CAS 696-04-8

Dihidrotiamina

Descripción:

Dihidrotiamina, con el número CAS 696-04-8, es un derivado de pirimidina y una forma reducida de la timina, una de las cuatro nucleobases en el ADN. Se caracteriza por la presencia de dos átomos de hidrógeno adicionales, lo que resulta en una estructura saturada en comparación con la naturaleza insaturada de la timina. Dihidrotiamina es típicamente un sólido cristalino blanco a blanco sucio, y es soluble en disolventes polares como agua y alcoholes. El compuesto es de interés en la investigación bioquímica, particularmente en estudios relacionados con la reparación del ADN y los efectos del estrés oxidativo en las nucleobases. Su estructura reducida puede influir en la estabilidad y reactividad de los ácidos nucleicos, lo que lo convierte en un tema relevante en los campos de la biología molecular y la química medicinal. Además, Dihidrotiamina puede servir como un compuesto modelo para comprender los mecanismos de daño y reparación del ADN, así como el desarrollo de agentes terapéuticos que apunten a las interacciones de los ácidos nucleicos.

Fórmula: C₅H₈N₂O₂

InChI: InChI=1S/C5H8N2O2/c1-3-2-6-5(9)7-4(3)8/h3H,2H2,1H3,(H2,6,7,8,9)

Clave InChI: InChIKey=NBAKTGXDIBVZOO-UHFFFAOYSA-N

SMILES: O=C1C(C)CNC(=O)N1

Sinónimos:

• (5R)-5-methyldihydropyrimidine-2,4(1H,3H)-dione
• (5S)-5-methyldihydropyrimidine-2,4(1H,3H)-dione
• 2,4(1H,3H)-Pyrimidinedione, dihydro-5-methyl-
• 2-Hydroxy-5-methyl-5,6-dihydro-1H-pyrimidin-4-one
• 5,6-Dihydro-5-methyluracil
• 5,6-Dihydrothymine
• 5-Methyl-5,6-dihydrouracil
• 5-methyldihydropyrimidine-2,4(1H,3H)-dione
• Dihydro-5-methyl-2,4(1H,3H)-pyrimidinedione
• Dihydrothymine
• Hydrouracil, 5-methyl-

5,6-Dihydro-5-methyluracil, 98+%

CAS: 696-04-8

5,6-Dihydro-5-methyluracil, is used as an active pharmaceutical ingredient. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or S

Fórmula: C₅H₈N₂O₂

Pureza: 98+%

Forma y color: Crystals or crystalline powder, White to pale cream

Peso molecular: 128.13

Ref: 02-L01996

5,6-Dihydro-5-methyluracil

CAS: 696-04-8

Fórmula: C₅H₈N₂O₂

Pureza: 97%

Forma y color: Solid

Peso molecular: 128.1292

Ref: IN-DA003MA0

5,6-Dihydro-5-methyluracil

CAS: 696-04-8

5,6-Dihydro-5-methyluracil (Dihydrothymine) is an intermediate breakdown product of thymine.

Fórmula: C₅H₈N₂O₂

Pureza: 98.53%

Forma y color: Solid

Peso molecular: 128.13

Ref: TM-T0532

5,6-Dihydro-5-methyluracil

CAS: 696-04-8

5,6-Dihydro-5-methyluracil

Pureza: ≥98%

Peso molecular: 128.13g/mol

Ref: 54-BUP14147

5,6-Dihydro-5-methyluracil

CAS: 696-04-8

5,6-Dihydro-5-methyluracil

Pureza: 97%

Peso molecular: 128.13g/mol

Ref: 54-OR1026137

5,6-Dihydrothymine-α,alphaalpha,5,6,6-d6 -6

CAS: 334473-42-6, 696-04-8

Pureza: 99 atom % D

Peso molecular: 134.17

Ref: 3U-D7687

5,6-Dihydro Thymine

Producto controlado

CAS: 696-04-8

Applications 5,6-Dihydrothymine is a derivative of Thymine, a nucleobase in the nucleic acid of DNA . 5,6-Dihydrothymine is a radiolysis product of DNA.
References Hubbard, K. et al.: Biochemistry, 28, 4382 (1989); Cadet, J. et al.: Int. J. Rad. Biol. Rel. Stud. Phys. Chem. Med., 39, 119 (1981);

Fórmula: C₅H₈N₂O₂

Forma y color: Neat

Peso molecular: 128.13

Ref: TR-D449440

5-Methyl-dihydro-pyrimidine-2,4-dione

CAS: 696-04-8

Fórmula: C₅H₈N₂O₂

Pureza: 97%

Forma y color: Solid

Peso molecular: 128.131

Ref: 10-F487619

5,6-Dihydro Thymine

CAS: 696-04-8

5,6-Dihydrothymine is a metabolic precursor to thymine. It has been shown to inhibit the production of DNA and RNA in cells, which causes cellular transformation. 5,6-Dihydrothymine also inhibits enzyme activity by competing with substrates or by forming covalent bonds with the enzyme. This drug has been found to be genotoxic and may cause cancer, but it can also be used for diagnosis and treatment of radiation-induced genetic damage. The drug is an oral prodrug that is hydrolyzed in the gastrointestinal tract to release thymine. 5,6-Dihydrothymine is used for molecular pathogenesis studies on solid tumours, such as breast cancer and prostate cancer.

Fórmula: C₅H₈N₂O₂

Pureza: Min. 95%

Peso molecular: 128.13 g/mol

Ref: 3D-AAA69604