CAS 6992-70-7

(1S)-1-C-[(2S,3S)-7-[[4-O-Acetil-2,6-didesoxi-3-O-(2,6-didesoxi-4-O-metil-α-D-lixo-hexopiranosil)-β-D-lixo-hexopiranosil]oxi]-3-[[O-2,6-didesoxi-3-C-metil-4-O-(2-metil-1-oxopropil)-α-L-arabino-hexopiranosil(1→3)-O-2,6-didesoxi-β-D-arabino-hexopiranosil-(1→3)-2,6-didesoxi-β-D-arabino-hexopiranosil]oxi]-1,2,3,4-tetrahidro-5,10-dihidroxi-6-metil-4-oxo-2-antracenil]-5-desoxi-1-O-metil-D-treo-2-pentulosa

Descripción:

La sustancia química con el nombre "(1S)-1-C-[(2S,3S)-7-[[4-O-Acetil-2,6-didesoxi-3-O-(2,6-didesoxi-4-O-metil-α-D-lixo-hexopiranosil)-β-D-lixo-hexopiranosil]oxi]-3-[[O-2,6-didesoxi-3-C-metil-4-O-(2-metil-1-oxopropil)-α-L-arabino-hexopiranosil(1→3)-O-2,6-didesoxi-β-D-arabino-hexopiranosil-(1→3)-2,6-didesoxi-β-D-arabino-hexopiranosil]oxi]-1,2,3,4-tetrahidro-5,10-dihidroxi-6-metil-4-oxo-2-antracenil]-5-desoxi-1-O-metil-D-treo-2-pentulosa" y el número CAS "6992-70-7" es un compuesto orgánico complejo caracterizado por su estructura intrincada, que incluye múltiples moieties de azúcar y un núcleo de antraceno. Este compuesto exhibe propiedades típicas de los glucósidos, como la solubilidad en solventes polares y la posible actividad biológica debido a sus componentes de azúcar. La presencia de varios grupos funcionales, incluidos grupos hidroxilo, acetilo y metilo, sugiere que puede participar en enlaces de hidrógeno y otras interacciones intermoleculares, influyendo en su reactividad y estabilidad. Su estereoquímica, indicada por las configuraciones específicas en varios centros quirales, es crucial para su función biológica e interacción con enzimas o receptores. En general, la complejidad y diversidad estructural de este compuesto lo convierten en un tema de interés en campos como la química medicinal y la bioquímica.

Fórmula: C₅₉H₈₆O₂₆

InChI: InChI=1S/C59H86O26/c1-22(2)58(70)85-57-29(9)78-43(21-59(57,11)71)82-37-18-40(74-25(5)49(37)66)81-36-19-42(75-26(6)48(36)65)84-56-33(55(73-13)52(69)47(64)24(4)60)15-31-14-32-16-35(23(3)46(63)44(32)50(67)45(31)51(56)68)80-41-20-38(54(28(8)77-41)79-30(10)61)83-39-17-34(62)53(72-12)27(7)76-39/h14,16,22,24-29,33-34,36-43,47-49,53-57,60,62-67,71H,15,17-21H2,1-13H3/t24-,25-,26-,27-,28-,29+,33+,34-,36-,37-,38-,39-,40+,41+,42+,43+,47+,48-,49-,53+,54+,55+,56+,57+,59+/m1/s1

Clave InChI: InChIKey=WPLCTUHONLQGIX-TWTCTLMISA-N

SMILES: O=C1C=2C(C[C@@]([C@@H](C([C@H]([C@@H](C)O)O)=O)OC)([C@@H]1O[C@H]3C[C@@H](O[C@H]4C[C@@H](O[C@H]5C[C@](C)(O)[C@@H](OC(C(C)C)=O)[C@H](C)O5)[C@H](O)[C@@H](C)O4)[C@H](O)[C@@H](C)O3)[H])=CC=6C(C2O)=C(O)C(C)=C(O[C@H]7C[C@@H](O[C@@H]8C[C@@H](O)[C@@H](OC)[C@@H](C)O8)[C@@H](OC(C)=O)[C@@H](C)O7)C6

Sinónimos:

• (1S)-1-C-[(2S,3S)-7-[[4-O-Acetyl-2,6-dideoxy-3-O-(2,6-dideoxy-4-O-methyl-α-<span class="text-smallcaps">D</smallcap>-lyxo-hexopyranosyl)-β-<smallcap>D</smallcap>-lyxo-hexopyranosyl]oxy]-3-[[O-2,6-dideoxy-3-C-methyl-4-O-(2-methyl-1-oxopropyl)-α-<smallcap>L</smallcap>-arabino-hexopyranosyl(1→3)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-arabino-hexopyranosyl-(1→3)-2,6-dideoxy-β-<smallcap>D</smallcap>-arabino-hexopyranosyl]oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-5-deoxy-1-O-methyl-<smallcap>D</span>-threo-2-pentulose
• (1S)-1-C-[(2S,3S)-7-{[4-O-acetyl-2,6-dideoxy-3-O-(2,6-dideoxy-4-O-methyl-alpha-D-lyxo-hexopyranosyl)-beta-D-lyxo-hexopyranosyl]oxy}-3-{[2,6-dideoxy-3-C-methyl-4-O-(2-methylpropanoyl)-alpha-L-arabino-hexopyranosyl-(1->3)-2,6-dideoxy-beta-D-arabino-hexopyranosyl-(1->3)-2,6-dideoxy-beta-D-arabino-hexopyranosyl]oxy}-5,10-dihydroxy-6-methyl-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl]-5-deoxy-1-O-methyl-D-xylulose
• 1-C-(7-{[4-O-acetyl-2,6-dideoxy-3-O-(2,6-dideoxy-4-O-methylhexopyranosyl)hexopyranosyl]oxy}-3-{[2,6-dideoxy-3-C-methyl-4-O-(2-methylpropanoyl)hexopyranosyl-(1->3)-2,6-dideoxyhexopyranosyl-(1->3)-2,6-dideoxyhexopyranosyl]oxy}-4,10-dihydroxy-6-methyl-5-oxo-
• <span class="text-smallcaps">D</smallcap>-threo-2-Pentulose, 1-C-[(2S,3S)-7-[[4-O-acetyl-2,6-dideoxy-3-O-(2,6-dideoxy-4-O-methyl-α-<smallcap>D</smallcap>-lyxo-hexopyranosyl)-β-<smallcap>D</smallcap>-lyxo-hexopyranosyl]oxy]-3-[[O-2,6-dideoxy-3-C-methyl-4-O-(2-methyl-1-oxopropyl)-α-<smallcap>L</smallcap>-arabino-hexopyranosyl(1→3)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-arabino-hexopyranosyl-(1→3)-2,6-dideoxy-β-<smallcap>D</span>-arabino-hexopyranosyl]oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-5-deoxy-1-O-methyl-, (1S)-
• Aburamycin A
• Chromomycin A₂
• Chromomycinone, 6-(4-O-α-olivomosyl-β-olioside) 2-(O-α-olivomycosyl-(1→3)-O-β-olivosyl-(1→3)-β-olivoside), acetate isobutyrate
• Chromomycinone, 6-[2,6-dideoxy-4-O-(2,6-dideoxy-4-O-methyl-<span class="text-smallcaps">D</smallcap>-lyxo-hexopyranosyl)-<smallcap>D</smallcap>-lyxo-hexopyranoside] 2-(O-2,6-dideoxy-3-C-methyl-<smallcap>L</smallcap>-arabino-hexopyranosyl-(1→3)-O-2,6-dideoxy-<smallcap>D</smallcap>-arabino-hexopyranosyl-(1→3)-2,6-dideoxy-<smallcap>D</span>-arabino-hexopyranoside), monoacetate monoisobutyrate
• NSC 131187
• Olivomycin D, 3^D-O-[2,6-dideoxy-3-C-methyl-4-O-(2-methyl-1-oxopropyl)-α-<span class="text-smallcaps">L</span>-arabino-hexopyranosyl]-7-methyl-
• Olivomycin D, 3D-O-[2,6-dideoxy-3-C-methyl-4-O-(2-methyl-1-oxopropyl)-α-L-arabino-hexopyranosyl]-7-methyl-
• Chromomycinone, 6-[2,6-dideoxy-4-O-(2,6-dideoxy-4-O-methyl-D-lyxo-hexopyranosyl)-D-lyxo-hexopyranoside] 2-(O-2,6-dideoxy-3-C-methyl-L-arabino-hexopyranosyl-(1→3)-O-2,6-dideoxy-D-arabino-hexopyranosyl-(1→3)-2,6-dideoxy-D-arabino-hexopyranoside), monoacetate monoisobutyrate
• (1S)-1-C-[(2S,3S)-7-[[4-O-Acetyl-2,6-dideoxy-3-O-(2,6-dideoxy-4-O-methyl-α-D-lyxo-hexopyranosyl)-β-D-lyxo-hexopyranosyl]oxy]-3-[[O-2,6-dideoxy-3-C-methyl-4-O-(2-methyl-1-oxopropyl)-α-L-arabino-hexopyranosyl(1→3)-O-2,6-dideoxy-β-D-arabino-hexopyranosyl-(1→3)-2,6-dideoxy-β-D-arabino-hexopyranosyl]oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-5-deoxy-1-O-methyl-D-threo-2-pentulose

Chromomycin A2

CAS: 6992-70-7

Chromomycin A2, from marine actinomycetes, halts B. subtilis and various cancer cells; promotes autophagy in melanoma.

Fórmula: C₅₉H₈₆O₂₆

Forma y color: Solid

Peso molecular: 1211.3

Ref: TM-T36846