CAS 71-27-2

Cloruro de succinilcolina

Descripción:

Cloruro de succinilcolina es un bloqueador neuromuscular sintético y despolarizante comúnmente utilizado en entornos médicos, particularmente para facilitar la intubación y proporcionar relajación muscular durante procedimientos quirúrgicos. Es un compuesto de amonio cuaternario derivado de la combinación de dos moléculas de acetilcolina, lo que conduce a su acción en la unión neuromuscular. La sustancia se caracteriza por su inicio rápido y corta duración de acción, que típicamente dura solo unos minutos, lo que la hace ideal para intervenciones quirúrgicas cortas. La succinilcolina actúa uniéndose a los receptores nicotínicos de acetilcolina en la placa terminal motora, causando una contracción muscular inicial seguida de parálisis debido a la despolarización sostenida. Es importante señalar que su uso puede estar asociado con efectos secundarios, incluyendo hiperkalemia, hipertermia maligna y bradicardia. Debido a sus propiedades farmacológicas, la succinilcolina se clasifica como una sustancia controlada de la Lista IV en algunas jurisdicciones, y su administración debe ser cuidadosamente monitoreada por profesionales de la salud.

Fórmula: C₁₄H₃₀N₂O₄·2Cl

InChI: InChI=1S/C14H30N2O4.2ClH/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2

Clave InChI: InChIKey=YOEWQQVKRJEPAE-UHFFFAOYSA-L

SMILES: C([N+](C)(C)C)COC(CCC(OCC[N+](C)(C)C)=O)=O.[Cl-]

Sinónimos:

• (2-Hydroxyethyl)trimethylammonium chloride succinate
• 2,2-Succinyldioxybis(Ethyltrimethylammonium) Dichloride
• 2-Dimethylaminoethyl succinate dimethochloride
• Anectine
• Anectine chloride
• Bis(2-dimethylaminoethyl) succinate bis(methochloride)
• Choline succinate dichloride
• Choline, chloride, succinate (2:1)
• Choline,chloride succinate
• Diacetylcholine dichloride
• Ethanaminium, 2,2′-[(1,4-dioxo-1,4-butanediyl)bis(oxy)]bis[N,N,N-trimethyl-, chloride (1:2)
• Ethanaminium, 2,2′-[(1,4-dioxo-1,4-butanediyl)bis(oxy)]bis[N,N,N-trimethyl-, dichloride
• Lysthenon
• Lysthenone
• Midarine
• Myoplegine
• Pantolax
• Quelicin
• Quelicin chloride
• Querlicin
• Scoline
• Scoline chloride
• Skolin
• Succicuran
• Succin
• Succinic acid bis[β-dimethylaminoethyl] ester dimethochloride
• Succinic acid, diester with choline chloride
• Succinolin
• Succinoylcholine chloride
• Succinyl bischoline chloride
• Succinyl-asta
• Succinylbischoline dichloride
• Succinylcholine chloride
• Succinylcholine dichloride
• Succinyldicholine chloride
• Succinylforte
• Sucostrin
• Sucostrin chloride
• Sukolin

Succinylcholine Chloride Dihydrate

CAS: 6101-15-1, 71-27-2

Fórmula: C₁₄H₃₀Cl₂N₂O₄·2H₂O

Pureza: >98.0%(T)

Forma y color: White to Almost white powder to crystal

Peso molecular: 397.33

Ref: 3B-S0149

Succinylcholine Chloride

CAS: 71-27-2

Fórmula: C₁₄H₃₀N₂O₄·2Cl

Peso molecular: 290.40 2 35.45

Ref: 4Z-C-5916

Succinylcholine Chloride

Producto controlado

CAS: 71-27-2

Stability Hygroscopic
Applications A neuromuscular blocking agent. Muscle relaxant (skeletal).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Jensen, B., et al.: Acta Chem. Scand., 30, 1002 (1976), Anttila, P., et al.: Med. Biol., 56, 152 (1978), Foss, P.R.B., et al.: Anal. Profiles Drug Subs., 10, 691 (1981),

Fórmula: C₁₄H₃₀N₂O₄·2Cl

Forma y color: Neat

Peso molecular: 361.30

Ref: TR-S692100

Succinylcholine Chloride-13C6

Producto controlado

CAS: 71-27-2

Applications A neuromuscular blocking agent. Muscle relaxant (skeletal).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Jensen, B., et al.: Acta Chem. Scand., 30, 1002 (1976), Anttila, P., et al.: Med. Biol., 56, 152 (1978), Foss, P.R.B., et al.: Anal. Profiles Drug Subs., 10, 691 (1981),

Fórmula: C₆C₈H₃₀N₂O₄·2Cl

Forma y color: Neat

Peso molecular: 367.261

Ref: TR-S692102

Succinylcholine chloride

CAS: 71-27-2

Succinylcholine chloride is a muscle relaxant that has been used to treat herpes simplex virus, congenital heart disease, and other conditions. Succinylcholine chloride is an ester of succinic acid and choline. It binds to the acetylcholine receptor on the postsynaptic membrane of skeletal muscles, which leads to depolarization and contraction. The binding of succinylcholine to its receptor triggers an influx of sodium ions into the cell, which causes membrane depolarization and muscle relaxation. Succinylcholine chloride has been shown to have neurotrophic effects in a study where it was administered to mice with experimental myocardial infarction. This drug also has been shown to increase microvessel density in pigs with intubation.

Fórmula: C₁₄H₃₀Cl₂N₂O₄

Pureza: (Hplc) Min. 96%

Forma y color: Powder

Peso molecular: 361.3 g/mol

Ref: 3D-FS27921