CAS 72103-53-8

acetato de tuftsin

Descripción:

acetato de tuftsin, con el número CAS 72103-53-8, es un péptido sintético derivado del modulador inmune natural tuftsin, que es un fragmento de la molécula de inmunoglobulina G (IgG). Este compuesto es conocido por sus propiedades inmunoestimulantes, mejorando la actividad de los macrófagos y promoviendo la respuesta inmune. acetato de tuftsin se caracteriza típicamente por su capacidad para modular funciones inmunitarias, lo que lo hace de interés en inmunología y aplicaciones terapéuticas potenciales. A menudo se estudia por su papel en la mejora de la fagocitosis y la producción de citoquinas, lo que puede ser beneficioso en diversas condiciones médicas, incluidas infecciones y cáncer. La forma de acetato indica que es una sal o éster derivado del ácido acético, lo que puede influir en su solubilidad y estabilidad. En general, acetato de tuftsin representa un área significativa de investigación en el desarrollo de terapias inmunitarias y la comprensión de la modulación del sistema inmunológico.

Fórmula: C₂₃H₄₄N₈O₈

InChI: InChI=1/C21H40N8O6.C2H4O2/c1-12(30)16(23)18(32)27-13(6-2-3-9-22)19(33)29-11-5-8-15(29)17(31)28-14(20(34)35)7-4-10-26-21(24)25;1-2(3)4/h12-16,30H,2-11,22-23H2,1H3,(H,27,32)(H,28,31)(H,34,35)(H4,24,25,26);1H3,(H,3,4)

SMILES: CC(C(C(=NC(CCCCN)C(=O)N1CCCC1C(=NC(CCCNC(=N)N)C(=O)O)O)O)N)O.CC(=O)O

Sinónimos:

• L-Arginine, N2-(1-(N2-L-threonyl-L-lysyl)-L-prolyl)-, diacetate (salt)4
• L-threonyl-L-lysyl-L-prolyl-N~5~-(diaminomethylidene)-L-ornithine acetate (1:2)
• threonyllysylprolyl-N~5~-(diaminomethylidene)ornithine acetate (1:1)
• Tuftsin Acetate Salt
• tuftsin acetate
• THR-LYS-PRO-ARG ACETATE SALT
• tuftsin acetate salt hydrate
• H-THR-LYS-PRO-ARG-OH ACETATE SALT
• H-THR-LYS-PRO-ARG-OH ACOH
• Tuftsin diacetate
• TUFTSIN

Tuftsin diacetate

CAS: 72103-53-8

Tuftsin diacetate, Thr-Lys-Pro-Arg, activates macrophages/microglia; it's in immunoglobulin G's Fc and boosts immunity.

Fórmula: C₂₅H₄₈N₈O₁₀

Pureza: 98%

Forma y color: Solid

Peso molecular: 620.7

Ref: TM-TP1846

Tuftsin

Producto controlado

CAS: 72103-53-8

Tuftsin is a cyclic peptide that has been shown to have various biological properties, including anti-inflammatory and immunosuppressive activity. Tuftsin has been shown to inhibit the production of proinflammatory cytokines such as IL-10 by T cells in vitro. Tuftsin also inhibits the activation of toll-like receptors (TLR) and may have a role in inhibiting mycobacterial infection. This drug was found to be well tolerated in humans with congestive heart failure, and is currently being evaluated for its potential use as an adjunct therapy for inflammatory bowel disease. It has also been shown to be effective against opportunistic fungal infections, such as Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus. Tuftsin can be measured using analytical methods such as titration calorimetry or polymerase chain reaction (PCR).

Fórmula: C₂₁H₄₀N₈O₆•2CH₃COOH•4H₂O

Pureza: Min. 95%

Peso molecular: 692.75 g/mol

Ref: 3D-PTF-4020

Tuftsin diacetate

Producto controlado

CAS: 72103-53-8

Tuftsin diacetate is a synthetic peptide derivative, which is a modified form of the natural tetrapeptide tuftsin. This product originates from the enzymatic action on the Fc region of the gamma heavy chain of immunoglobulin G. Tuftsin diacetate functions by enhancing the phagocytic activity of macrophages and neutrophils, leading to an amplified immune response. Its mode of action involves binding to specific cell surface receptors, which stimulates these immune cells and promotes pathogen clearance.

Fórmula: C₂₃H₄₄N₈O₈

Pureza: Min. 95%

Peso molecular: 560.6 g/mol

Ref: 3D-XCA10353