CAS 71989-31-6

Fmoc-Pro-OH

Descripción:

Fmoc-Pro-OH, o 9-fluorenilmetoxicarbonilo-prolina, es un aminoácido protegido comúnmente utilizado en la síntesis de péptidos. Presenta un grupo fluorenilmetoxicarbonilo (Fmoc), que actúa como un grupo protector para la funcionalidad amino de la prolina, permitiendo reacciones selectivas durante el ensamblaje de péptidos. El grupo Fmoc es estable en condiciones básicas, pero puede ser eliminado en condiciones ácidas suaves, facilitando el paso de desprotección en la síntesis de péptidos. Fmoc-Pro-OH se caracteriza por su relativamente alta solubilidad en disolventes orgánicos, como el dimetilformamida (DMF) y el diclorometano, mientras que es menos soluble en agua. Este compuesto es crucial en la síntesis de péptidos en fase sólida, donde ayuda en la adición secuencial de aminoácidos para formar péptidos. Su estructura incluye un esqueleto de prolina, que introduce propiedades conformacionales únicas debido a su estructura cíclica, influyendo en la estructura secundaria general del péptido. El número CAS 71989-31-6 identifica de manera única este compuesto, asegurando una comunicación precisa en la literatura científica y bases de datos.

Fórmula: C₂₀H₁₉NO₄

InChI: InChI=1S/C20H19NO4/c22-19(23)18-10-5-11-21(18)20(24)25-12-17-15-8-3-1-6-13(15)14-7-2-4-9-16(14)17/h1-4,6-9,17-18H,5,10-12H2,(H,22,23)/t18-/m0/s1

Clave InChI: InChIKey=ZPGDWQNBZYOZTI-SFHVURJKSA-N

SMILES: C(OC(=O)N1[C@H](C(O)=O)CCC1)C2C=3C(C=4C2=CC=CC4)=CC=CC3

Sinónimos:

• (2S)-1-[(9H-Fluoren-9-ylmethoxy)carbonyl]pyrrolidine-2-carboxylic acid
• (2S)-1-[[(9H-Fluoren-9-yl)methoxy]carbonyl]pyrrolidine-2-carboxylic acid
• (S)-N-(9-Fluorenylmethoxycarbonyl)proline
• (S)-hidrogenopirrolidina-1,2-dicarboxilato de 1-(9H-fluoren-9-ilmetilo)
• (S)-hydrogenopyrrolidine-1,2-dicarboxylate de 1-(9H-fluorene-9-ylmethyle)
• 1,2-Pyrrolidinedicarboxylic acid, 1-(9H-fluoren-9-ylmethyl) ester, (S)-
• 1-(9H-fluoren-9-ylmethyl) hydrogen (S)-pyrrolidine-1,2-dicarboxylate
• 1-(9H-fluoren-9-ylmethyl)-(S)-hydrogenpyrrolidin-1,2-dicarboxylat
• Fluorenylmethoxycarbonylproline
• Fmoc-<span class="text-smallcaps">L</span>-Pro-OH
• Fmoc-<span class="text-smallcaps">L</span>-proline
• Fmoc-L-proline
• Fmoc-Pro-OH
• N-(9-Fluorenylmethoxycarbonyl)-<span class="text-smallcaps">L</span>-proline
• N-(9-Fluorenylmethoxycarbonyl)-L-proline
• N-(9-Fluorenylmethoxycarbonyl)proline
• N-FMOC-<span class="text-smallcaps">L</span>-proline
• N-FMOC-L-proline
• Nsc 334294

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-proline

CAS: 71989-31-6

Fórmula: C₂₀H₁₉NO₄

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 337.38

Ref: 3B-F0298

N-Fmoc-L-proline, 98%

CAS: 71989-31-6

It is used as pharmaceutical intermediate. Fmoc method is used for the synthesis of the new polymeric support for the preparation of C-terminal peptide amides. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label inform

Fórmula: C₂₀H₁₉NO₄

Pureza: 98%

Forma y color: Crystals or powder or crystalline powder, White to pale cream

Peso molecular: 337.38

Ref: 02-B21081

Fmoc-Pro-OH

CAS: 71989-31-6

M03372 - Fmoc-Pro-OH

Fórmula: C₂₀H₁₉NO₄

Pureza: 98%

Forma y color: Solid, Crystalline or Powder

Peso molecular: 337.375

Ref: 10-M03372

Fmoc-Pro-OH

CAS: 71989-31-6

Bachem ID: 4003150.

Fórmula: C₂₀H₁₉NO₄

Pureza: 99.8%

Forma y color: White

Peso molecular: 337.38

Ref: 01-4003150

Fmoc-Pro-OH

CAS: 71989-31-6

Fórmula: C₂₀H₁₉NO₄

Pureza: 98%

Forma y color: Solid

Peso molecular: 337.3692

Ref: IN-DA003QO0

Fmoc-L-Proline

CAS: 71989-31-6

Fmoc-L-Proline (Fmoc-Pro-OH) is a proline derivative.

Fórmula: C₂₀H₁₉NO₄

Pureza: 99.22%

Forma y color: Solid

Peso molecular: 337.37

Ref: TM-T64331

Fmoc-L-Proline, 10mM (in DMSO)

CAS: 71989-31-6

Fmoc-L-Proline, 10mM (in DMSO)

Pureza: ≥98%

Peso molecular: 337.37g/mol

Ref: 54-BUP19106

Fmoc-Pro-OH

CAS: 71989-31-6

Fórmula: C₂₀H₁₉NO₄

Pureza: ≥ 99.0%

Forma y color: White to off-white or pale yellow crystalline powder

Peso molecular: 337.38

Ref: 7W-GM2265

FMOC-Pro-OH

CAS: 71989-31-6

FMOC-Pro-OH

Fórmula: C₂₀H₁₉NO₄

Pureza: 98%

Forma y color: white to off white powder

Peso molecular: 337.37g/mol

Ref: 54-OR54567

L-Proline-2,5,5-d3-N-FMOC

CAS: 71989-31-6

Pureza: 98 atom % D

Forma y color: White Solid

Peso molecular: 340.39

Ref: 3U-D7565

Fmoc-Pro-OH

CAS: 71989-31-6

Fórmula: C₂₀H₁₉NO₄

Peso molecular: 337.38

Ref: 4Z-P-166009

Fmoc-Pro-OH

CAS: 71989-31-6

Fmoc-Pro-OH is a synthetic cyclic peptide with the amino acid sequence (Fmoc-Lys-Lys-Ala-Glu)n. Fmoc-Pro-OH binds to the androgen receptor and can be used as a research tool to identify other molecules that bind to the same receptor. It has been shown to inhibit the activity of ester hydrochloride, trifluoroacetic acid, and superparamagnetic iron in coordination complexes.

Fórmula: C₂₀H₁₉NO₄

Pureza: Min. 95 Area-%

Forma y color: White Off-White Powder

Peso molecular: 337.37 g/mol

Ref: 3D-FF15871

Fmoc-Pro-OH

CAS: 71989-31-6

Fmoc-Pro-OH is a peptide that contains the Fmoc protecting group. It is used in the synthesis of peptides and has been shown to be effective against microbial infections with marine sponges. The synthesis of this compound can be carried out on an on-line automated peptide synthesizer. The Fmoc protecting group is removed by treatment with trifluoroacetic acid (TFA) in dichloromethane, which leaves the side chain unprotected. This compound has a high binding affinity for the receptor site of fibrinogen and can potentially inhibit the growth of bacteria that cause bacterial infection, such as Staphylococcus aureus and Pseudomonas aeruginosa.
Fmoc-Pro-OH can also be used to synthesize other functional groups such as sulfamoyl groups or acetonitrile groups, depending on the desired outcome.

Fórmula: C₂₀H₁₉NO₄

Pureza: Min. 98 Area-%

Peso molecular: 337.38 g/mol

Ref: 3D-FLP-1731-PI

FMOC-L-Proline extrapure, 99%

CAS: 71989-31-6

Fórmula: C₂₀H₁₉NO₄

Pureza: min. 99%

Forma y color: White to Off white, Crystalline powder

Peso molecular: 337.38

Ref: SR-12047

L-Proline-N-Fmoc

Producto controlado

CAS: 71989-31-6

Applications L-Proline-N-Fmoc is N-Fmoc protected L-Proline (P755995) which is an amino acid and precursor (with vitamin C) for collagen, the building block of the structure of tendons, ligaments, arteries, veins and muscles. It is important in wound healing.
References Bondarenko, L.B., et al.: Int. J. Peptides., 2, 1687 (2012); Rimer, T., et al.: Biomacromolecules, 13, 2110 (2012);

Fórmula: C₂₀H₁₉NO₄

Forma y color: Neat

Peso molecular: 337.37

Ref: TR-P756005

L-Proline-d3-N-Fmoc

Producto controlado

CAS: 71989-31-6

Applications L-Proline-d3-N-Fmoc was used to prepare potent bombesin-like peptides for GRP-receptor targeting of tumors. It was also used to synthesize tetrapeptide aldehyde inhibitors of dengue virus NS3 protease.
References Nock, B., et al.: J. Med. Chem., 48, 100 (2005); Yin, Z., et al.: Bioorg. Med. Chem. Lett., 16, 40 (2006)

Fórmula: C₂₀D₃H₁₆NO₄

Forma y color: Neat

Peso molecular: 340.39

Ref: TR-P756007