₄N₂O

Pureza: >98.0%(GC)(T)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 248.37

Ref: 3B-M3093

Sophoridine

CAS: 6882-68-4

Sophoridine has anti-inflammatory, anti-cancer and anti-arrhythmia, and affects the immune and central nervous systems. Early and short-time applying sophoridine has neuroprotective effect min permanent middle cerebral artery occlusion (pMCAO) rat brain by down-regulating TRAF6 and up-regulating p-ERK1/2 expression, ameliorating brain infaction and edema. Sophoridine also possesses antiviral activities against Coxsackievirus B3, by regulating cytokine expression, may represent a potential therapeutic agent for viral myocarditis.

Fórmula: C₁₅H₂₄N₂O

Pureza: 95%~99%

Peso molecular: 248.37

Ref: BP-BP1327

Sophoridine

CAS: 6882-68-4

Sophoridine, a natural Chinese anticancer drug, has a potent derivative 6b targeting DNA topoisomerase I in tumor cells, inducing apoptosis.

Fórmula: C₁₅H₂₄N₂O

Pureza: 97.33% - 99.28%

Forma y color: Solid

Peso molecular: 248.36

Ref: TM-T3339

Sophoridine

CAS: 6882-68-4

Natural alkaloid

Fórmula: C₁₅H₂₄N₂O

Pureza: ≥ 90.0 % (HPLC)

Forma y color: Crystalline

Peso molecular: 248.36

Ref: 5G-80540

(-)Sophoridine

Producto controlado

CAS: 6882-68-4

Applications (-)Sophoridine is an anticancer agent, with a promising anti-rumor effect and lower toxicity. Anti-inflammatory.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Liu, H. et al.: J. Chin. Chem. Soc., 61, 897 (2014); Huang, X. et al.: J. Anal. Meth. Chem., 502626, 7 (2014);

Fórmula: C₁₅H₂₄N₂O

Forma y color: Off White Solid

Peso molecular: 248.36

Ref: TR-S676840

Sophoridine

CAS: 6882-68-4

Sophoridine is a quinolizidine alkaloid from Chinese medicinal plant Sophora flavescens. The compound has anti-proliferative effects and inhibits growth of colorectal cancer cells and xenograft tumors. The compound is also a low potency blocker of hERG channel and is able to alter its activation properties. It has antiviral properties against Coxsackievirus B3, which is a causative agent of the viral myocarditis.

Fórmula: C₁₅H₂₄N₂O

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 248.36 g/mol

Ref: 3D-FS65812

Sophoridine

CAS: 6882-68-4

Fórmula: C₁₅H₂₄N₂O

Pureza: ≥98%(GC)(T)

Peso molecular: 248.37

Ref: 10-F053776