CAS 72088-94-9

Carboxifluoresceína

Descripción:

Carboxifluoresceína es un colorante fluorescente comúnmente utilizado en aplicaciones biológicas y químicas, particularmente en microscopía de fluorescencia y citometría de flujo. Se caracteriza por su fluorescencia verde brillante, que se debe a su estructura conjugada que permite una eficiente absorción y emisión de luz. La sustancia es soluble en agua y exhibe fluorescencia dependiente del pH, lo que la hace útil para estudiar procesos celulares y dinámicas de membrana. Carboxifluoresceína se puede utilizar como trazador en varios ensayos, incluidos aquellos que miden la viabilidad celular, la proliferación y la integridad de la membrana. Su capacidad para formar conjugados estables con proteínas y otras biomoléculas mejora su utilidad en experimentos de etiquetado y seguimiento. Además, a menudo se emplea en la síntesis de sondas fluorescentes y en el desarrollo de biosensores. Las consideraciones de seguridad incluyen manejarlo con cuidado, como con cualquier colorante químico, para evitar posibles irritaciones en la piel o los ojos. En general, Carboxifluoresceína es una herramienta versátil tanto en aplicaciones de investigación como diagnósticas debido a sus distintas propiedades ópticas y compatibilidad con sistemas biológicos.

Fórmula: C₂₁H₁₂O₇

InChI: InChI=1/2C21H12O7/c22-11-2-5-15-17(8-11)27-18-9-12(23)3-6-16(18)21(15)14-4-1-10(19(24)25)7-13(14)20(26)28-21;22-11-2-5-14-17(8-11)27-18-9-12(23)3-6-15(18)21(14)16-7-10(19(24)25)1-4-13(16)20(26)28-21/h2*1-9,22-23H,(H,24,25)

SMILES: c1cc2c(cc1C(=O)O)C(=O)OC12c2ccc(cc2Oc2cc(ccc12)O)O.c1cc2c(cc1C(=O)O)C1(c3ccc(cc3Oc3cc(ccc13)O)O)OC2=O

Sinónimos:

• 3',6'-Dihydroxy-1-Oxo-Spiro[Isobenzofuran-3,9'-Xanthene]-5-Carboxylic Acid
• 3',6'-Dihydroxy-3-Oxo-Spiro[Isobenzofuran-1,9'-Xanthene]-5-Carboxylic Acid
• 3',6'-dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one-acetic acid (1:1)
• 3′,6′-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9′-[9H]xanthene]-ar-carboxylic acid
• 4(5)-Carboxyfluorescein
• 5(6)-Carboxyfluorescein
• 5(6)-Carboxyfluorescein, For Fluorescenc E
• 5(6)-Fam
• 5(6)Carboxy fluorescein
• 5-(And-6)-Carboxyfluorescein
• 9'-[9H]Xanthene]-Ar-Carboxylicacid,3',6'-Dihydroxy-Spiro[Isobenzofuran-1(3H
• C 194
• Carboxyfluorescein
• Fluoresceincarboxylic acid
• Spiro(isobenzofuran-1(3H),9'-(9H)xanthene)-ar-carboxylic acid, 3',6'-dihydroxy-3-oxo-

5(6)-Carboxyfluorescein, mixture of isomers, 97%

CAS: 72088-94-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₂₁H₁₂O₇

Pureza: 97%

Forma y color: Orange to brown or orange-red or orange-brown, Powder or crystalline powder and/or chunks

Peso molecular: 376.32

Ref: 02-L13439

5(6)-Carboxyfluorescein, mixture of isomers

CAS: 72088-94-9

Fórmula: C₄₂H₂₄O₁₄

Pureza: 95%

Forma y color: Solid

Peso molecular: 752.6316

Ref: IN-DA00IKJ4

5(6)-Carboxyfluorescein

CAS: 72088-94-9

5(6)-Carboxyfluorescein

Fórmula: ·C₂₁H₁₂O₇·C₂₁H₁₂O₇

Pureza: 98% (nmr) (Typical Value in Batch COA)

Forma y color: pale red solid

Peso molecular: 752.63g/mol

Ref: 54-BIC1073

5(6)-Carboxyfluorescein

CAS: 72088-94-9

5(6)-Carboxyfluorescein

Pureza: ≥95%

Peso molecular: 376.32g/mol

Ref: 54-BUP18955

5(6)-Carboxyfluorescein

CAS: 72088-94-9

5(6)-Carboxyfluorescein (5-(and-6)-Carboxyfluorescein mixed isomers) contains a carboxylic acid that can be used to react with primary amines via carbodiimide

Fórmula: C₂₁H₁₂O₇

Pureza: 97.57% - 98.85%

Forma y color: Off-White Solid

Peso molecular: 376.32

Ref: TM-T18893

5(6)-Carboxyfluorescein

CAS: 72088-94-9

Fórmula: C₂₁H₁₂O₇

Pureza: ≥ 95%

Forma y color: Yellow to dark orange powder

Peso molecular: 376.32

Ref: 7W-GE4671

5(6)-Carboxyfluorescein

Producto controlado

CAS: 72088-94-9

Applications 5(6)-FAM, A useful reagent for the preparation of hydrolytically stable fluorescent conjugates and is a useful starting material for the synthesis of other fluorescein-derives reagent.
References Theisen, P., et al.: Tetrahedron Lett., 33, 5033 (1992), Mattingly, P.: Bioconjgate Chem., 3, 430 (1992, Bertrand, R., et al.: Biochemistry, 34, 9500 (1995)

Fórmula: C₂₁H₁₂O₇

Forma y color: Dark Brown

Peso molecular: 752.63

Ref: TR-C178315

5(6)-Carboxyfluorescein - mixture

CAS: 72088-94-9

6-Carboxyfluorescein is a fluorescent dye widely used in PCR methodologies, it is used to label the 5' end of oligonucleotides as a reporter in the presence of a quencher at the 3' end (dual labelled probe). During the amplification process, the dye is cleaved, and the fluorescence increases proportionally with the amount of the specific sequence amplified during the PCR process. The development of the fluorescence signal is therefore specifically related to the amplification of the target sequence. It is used to tag DNA and RNA for in vivo and in vitro applications, as well as for structural studies and RNA-protein interactions.

Fórmula: C₂₁H₁₂O₇

Pureza: Min. 95%

Forma y color: Powder

Peso molecular: 376.32 g/mol

Ref: 3D-FC19772

5(6)-Carboxyfluorescein

CAS: 72088-94-9

5(6)-Carboxyfluorescein is a fluorescent dye that can be used as a building block for the synthesis of more complex compounds. It is also used as a reagent for research and detection in various chemical reactions. 5(6)-Carboxyfluorescein has been shown to react with certain amines, alcohols, and thiols to form useful scaffolds for drug discovery. This compound is also used as an intermediate in the production of pharmaceutical drugs and agrochemicals.

Fórmula: C₂₁H₁₂O₇

Peso molecular: 376.33 g/mol

Ref: 3D-C-1825

5(6)-Carboxyfluorescein

CAS: 72088-94-9

M03602 - 5(6)-Carboxyfluorescein

Fórmula: C₄₂H₂₄O₁₄

Pureza: 95%

Forma y color: Solid, Orange solid

Peso molecular: 752.64

Ref: 10-M03602