CAS 71989-35-0

N-(9-Fluorenilmetoxicarbonil)-O-terc-butiltreonina

Descripción:

N-(9-Fluorenilmetoxicarbonil)-O-terc-butiltreonina, comúnmente conocido como Fmoc-O-t-Bu-Thr, es un derivado de aminoácido protegido ampliamente utilizado en la síntesis de péptidos. Este compuesto presenta un grupo 9-fluorenilmetoxicarbonilo (Fmoc), que actúa como un grupo protector para la funcionalidad amino, permitiendo reacciones selectivas durante el ensamblaje de péptidos. El grupo tert-butilo en la cadena lateral de la treonina proporciona impedimento estérico, mejorando la estabilidad de la molécula y facilitando los procesos de purificación. Fmoc-O-t-Bu-Thr se utiliza típicamente en la síntesis de péptidos en fase sólida, donde el grupo Fmoc puede ser fácilmente eliminado en condiciones básicas, permitiendo el acoplamiento subsiguiente de aminoácidos. El compuesto se caracteriza por su estabilidad relativamente alta en condiciones de laboratorio estándar, lo que lo hace adecuado para diversas aplicaciones sintéticas. Su solubilidad en disolventes orgánicos y su solubilidad moderada en agua contribuyen aún más a su utilidad en la química de péptidos. En general, Fmoc-O-t-Bu-Thr es un bloque de construcción esencial en la síntesis de péptidos, particularmente en el contexto del desarrollo de agentes terapéuticos y herramientas de investigación en bioquímica.

Fórmula: C₂₃H₂₇NO₅

InChI: InChI=1/C23H27NO5/c1-14(29-23(2,3)4)20(21(25)26)24-22(27)28-13-19-17-11-7-5-9-15(17)16-10-6-8-12-18(16)19/h5-12,14,19-20H,13H2,1-4H3,(H,24,27)(H,25,26)/p-1/t14-,20+/m1/s1

Clave InChI: InChIKey=LZOLWEQBVPVDPR-VLIAUNLRSA-N

SMILES: C(OC(N[C@@H]([C@H](OC(C)(C)C)C)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Sinónimos:

• (2S,3R)-2-(((9-Fluorenylmethoxy)carbonyl)amino)-3-(tert-butoxy)butanoic acid
• (2S,3R)-3-tert-Butoxy-2-[[[[9H-fluoren-9-yl]methoxy]carbonyl]amino)butanoic acid
• (2S,3R)-3-tert-butoxy-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanoate
• <span class="text-smallcaps">L</span>-Threonine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• FMOC-O-tert-Butyl-L-threonine
• Fmoc-L-Thr(tBu)-OH
• Fmoc-Thr(OtBu)-OH
• N-(9-Fluorenylmethoxycarbonyl)-O-tert-butylthreonine
• O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-threonine
• O-tert-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-threonine
• O-tert-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]threonine
• L-Threonine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-threonine
• N-9-FLUORENYLMETHYLOXYCARBONYL-O-TERT-BUTYL-L-THREONINE
• N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-T-BUTYL-L-THREONINE
• FMOC-L-THR(O-T-BUTYL)
• FMOC-THR(TBU)
• FMOC-THREONINE(TBU)-OH
• FMOC-L-THREONINE (TBU)
• FMOC-L-THREONINE(O-T-BUTYL)
• 9-FLUORENYLMETHOXYCARBONYL-O-T-BUTYL-L-THREONINE
• FMOC-O-T-BUTYL-L-THREONINE
• N-(9-FLUORENYL METHOXY CARBONYL)-O-TERT-BUTYL-L-THREONINE
• FMOC-THR(BUT)
• NALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-TERT-BUTYL-L-THREONINE
• N-(9-FLUORENYLMETHOXYCARBONYL)-O-TERT-BUTYL-L-THRETONINE
• FMOC-THR(TBU)-OH
• N-9-FLUORENYLMETHYLOXYCARBONYL-O-T-BUTYL-L-THREONINE
• FMOC-THR(BUT)-OH
• 9-FLUORENYLMETHOXYCARBONYL-O-T-BUTYL-L-THEONINE

Fmoc-Thr(tBu)-OH

CAS: 71989-35-0

M03389 - Fmoc-Thr(tBu)-OH

Fórmula: C₂₃H₂₇NO₅

Pureza: 97%

Forma y color: Crystalline,Powder

Peso molecular: 397.471

Ref: 10-M03389

Nα-Fmoc-O-tert-butyl-L-threonine, 98%

CAS: 71989-35-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₂₃H₂₇NO₅

Pureza: 98%

Forma y color: White, Powder

Peso molecular: 397.47

Ref: 02-H59808

Fmoc-Thr(tBu)-OH

CAS: 71989-35-0

Bachem ID: 4096755.

Fórmula: C₂₃H₂₇NO₅

Pureza: 99.9%

Forma y color: White

Peso molecular: 397.47

Ref: 01-4096755

(2S,3R)-2-(((9-Fluorenylmethoxy)carbonyl)amino)-3-(tert-butoxy)butanoic acid

CAS: 71989-35-0

Fórmula: C₂₃H₂₇NO₅

Pureza: 98%

Forma y color: Solid

Peso molecular: 397.4642

Ref: IN-DA0034Y8

Fmoc-Thr(tBu)-OH

CAS: 71989-35-0

Fórmula: C₂₃H₂₇NO₅

Pureza: ≥ 98.0%

Forma y color: White to off-white powder

Peso molecular: 397.46

Ref: 7W-GM9332

Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-tert-butyl-L-threonine

CAS: 71989-35-0

Fórmula: C₂₃H₂₇NO₅

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Light yellow powder to crystal

Peso molecular: 397.47

Ref: 3B-F0505

Fmoc-O-tert-Butyl-L-threonine

CAS: 71989-35-0

Fmoc-O-tert-Butyl-L-threonine

Pureza: 98%

Forma y color: Powder

Peso molecular: 397.46g/mol

Ref: 54-OR350183

Fmoc-Thr(tBu)-OH

CAS: 71989-35-0

Fmoc-Thr(tBu)-OH is an ester hydrochloride that is synthesized by reacting the amino acid, Fmoc-Thr(tBu) with trifluoroacetic acid. It has been used to synthesize a cyclic peptide with a protonated amide group, which allows for stereoselective synthesis of the chloride. This product has shown to be resistant to hydrolysis by atosiban and carbonyl oxygens, and also binds to mammalian cell receptors.

Fórmula: C₂₃H₂₇NO₅

Pureza: Min. 98 Area-%

Forma y color: White Powder

Peso molecular: 397.46 g/mol

Ref: 3D-FF15778

Fmoc-Thr(tBu)-OH

CAS: 71989-35-0

Fmoc-Thr(tBu)-OH is an amino acid that is used for the synthesis of amides and esters. It is prepared by the solid-phase synthesis of 2,6-dichloroacetic acid and Fmoc-protected thiomorpholine. The product can be purified by a combination of saponification and trifluoroacetic acid hydrolysis. This amino acid has acidic properties, which may be due to its ability to form ester or amide bonds with other compounds in the presence of a base.

Fórmula: C₂₃H₂₇NO₅

Pureza: Min. 98.0 Area-%

Peso molecular: 397.48 g/mol

Ref: 3D-FLT-1700-PI