CAS 7059-24-7: Cromomicina A3

Descripción: Cromomicina A3 es un antibiótico antraciclínico producido por la bacteria *Streptomyces griseus*. Se conoce principalmente por su uso en el tratamiento del cáncer debido a su capacidad para intercalar el ADN, inhibiendo así la síntesis de ADN y ARN. Este compuesto exhibe un color amarillo brillante y es soluble en agua, lo que facilita su uso en diversas aplicaciones biológicas. Cromomicina A3 tiene una fórmula molecular que refleja su estructura compleja, con múltiples anillos aromáticos y moieties de azúcar, que contribuyen a su actividad biológica. Su mecanismo de acción implica la unión a regiones ricas en GC del ADN, lo que lleva a la interrupción de los procesos celulares en células que se dividen rápidamente, lo que es característico de muchos agentes anticancerígenos. Además, se ha estudiado Cromomicina A3 por su posible uso en biología molecular como una sonda fluorescente para la detección de ADN. Sin embargo, su uso clínico es limitado debido a la posible toxicidad y efectos secundarios, lo que requiere una cuidadosa consideración en las aplicaciones terapéuticas. En general, Cromomicina A3 representa un compuesto significativo en el campo de la química medicinal y la investigación del cáncer.

Fórmula: C₅₇H₈₂O₂₆

InChI: InChI=1S/C57H82O26/c1-21-34(79-40-19-37(53(26(6)75-40)77-28(8)59)82-38-16-33(61)52(70-11)25(5)74-38)15-31-13-30-14-32(54(71-12)51(68)46(63)22(2)58)55(50(67)44(30)49(66)43(31)45(21)62)83-41-18-35(47(64)24(4)73-41)80-39-17-36(48(65)23(3)72-39)81-42-20-57(10,69)56(27(7)76-42)78-29(9)60/h13,15,22-27,32-33,35-42,46-48,52-56,58,61-66,69H,14,16-20H2,1-12H3/t22-,23-,24-,25-,26-,27+,32+,33-,35-,36-,37-,38-,39+,40+,41+,42+,46+,47-,48-,52+,53+,54+,55+,56+,57+/m1/s1

Clave InChI: InChIKey=ZYVSOIYQKUDENJ-WKSBCEQHSA-N

SMILES: O=C(OC1C(OC(OC=2C=C3C=C4C(C(=O)C(OC5OC(C)C(O)C(OC6OC(C)C(O)C(OC7OC(C)C(OC(=O)C)C(O)(C)C7)C6)C5)C(C4)C(OC)C(=O)C(O)C(O)C)=C(O)C3=C(O)C2C)CC1OC8OC(C)C(OC)C(O)C8)C)C

Sinónimos:

• (1S)-1-C-[(2S,3S)-7-[[4-O-Acetyl-2,6-dideoxy-3-O-(2,6-dideoxy-4-O-methyl-α-<span class="text-smallcaps">D</smallcap>-lyxo-hexopyranosyl)-β-<smallcap>D</smallcap>-lyxo-hexopyranosyl]oxy]-3-[[O-4-O-acetyl-2,6-dideoxy-3-C-methyl-α-<smallcap>L</smallcap>-arabino-hexopyranosyl-(1→3)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-arabino-hexopyranosyl-(1→3)-2,6-dideoxy-β-<smallcap>D</smallcap>-arabino-hexopyranosyl]oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-5-deoxy-1-O-methyl-<smallcap>D</span>-threo-2-pentulose
• (1S)-1-C-[(2S,3S)-7-{[4-O-acetyl-2,6-dideoxy-3-O-(2,6-dideoxy-4-O-methyl-alpha-D-lyxo-hexopyranosyl)-beta-D-lyxo-hexopyranosyl]oxy}-3-{[4-O-acetyl-2,6-dideoxy-3-C-methyl-alpha-L-arabino-hexopyranosyl-(1->3)-2,6-dideoxy-beta-D-arabino-hexopyranosyl-(1->3)-2,6-dideoxy-beta-D-arabino-hexopyranosyl]oxy}-5,10-dihydroxy-6-methyl-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl]-5-deoxy-1-O-methyl-D-xylulose
• 3D-O-(4-O-Acetyl-2,6-dideoxy-3-C-methyl-alpha-L-arabino-hexopyranosyl)-7-methylolivomycin D
• <span class="text-smallcaps">D</smallcap>-threo-2-Pentulose, 1-C-[(2S,3S)-7-[[4-O-acetyl-2,6-dideoxy-3-O-(2,6-dideoxy-4-O-methyl-α-<smallcap>D</smallcap>-lyxo-hexopyranosyl)-β-<smallcap>D</smallcap>-lyxo-hexopyranosyl]oxy]-3-[[O-4-O-acetyl-2,6-dideoxy-3-C-methyl-α-<smallcap>L</smallcap>-arabino-hexopyranosyl-(1→3)-O-2,6-dideoxy-β-<smallcap>D</smallcap>-arabino-hexopyranosyl-(1→3)-2,6-dideoxy-β-<smallcap>D</span>-arabino-hexopyranosyl]oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-5-deoxy-1-O-methyl-, (1S)-
• Aburamycin B
• Antibiotic 69895 A
• Antibiotic B 599
• Antibiotic from Streptomyces griseus
• CMA³
• Ccris 2755
• Chromomycin A(sub 3)
• Chromomycin A₃
• Nsc 58514
• Olivomycin D, 3^D-O-(4-O-acetyl-2,6-dideoxy-3-C-methyl-α-<span class="text-smallcaps">L</span>-arabino-hexopyranosyl)-7-methyl-
• Olivomycin D, 3B-O-(4-O-acetyl-2,6-dideoxy-3-C-methyl-alpha-L-arabino-hexopyranosyl)-7-methyl- (9CI)
• Olivomycin D, 3B-O-(4-O-acetyl-2,6-dideoxy-3-C-methyl-alpha-L-arabinohexopyranosyl)-7-methyl-
• Olivomycin D, 3D-O-(4-O-acetyl-2,6-dideoxy-3-C-methyl-alpha-L-arabino-hexopyranosyl)-7-methyl-
• Toyomycin
• (1S)-1-C-[(2S,3S)-7-[[4-O-Acetyl-2,6-dideoxy-3-O-(2,6-dideoxy-4-O-methyl-α-D-lyxo-hexopyranosyl)-β-D-lyxo-hexopyranosyl]oxy]-3-[[O-4-O-acetyl-2,6-dideoxy-3-C-methyl-α-L-arabino-hexopyranosyl-(1→3)-O-2,6-dideoxy-β-D-arabino-hexopyranosyl-(1→3)-2,6-dideoxy-β-D-arabino-hexopyranosyl]oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-5-deoxy-1-O-methyl-D-threo-2-pentulose
• D-threo-2-Pentulose, 1-C-[(2S,3S)-7-[[4-O-acetyl-2,6-dideoxy-3-O-(2,6-dideoxy-4-O-methyl-α-D-lyxo-hexopyranosyl)-β-D-lyxo-hexopyranosyl]oxy]-3-[[O-4-O-acetyl-2,6-dideoxy-3-C-methyl-α-L-arabino-hexopyranosyl-(1→3)-O-2,6-dideoxy-β-D-arabino-hexopyranosyl-(1→3)-2,6-dideoxy-β-D-arabino-hexopyranosyl]oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-5-deoxy-1-O-methyl-, (1S)-
• Chromomycin A3
• Olivomycin D, 3D-O-(4-O-acetyl-2,6-dideoxy-3-C-methyl-α-L-arabino-hexopyranosyl)-7-methyl-

Chromomycin A3, 97%

CAS: 7059-24-7

Chromomycin A3, is used as a G-C specific DNA ligand which inhibits transcription and acts …

• Fórmula: C₅₇H₈₂O₂₆
• Pureza: 97%
• Forma y color: Yellow, Powder or crystals or crystalline powder
• Peso molecular: 1183.26

Chromomycin A3

CAS: 7059-24-7

• Fórmula: C₅₇H₈₂O₂₆
• Pureza: ≥ 99%
• Forma y color: Yellow powder
• Peso molecular: 1183.30

Chromomycin A3

CAS: 7059-24-7

Chromomycin A3: aureolic acid antitumor antibiotic, stains human sperm chromatin, induces autophagy, inhibits apoptosis.

• Fórmula: C₅₇H₈₂O₂₆
• Pureza: 98%
• Forma y color: Solid
• Peso molecular: 1183.25

Chromomycin A3

CAS: 7059-24-7

• Fórmula: C₅₇H₈₂O₂₆
• Pureza: By hplc: 99.39% (Typical Value in Batch COA)
• Forma y color: yellow powder
• Peso molecular: 1,183.25g/mol

Chromomycin A3 from streptomyces griseus

CAS: 7059-24-7

Please enquire for more information about Chromomycin A3 from streptomyces griseus including the price, delivery …

• Fórmula: C₅₇H₈₂O₂₆
• Pureza: Min. 95 Area-%
• Forma y color: Powder
• Peso molecular: 1,183.25 g/mol